Shortening the Infectious Period Does Not Alter Expansion of CD8 T Cells but Diminishes Their Capacity to Differentiate into Memory Cells

Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection

1998 • 1,996 citations

Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

1998 • 1,890 citations

Lineage relationship and protective immunity of memory CD8 T cell subsets

2003 • 1,833 citations

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells

2003 • 1,790 citations

Effector and memory T-cell differentiation: implications for vaccine development

2002 • 1,757 citations

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

2003 • 1,623 citations

Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment

2003 • 1,500 citations

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

2003 • 1,466 citations

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

2001 • 1,277 citations

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

2003 • 1,220 citations

TNF/iNOS-Producing Dendritic Cells Mediate Innate Immune Defense against Bacterial Infection

2003 • 1,129 citations

Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off

1998 • 989 citations

Molecular and Functional Profiling of Memory CD8 T Cell Differentiation

2002 • 962 citations

The Duration of Antigenic Stimulation Determines the Fate of Naive and Effector T Cells

1998 • 890 citations

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

2001 • 861 citations

Massive Expansion of Antigen-Specific CD8+ T Cells during an Acute Virus Infection

1998 • 794 citations

Distinct Dendritic Cell Populations Sequentially Present Antigen to CD4 T Cells and Stimulate Different Aspects of Cell-Mediated Immunity

2003 • 702 citations

Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

2001 • 600 citations

Programmed contraction of CD8+ T cells after infection

2002 • 586 citations

Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells

2002 • 584 citations

Coordinate Regulation of Complex T Cell Populations Responding to Bacterial Infection

1998 • 535 citations

T Cell Memory

2002 • 529 citations

Progressive differentiation and selection of the fittest in the immune response

2002 • 503 citations

Early Programming of T Cell Populations Responding to Bacterial Infection

2000 • 492 citations

T cell fitness determined by signal strength

2003 • 478 citations

Antigen presentation to naive CD4 T cells in the lymph node

2003 • 467 citations

Dynamic programming of CD8+ T lymphocyte responses

2003 • 401 citations

What messenger RNA capping tells us about eukaryotic evolution

2002 • 351 citations

Cutting Edge: Antigen-Independent CD8 T Cell Proliferation

2001 • 277 citations

4-1BB Ligand, a Member of the TNF Family, Is Important for the Generation of Antiviral CD8 T Cell Responses

1999 • 259 citations

IL-2 Is Not Required for the Initiation of CD8 T Cell Cycling but Sustains Expansion

2003 • 232 citations

Recombinant Vaccinia Virus-Induced T-Cell Immunity: Quantitation of the Response to the Virus Vector and the Foreign Epitope

2002 • 204 citations

Role of CD28-B7 Interactions in Generation and Maintenance of CD8 T Cell Memory

2001 • 192 citations

A Novel Approach of Direct Ex Vivo Epitope Mapping Identifies Dominant and Subdominant CD4 and CD8 T Cell Epitopes from Listeria monocytogenes

2001 • 164 citations

Two Distinct Stages in the Transition from Naive CD4 T Cells to Effectors, Early Antigen-Dependent and Late Cytokine-Driven Expansion and Differentiation

2000 • 161 citations

CD4 T Cell-Dependent CD8 T Cell Maturation

2004 • 137 citations

Long-Term CD4 Th1 and Th2 Memory following Acute Lymphocytic Choriomeningitis Virus Infection

1998 • 126 citations

Repeated Antigen Exposure Is Necessary for the Differentiation, But Not the Initial Proliferation, of Naive CD4+ T Cells

2002 • 102 citations

Functional Flexibility in T Cells

2000 • 93 citations

Continued Antigen Stimulation Is Not Required During CD4+ T Cell Clonal Expansion

2002 • 84 citations

Inducible Costimulator Protein Controls the Protective T Cell Response Against Listeria monocytogenes

2002 • 40 citations

Homing to Nonlymphoid Tissues Is Not Necessary for Effector Th1 Cell Differentiation

2003 • 8 citations