Cutting Edge: Ectopic Expression of CD40 Ligand on B Cells Induces Lupus-Like Autoimmune Disease

Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity

1999 • 1,500 citations

Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations

1999 • 1,464 citations

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

1998 • 1,431 citations

The CD40 Antigen and its Ligand

1994 • 1,259 citations

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease

2000 • 1,171 citations

The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation

1994 • 1,099 citations

Repeat-induced gene silencing in mammals

1998 • 884 citations

Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases

2001 • 784 citations

Features of systemic lupus erythematosus in Dnase1-deficient mice

2000 • 781 citations

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

1993 • 756 citations

Spontaneous Autoimmune Disease in FcγRIIB-Deficient Mice Results from Strain-Specific Epistasis

2000 • 747 citations

Cutting Edge: A Role for B Lymphocyte Stimulator in Systemic Lupus Erythematosus

2001 • 723 citations

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

1995 • 710 citations

Systemic Lupus Erythematosus

1996 • 677 citations

Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice

2000 • 579 citations

Measurement of increases in anti‐double‐stranded dna antibody levels as a predictor of disease exacerbation in systemic lupus erythematosus

1990 • 558 citations

Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production.

1996 • 516 citations

Functions of CD40 on B cells, dendritic cells and other cells

1997 • 490 citations

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

1995 • 475 citations

Characterization of the B Lymphocyte Populations in Lyn-Deficient Mice and the Role of Lyn in Signal Initiation and Down-Regulation

1997 • 451 citations

Attenuation of Apoptosis Underlies B Lymphocyte Stimulator Enhancement of Humoral Immune Response

2000 • 431 citations

Systemic Lupus Erythematosus

1994 • 407 citations

Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes.

1996 • 360 citations

Anti-CD40 ligand antibody treatment prevents the development of lupus-like nephritis in a subset of New Zealand black x New Zealand white mice. Response correlates with the absence of an anti-antibody response.

1996 • 220 citations

CD40 molecules induce down-modulation and endocytosis of T cell surface T cell-B cell activating molecule/CD40-L. Potential role in regulating helper effector function.

1994 • 205 citations

Laboratory tests as predictors of disease exacerbations in systemic lupus erythematosus. Why some tests fail

1996 • 180 citations

Genetic dissection of systemic lupus erythematosus

1999 • 158 citations

Systemic Lupus Erythematosus

1991 • 113 citations

The genetic contribution of the NZB mouse to the renal disease of the NZB x NZW hybrid.

1977 • 91 citations

Thymus dysfunction and chronic inflammatory disease in gp39 transgenic mice

1997 • 86 citations

CD40 ligand expressed on B cells in the BXSB mouse model of systemic lupus erythematosus.

1997 • 60 citations

Lupus nephritis: update on pathogenesis and disease mechanisms.

1999 • 57 citations