Circadian rhythm of cell division

Inhibitors of mammalian G1 cyclin-dependent kinases.

1995 • 3,258 citations

G1 phase progression: Cycling on cue

1994 • 2,706 citations

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1994 • 2,154 citations

Cancer: Principles and Practice of Oncology

1994 • 1,825 citations

The principles and practice of medicine

1938 • 1,719 citations

Methods for cosinor-rhythmometry.

1979 • 1,693 citations

Cell population kinetics in the intestinal epithelium of the mouse

1959 • 1,446 citations

Translational Control of p27 ^Kip1 Accumulation During the Cell Cycle

1996 • 864 citations

Photoperiodism and related phenomena in plants and animals

1959 • 762 citations

Dominoes and Clocks: the Union of Two Views of the Cell Cycle

1989 • 750 citations

Mitosis in transition

1994 • 745 citations

Cancer. A Comprehensive Treatise

1975 • 742 citations

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation

1994 • 742 citations

cdc2 protein kinase is complexed with both cyclin A and B: Evidence for proteolytic inactivation of MPF

1989 • 666 citations

The constant renewal of the intestinal epithelium in the albino rat

1948 • 534 citations

The cyclic AMP-mediated stimulation of cell proliferation

1989 • 464 citations

Cdc2 regulatory factors

1994 • 414 citations

Effects of melatonin on vertebrate circadian systems

1990 • 414 citations

Driving the cell cycle: M phase kinase, its partners, and substrates

1990 • 404 citations

Chronomodulated Versus Fixed-Infusion—Rate Delivery of Ambulatory Chemotherapy With Oxaliplatin, Fluorouracil, and Folinic Acid (Leucovorin) in Patients With Colorectal Cancer Metastases: a Randomized Multi-institutional Trial

1994 • 386 citations

Circadian Timing of Cancer Chemotherapy

1985 • 358 citations

A chronopharmacologic phase II clinical trial with 5-fluorouracil, folinic acid, and oxaliplatin using an ambulatory multichannel programmable pump. High antitumor effectiveness against metastatic colorectal cancer

1992 • 336 citations

Chronobiology in hematology and immunology

1983 • 303 citations

Biologic Rhythms in Clinical and Laboratory Medicine

1992 • 274 citations

The Langerhans Cell

1983 • 265 citations

A prospective epidemiological study

1964 • 231 citations

Genetic analysis of the role of cAMP in yeast

1985 • 200 citations

Simple and Complex Cell Cycles

1989 • 192 citations

Diurnal Fluctuations in the Numbers of DNA Synthesizing Nuclei in Various Mouse Tissues

1963 • 178 citations

Warner-Lambert/Parke-Davis Award lecture. Cellular and molecular mechanisms that direct leukocyte traffic.

1990 • 170 citations

Circadian rhythm-varying plasma concentration of 5-fluorouracil during a five-day continuous venous infusion at a constant rate in cancer patients.

1988 • 163 citations

Increased Tolerance of Leukemic Mice to Arabinosyl Cytosine with Schedule Adjusted to Circadian System

1972 • 162 citations

Circadian rhythm of erythropoietin in human serum

1989 • 159 citations

Circadian variation in cell division of the mouse alimentary tract, bone marrow and corneal epithelium

1978 • 155 citations

Circadian rhythm of cellular proliferation in the human rectal mucosa

1991 • 154 citations

DNA synthesis in human bone marrow is circadian stage dependent

1991 • 152 citations

Mitotic activity in the adult male mouse, Mus musculus L. The diurnal cycles and their relation to waking and sleeping

1948 • 152 citations

Circadian cancer therapy.

1993 • 151 citations

Cell cycle phase specificity of antitumor agents.

1972 • 150 citations

MITOTIC RATES AND RENEWAL TIMES OF THE DIGESTIVE TRACT EPITHELIA IN THE RAT

1960 • 146 citations

24-Hour Rhythms at Several Levels of Integration in Mice on Different Lighting Regimens.

1958 • 140 citations

Chronopharmacology; Cellular and biochemical interactions

1990 • 134 citations

Diurnal Variation of Proliferative Activity in the Human Bone Marrow

1965 • 131 citations

Chronopharmacology: Cellular and biochemical interactions

1990 • 126 citations

Diurnal fluctuations in the number of cells in mitosis and DNA synthesis in the jejunum of the mouse

1969 • 125 citations

Mitotic Indices of Human Bone Marrow Cells. I. Number and Cytologic Distribution of Mitoses

1962 • 115 citations

Biological rhythms in clinical practice

1989 • 111 citations

CIRCADIAN RHYTHMS IN MOUSE EPIDERMAL BASAL CELL PROLIFERATION

1979 • 110 citations

Mitotic activity in the human epidermis

1959 • 109 citations

Circadian characteristics of circulating interleukin-6 in men

1995 • 106 citations

MAINTENANCE CHEMOTHERAPY FOR CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA: BETTER IN THE EVENING

1985 • 105 citations

Circadian rhythm in toxicities and tissue uptake of 1,2-diamminocyclohexane(trans-1)oxalatoplatinum(II) in mice.

1989 • 104 citations

Circadian patterning of continuous floxuridine infusion reduces toxicity and allows higher dose intensity in patients with widespread cancer.

1989 • 100 citations

Neoplasms--comparative pathology of growth in animals, plants, and man

1981 • 99 citations

Circadian Rhythmometry of Serum Interleukin-2, Interleukin-10, Tumor Necrosis Factor-α, and Granulocyte-Macrophage Colony-Stimulating Factor in Men

1995 • 99 citations

Circadian gating of S phase in human ovarian cancer.

1987 • 99 citations

Circadian rhythms in hairless mouse epidermal DNA-synthesis as measured by double labelling with H3-thymidine (H3Tdr.)

1972 • 92 citations

Chronobiology of the intestinal tract of the mouse

1983 • 86 citations

Calcium, cyclic AMP and protein kinase C ? partners in mitogenesis

1987 • 86 citations

Mitotic Rhythm in Human Epidermis

1938 • 80 citations

A Review and Mathematical Analysis of Circadian Rhythms in Cell Proliferation in Mouse, Rat, and Human Epidermis

1991 • 76 citations

Circadian and/or circahemidian rhythms in nine lymphocyte-related variables from peripheral blood of healthy subjects.

1985 • 74 citations

Diurnal Variation in Mouse and Rat Liver Sulfhydryl.

1958 • 73 citations

THE DIURNAL MITOTIC RHYTHM IN THE HUMAN EPIDERMIS

1968 • 73 citations

DNA synthesis and ploidy in non-Hodgkin's lymphomas demonstrate intrapatient variation depending on circadian stage of cell sampling.

1993 • 68 citations

Colony-forming unit-granulocyte-macrophage and DNA synthesis of human bone marrow are circadian stage-dependent and show covariation

1992 • 67 citations

Circadian variations of epithelial cell proliferation in human rectal crypts

1994 • 66 citations

Circadian Time-Dependent Response of Childhood Lymphoblastic Leukemia to Chemotherapy: A Long-Term Follow-up Study of Survival

1993 • 60 citations

Control of a Murine Plasmacytoma With Doxorubicin-Cisplatin: Dependence on Circadian Stage of Treatment

1989 • 59 citations

Circadian rhythms in mitotic activity and ³H‐thymidine uptake in the duodenum: Effect of isoproterenol on the mitotic rhythm

1972 • 57 citations

Survival and cure of leukemic mice after circadian optimization of treatment with cyclophosphamide and 1-beta-D-arabinofuranosylcytosine.

1977 • 56 citations

Inhibitory effects of a synthetic pentapeptide on hemopoietic stem cells in vitro and in vivo.

1984 • 56 citations

Circadian variations in mouse bone marrow.

1983 • 51 citations

Circadian Periodicity of Bone Marrow Mitotic Activity and Reticulocyte Counts in Rats and Mice

1969 • 51 citations

Circadian and seasonal rhythms in murine bone marrow colony-forming cells affect tolerance for the anticancer agent 4'-O-tetrahydropyranyladriamycin (THP).

1988 • 51 citations

Effect of the pineal gland on circadian rhythmicity of colony forming units for granulocytes and macrophages (CFU‐GM) from rat bone marrow cell cultures

1992 • 51 citations

Circadian variation of 5-fluorouracil catabolism in isolated perfused rat liver.

1989 • 50 citations

Differences between pulsatile or continuous exposure to melatonin on MCF-7 human breast cancer cell proliferation

1994 • 50 citations

Determination of the Therapeutic Index of Floxuridine by Its Circadian Infusion Pattern

1990 • 49 citations

Stable circadian mechanisms of toxicity of two platinum analogs (cisplatin and carboplatin) despite repeated dosages in mice.

1990 • 48 citations

Change in the rate of CO2 production in synchronous cultures of the fission yeast Schizosaccharomyces pombe: A periodic cell cycle event that persists after the DNA-division cycle has been blocked

1986 • 48 citations

Manipulation of the Mitotic Cycle in the Treatment of Acute Myelogenous Leukaemia

1976 • 47 citations

Circadian bioperiodic response of mice bearing advanced L1210 leukemia to combination therapy with adriamycin and cyclophosphamide.

1980 • 43 citations

Simultaneous measurement of DNA content and cell‐surface immunofluorescence of human bone marrow cells using a single laser flow cytometer

1990 • 43 citations

Further studies on the circadian rhythm in the proliferative activity of mouse intestinal epithelium

1970 • 42 citations

CIRCADIAN INFLUENCE ON THE WAVE FORM OF THE FREQUENCY OF LABELED MITOSES IN MOUSE CORNEAL EPITHELIUM

1975 • 42 citations

Circadian influence on the frequency of labeled mitoses method in the stratified squamous epithelium of the mouse esophagus and tongue

1976 • 41 citations

Close reproduction by different laboratories of characteristics of circadian rhythm in 1-beta-D-arabinofuranosylcytosine tolerance by mice.

1976 • 41 citations

Glutathione Content in Human Bone Marrow and Circadian Stage Relation to DNA Synthesis

1991 • 41 citations

DNA cell cycle distribution and glutathione (GSH) content according to circadian stage in bone marrow of cancer patients

1992 • 40 citations

The Neutrophilic Granulocyte

1989 • 40 citations

Persistence of Mitotic Circadian Rhythm of a Transplantable Mammary Carcinoma After 35 Generations: Its Bearing on the Success of Treatment With Endoxan<xref ref-type="fn" rid="FN2">2</xref>

1965 • 37 citations

Diurnal variation in labelling index in human buccal epithelium

1993 • 36 citations

Prevention of hematotoxic side effects of cytostatic drugs in mice by a synthetic hemoregulatory peptide.

1990 • 33 citations

Cell cycle effects of drugs

1986 • 32 citations

Circadian changes in cyclic amp levels in synchronously dividing and stationary-phase cultures of the achlorophyllous ZC mutant of Euglena gracilis

1989 • 32 citations

Circannual variations of circadian periodicity in murine colony-forming cells.

1984 • 29 citations

Effect of hypophysectomy on mitotic proliferation in gastric epithelium

1963 • 29 citations

Influence of the Circadian Rhythm in Cell Division on Radiation-Induced Mitotic Delay in Vivo

1982 • 28 citations

Zum Nachweis eines 24-Stundenrhythmus der Mitosen bei Ratte und Maus

1947 • 28 citations

Flow cytometric evaluation of ovarian cancer

1993 • 28 citations

In vitro chronopharmacology of recombinant mouse IL-3, mouse GM-CSF, and human G-CSF on murine myeloid progenitor cells.

1995 • 27 citations

Effects of aclacinomycin on cell survival and cell cycle progression of cultured mammalian cells.

1981 • 27 citations

The myelotoxicity of carboplatin is influenced by the time of its administration

1990 • 27 citations

Kinetics of epidermal cell proliferation in experimental skin carcinogenesis.

1963 • 26 citations

Circadian rhythmicity in DNA synthesis in untreated and saline-treated mice as a basis for improved chronochemotherapy.

1981 • 26 citations

Steroid modulation of naturally occurring diurnal variation in circulating pluripotential haematopoietic cells (CFU‐GEMM)

1983 • 25 citations

Nucleoside diphosphokinase, an enzyme with step changes in activity during the cell cycle of the fission yeast Schizosaccharomyces pombe: I persistence of steps after a block to the DNA-division cycle

1986 • 25 citations

Age‐related differences and circadian and seasonal variations of myelopoietic progenitor cell (CFU‐GM) numbers in mice

1988 • 25 citations

In vivo determinations of labelling index of metastatic colorectal carcinoma and normal colonic mucosa using intravenous infusions of bromodeoxyuridine

1988 • 24 citations

Chronobiology of Cell Proliferation

1983 • 24 citations

CALCIUM AND THE CONTROL OF CIRCADIAN MITOTIC ACTIVITY IN RAT BONE MARROW AND THYMUS

1974 • 23 citations

Surface detection of circadian rhythm in32P content of cancer of the breast

1968 • 22 citations

The Circadian Optimal Time for Hepatectomy in the Study of Liver Regeneration

1985 • 21 citations

Changes in mitotic activity in rats in relation to the time of day or night

1958 • 20 citations

Hematopoiesis occurs in rhythms.

1995 • 20 citations

Effect of Fasting on Circadian Rhythmicity in Deoxyribonucleic Acid Synthesis of Several Murine Tissues

1984 • 19 citations

The Role of Ions and Second Messengers in Circadian Clock Function

1992 • 19 citations

Effects of the L isomer (+)-1,2-bis(3,5-dioxopiperazine-1-yl)propane on cell survival and cell cycle progression of cultured mammalian cells.

1981 • 18 citations

Circadian and Ultradian Cytokinetic Rhythms of Spontaneous Human Cancera

1991 • 18 citations

Circadian variation in colony-forming ability of presumably intact murine bone marrow cells.

1975 • 18 citations

Several cytokinetic methods for showing circadian variation in normal murine tissue and in a tumor

1983 • 18 citations

MITOSENPERIODIK IN DER NEBENNIERENRINDE, SCHILDDRüSE, IM DUODENAL- UND MUNDHöHLENEPITHEL DER RATTE

1956 • 17 citations

A Possible Link between Diurnal Variations in Radiation Sensitivity and Cell Division in Bone Marrow of Male Mice

1970 • 16 citations

Rhythmic variations of different hemopoietic cell lines and maturation stages in aging mice

1988 • 15 citations

Flow cytometric assay for the measurement of human bone marrow phenotype, function and cell cycle

1990 • 15 citations

Resetting the circadian cycle

1995 • 14 citations

Circulating CALLA-positive lymphocytes exhibit circadian rhythms in man

1985 • 14 citations

Comparison between diurnal changes and changes induced by hydrocortisone and epinephrine in circulating myeloid progenitor cells (CFU-GM) in man.

1984 • 14 citations

Circadian variation in cell proliferation and maturation

1991 • 14 citations

Circadian Variations in Mouse Hematopoiesis II. Sex Differences in Mitotic Indices of Femoral Diaphyseal Marrow Cells

1971 • 13 citations

Effect of Thioacetamide on the Incorporation of [³H]-Thymidine into Dna of 13 Tissues and on the Mitotic Index of the Corneal Epithelium of Bd2F₁in Male Mice while Taking into Consideration Circadian Variation

1986 • 12 citations

On circadian rhythms in human epidermal cell proliferation.

1991 • 11 citations

Heterogeneity in the mouse epidermal cell cycle analysed by computer simulations

1993 • 11 citations

Biological properties of partially purified granulocyte extract (chalone) assayed in soft agar culture

1981 • 11 citations

A relationship between adenosine 3′–5′-cyclic monophosphate levels and deoxyribonucleic acid synthesis in

1982 • 11 citations

Bone marrow disorders : the biological basis of clinical problems

1985 • 10 citations

Comparison of the circadian variation in cell proliferation in normal and neoplastic colonic epithelial cells

1985 • 10 citations

The protein-polysaccharide complex of the developing human periodontium

1967 • 10 citations

Physiological regeneration in the mucosa of the small intestine of hypophysectomized rats

1961 • 9 citations

KINETIC PERTURBATIONS DURING CANCER THERAPY*

1982 • 8 citations

Normal and Abnormal Cell Proliferation in Mice Especially as It Relates to Cancer

1992 • 8 citations

The influence of rate of cell entry to S phase on the labelling index of human buccal epithelium

1995 • 7 citations

Circadian Stage Dependent Variation of Cortisol Related to DNA Synthesis in Human Bone Marrow

1991 • 7 citations

Biological and chemical properties of the hemoregulatory peptide and possibilities for clinical applications

1989 • 6 citations

Granulopoietic Toxicity of Cytotoxic Agents: Pathogenesis, Pathophysiology, Methods of Modulation, and Clinical Aspects

1982 • 6 citations

Changes in³²P counting-rate in human and animal tumours

1968 • 6 citations

11th International Congress of Anatomy. Part C. Biological Rhythms in Structure and Function

1982 • 5 citations

EFFECTS OF INTESTINALLY ABSORBED THYMIDINE ON TRITIATED THYMIDINE UTILIZATION

1979 • 4 citations

[On the level and 24-hour rhythm of mitotic activity in hypophysectomized rats].

1962 • 4 citations

Ara-C cytokinetic studies in normal tissues in vivo

1982 • 3 citations

Implications of Certain Cell Kinetic and Biological Parameters for Preoperative Chemotherapy

1986 • 2 citations