The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity.

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

[41] Cathepsin B, cathepsin H, and cathepsin L

1981 • 1,678 citations

L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

1982 • 1,024 citations

The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases.

1988 • 584 citations

Structure of papain refined at 1.65 Å resolution

1984 • 508 citations

The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction.

1990 • 492 citations

Binding of chloromethyl ketone substrate analogs to crystalline papain

1976 • 352 citations

Structure of actinidin, after refinement at 1.7 Å resolution

1980 • 287 citations

Thiol proteases

1985 • 274 citations

Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs.

1986 • 245 citations

A comparison of the heme binding pocket in globins and cytochrome b5.

1975 • 237 citations

Homology of amino acid sequences of rat liver cathepsins B and H with that of papain.

1983 • 231 citations

Cathepsin B and cystatins: evidence for a role in cancer progression.

1990 • 206 citations

Inhibition of cysteine proteinases and dipeptidyl peptidase I by egg-white cystatin

1984 • 163 citations

The specificity of cathepsin B. Hydrolysis of glucagon at the C-terminus by a peptidyldipeptidase mechanism

1978 • 159 citations

Extracellular presence of the lysosomal proteinase cathepsin B in rheumatoid synovium and its activity at neutral pH

1984 • 153 citations

Cysteinyl Proteinases and Their Selective Inactivation

1990 • 136 citations

A protein engineering study of the role of aspartate 158 in the catalytic mechanism of papain

1990 • 123 citations

Biosyntheses and processing of lysosomal cysteine proteinases in rat macrophages

1988 • 121 citations

Inhibitions by E-64 Derivatives of Rat Liver Cathepsin B and Cathepsin L In Vitro and In Vivo 1

1980 • 99 citations

Crystallization and Properties of Cathepsin B from Rat Liver

1979 • 98 citations

Degradation of fructose-1,6-bisphosphate aldolase by cathepsin B

1980 • 95 citations

Amino acid sequence of human liver cathepsin B

1985 • 82 citations

Dissociation of ionizing groups in the binding cleft inversely controls the endo- and exopeptidase activities of cathepsin B.

1987 • 72 citations

Porcine spleen cathepsin B is an exopeptidase.

1986 • 52 citations

An exploration of the primary specificity site of cathepsin B

1983 • 51 citations

Preferential action of rat brain cathepsin B as a peptidyl dipeptidase converting pro-opioid oligopeptides

1986 • 48 citations

Isolation of a cDNA clone for the human lysosomal proteinase cathepsin B.

1986 • 48 citations

A general framework of cysteine-proteinase mechanism deduced from studies on enzymes with structurally different analogous catalytic-site residues Asp-158 and −161 (papain and actinidin), Gly-196 (cathepsin B) and Asn-165 (cathepsin H). Kinetic studies up to pH 8 of the hydrolysis of N-α-benzyloxycarbonyl-<scp>l</scp>-arginyl-<scp>l</scp>-arginine 2-naphthylamide catalysed by cathepsin B and of <scp>l</scp>-arginine 2-naphthylamide catalysed by cathepsin H.

1985 • 47 citations

Intracellular transport and processing of lysosomal cathepsin B

1987 • 44 citations

Preparation of cathepsins B and H by covalent chromatography and characterization of their catalytic sites by reaction with a thiol-specific two-protonic-state reactivity probe. Kinetic study of cathepsins B and H extending into alkaline media and a rapid spectroscopic titration of cathepsin H at pH 3-4

1985 • 43 citations

Crystal and molecular structure of the sulfhydryl protease calotropin DI at 3·2 Å resolution

1982 • 38 citations

Chromophoric and fluorophoric peptide substrates cleaved through the dipeptidyl carboxypeptidase activity of cathepsin B

1987 • 38 citations

Cathepsins B and H from porcine spleen. Purification, polypeptide chain arrangements, and carbohydrate content.

1984 • 34 citations

Amino acid sequence of bovine spleen cathepsin B.

1988 • 30 citations

Gene structure of mouse cathepsin B

1990 • 29 citations

The specificity of cathepsin B.

1981 • 28 citations

N-terminal variants of recombinant stefin B: effect on affinity for papain and cathepsin B.

1990 • 21 citations

Crystallization of recombinant rat cathepsin B.

1990 • 20 citations

A new purification procedure of human kidney cathepsin H, its properties and kinetic data.

1988 • 15 citations

Disulfide Bridges of Boviae Spleen Cathepsin B

1990 • 13 citations