Comparative behaviour of calpain and cathepsin B toward peptidyl acyloxymethyl ketones, sulphonium methyl ketones and other potential inhibitors of cysteine proteinases

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity.

1991 • 595 citations

Structure of papain refined at 1.65 Å resolution

1984 • 508 citations

Evolutionary origin of a calcium-dependent protease by fusion of genes for a thiol protease and a calcium-binding protein?

1984 • 337 citations

Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates.

1984 • 291 citations

Intracellular Calcium-Dependent Proteolysis

2019 • 286 citations

Peptidyl (acyloxy)methyl ketones and the quiescent affinity label concept: the departing group as a variable structural element in the design of inactivators of cysteine proteinases

1991 • 142 citations

The design of peptidyldiazomethane inhibitors to distinguish between the cysteine proteinases calpain II, cathepsin L and cathepsin B

1988 • 139 citations

Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B

1985 • 125 citations

Calpain inhibition by peptide epoxides

1985 • 106 citations

Inhibition of the proteolysis of rat erythrocyte membrane proteins by a synthetic inhibitor of calpain

1988 • 99 citations

Calpains (intracellular calcium-activated cysteine proteinases): Structure-activity relationships and involvement in normal and abnormal cellular metabolism

1990 • 92 citations

Inhibition of Epoxide Derivatives on Chicken Calcium-Activated Neutral Protease (CANP) In Vitro and In Vivo1

1980 • 64 citations

Inactivation of calpain by peptidyl fluoromethyl ketones

1992 • 57 citations

An exploration of the primary specificity site of cathepsin B

1983 • 51 citations

Inhibition of cathepsin B by peptidyl aldehydes and ketones: slow-binding behavior of a trifluoromethyl ketone

1988 • 45 citations

Inactivation of Calpain I and Calpain II by Specificity-Oriented Tripeptidyl Chloromethyl Ketones1

1986 • 41 citations

[62] Inactivation of thiol proteases with peptidyl diazomethyl ketones

1981 • 38 citations

Peptidyl sulfonium salts. A new class of protease inhibitors.

1988 • 35 citations

Investigation of the role of calpain as a stimulus-response mediator in human platelets using new synthetic inhibitors

1991 • 31 citations