Inhibition of the cAMP Pathway Decreases Early Long-Term Potentiation at CA1 Hippocampal Synapses

Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

1990 • 1,507 citations

Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory

1997 • 1,228 citations

Effects of cAMP Simulate a Late Stage of LTP in Hippocampal CA1 Neurons

1993 • 1,212 citations

Different Training Procedures Recruit Either One or Two Critical Periods for Contextual Memory Consolidation, Each of Which Requires Protein Synthesis and PKA

1998 • 523 citations

The CaM kinase II hypothesis for the storage of synaptic memory

1994 • 510 citations

Regulation of NMDA Receptors by an Associated Phosphatase-Kinase Signaling Complex

1999 • 497 citations

Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization.

1994 • 488 citations

Calcium-Stimulated Adenylyl Cyclase Activity Is Critical for Hippocampus-Dependent Long-Term Memory and Late Phase LTP

1999 • 482 citations

Gating of CaMKII by cAMP-Regulated Protein Phosphatase Activity During LTP

1998 • 452 citations

Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory

1998 • 431 citations

Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice.

1995 • 375 citations

D1/D5 Dopamine Receptor Activation Increases the Magnitude of Early Long-Term Potentiation at CA1 Hippocampal Synapses

1996 • 374 citations

Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons

1994 • 371 citations

Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin

1998 • 355 citations

Can molecules explain long-term potentiation?

1999 • 333 citations

Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79.

1992 • 327 citations

Postsynaptic CAMP pathway gates early LTP in hippocampal CA1 region

1995 • 326 citations

Cyclic adenosine 3',5'‐monophosphate mediates beta‐receptor actions of noradrenaline in rat hippocampal pyramidal cells.

1986 • 308 citations

Activity-Dependent β-Adrenergic Modulation of Low Frequency Stimulation Induced LTP in the Hippocampal CA1 Region

1996 • 282 citations

Pka mediates the effects of monoamine transmitters on the K+ current underlying the slow spike frequency adaptation in hippocampal neurons

1993 • 281 citations

Apical Dendritic Location of Slow Afterhyperpolarization Current in Hippocampal Pyramidal Neurons: Implications for the Integration of Long-Term Potentiation

1996 • 260 citations

Recruitment of New Sites of Synaptic Transmission During the cAMP-Dependent Late Phase of LTP at CA3–CA1 Synapses in the Hippocampus

1997 • 225 citations

Postsynaptic Inhibitors of Calcium/Calmodulin-Dependent Protein Kinase Type II Block Induction But Not Maintenance of Pairing-Induced Long-Term Potentiation

1997 • 217 citations

NMDA Receptor Activation Increases Cyclic AMP in Area CA1 of the Hippocampus via Calcium/Calmodulin Stimulation of Adenylyl Cyclase

1993 • 214 citations

Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase.

1995 • 212 citations

Impaired hippocampal plasticity in mice lacking the Cbeta1 catalytic subunit of cAMP-dependent protein kinase.

1996 • 169 citations

D1/D5 Dopamine Receptors Inhibit Depotentiation at CA1 Synapses via cAMP-Dependent Mechanism

1998 • 167 citations

Transient Activation of Cyclic AMP-dependent Protein Kinase during Hippocampal Long-term Potentiation

1996 • 163 citations

Cyclic AMP induces functional presynaptic boutons in hippocampal CA3–CA1 neuronal cultures

1999 • 157 citations

Protein kinase and phosphatase activity regulate the form of synaptic plasticity expressed

1996 • 56 citations

Evidence that Ca/calmodulin-dependent protein kinase mediates the modulation of the Ca 2+ -dependent K + current, I AHP , by acetylcholine, but not by glutamate, in hippocampal neurons

1996 • 48 citations

Evidence that Ca/calmodulin-dependent protein kinase mediates the modulation of the Ca2+-dependent K+ current,I AHP, by acetylcholine, but not by glutamate, in hippocampal neurons

1996 • 26 citations

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