Peptidyl vinyl sulphones: a new class of potent and selective cysteine protease inhibitors: S2P2 specificity of human cathepsin O2 in comparison with cathepsins S and L

[41] Cathepsin B, cathepsin H, and cathepsin L

1981 • 1,678 citations

PRINCIPLES THAT DETERMINE THE STRUCTURE OF PROTEINS

1984 • 645 citations

Vinyl Sulfones as Mechanism-Based Cysteine Protease Inhibitors

1995 • 496 citations

Molecular Cloning of Human cDNA for Cathepsin K: Novel Cysteine Proteinase Predominantly Expressed in Bone

1995 • 357 citations

Determination of the rate constant of enzyme modification by measuring the substrate reaction in the presence of the modifier

1982 • 341 citations

Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease.

1992 • 304 citations

Novel epoxysuccinyl peptides Selective inhibitors of cathepsin B, in vitro

1991 • 271 citations

Human Cathepsin O2, a Novel Cysteine Protease Highly Expressed in Osteoclastomas and Ovary Molecular Cloning, Sequencing and Tissue Distribution

1995 • 241 citations

Functional expression of human cathepsin S in Saccharomyces cerevisiae. Purification and characterization of the recombinant enzyme.

1993 • 159 citations

A comparison of four cathepsins (B, L, N and S) with collagenolytic activity from rabbit spleen

1988 • 158 citations

Protease inhibitors: Role and potential therapeutic use in human cancer

1994 • 134 citations

Prognostic value of the cysteine proteases cathepsins B and cathepsin L in human breast cancer.

1995 • 127 citations

Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B

1985 • 125 citations

Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin b and an inhibitor of matrix metalloproteinases. evidence for two converging pathways of chondrocyte‐mediated proteoglycan degradation

1993 • 123 citations

Structure-activity relationships for inhibition of papain by peptide Michael acceptors

1992 • 105 citations

The Slow, Tight‐Binding Inhibition of Cathepsin B by Leupeptin

1982 • 93 citations

The specificity and elastinolytic activities of bovine cathepsins S and H

1992 • 58 citations

Peptidyl fluoromethyl ketones as inhibitors of cathepsin B

1992 • 52 citations

Epoxysuccinyl dipeptides as selective inhibitors of cathepsin B

1993 • 45 citations

The affinity‐labelling of cathepsin s with peptidyl diazomethyl ketones

1993 • 42 citations

[46] Peptidyl diazomethanes as inhibitors of cysteine and serine proteinases

1994 • 42 citations

Reversible covalent binding of peptide nitriles to papain

1990 • 39 citations

Reversible binding of peptide aldehydes to papain. Structure-activity relationships

1991 • 36 citations

Peptidyl sulfonium salts. A new class of protease inhibitors.

1988 • 35 citations

Potent and selective inactivation of cysteine proteinases with N-peptidyl-O-acyl hydroxylamines

1989 • 35 citations

Hydrolysis of amyloid precursor protein-derived peptides by cysteine proteinases and extracts of rat brain clathrin-coated vesicles

1994 • 24 citations

[47] Peptidyl (Acyloxy)methanes as quiescent affinity labels for cysteine proteinases

1994 • 22 citations

[48] N,O-Diacyl hydroxamates as selective and irreversible inhibitors of cysteine proteinases

1994 • 21 citations

Novel N-peptidyl-O-acyl hydroxamates: selective inhibitors of cysteine proteinases

1993 • 9 citations