ATP-Activated Channels in Excitable Cells

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

ATP-regulated K+ channels in cardiac muscle

1983 • 2,350 citations

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures

1980 • 2,218 citations

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart1

1929 • 1,470 citations

Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment

1985 • 1,213 citations

The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart

1987 • 1,186 citations

GTP-binding proteins couple cardiac muscarinic receptors to a K channel

1985 • 868 citations

Cell membrane receptors for drugs and hormones: A multidisciplinary approach

1979 • 850 citations

A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle

1987 • 786 citations

Inward current channels activated by intracellular Ca in cultured cardiac cells

1981 • 687 citations

Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue

1985 • 527 citations

Physiological roles for adenosine and adenosine 5′-triphosphate in the nervous system

1981 • 484 citations

Single Ca2+-activated nonselective cation channels in neuroblastoma

1982 • 446 citations

Suramin: a reversible P₂‐purinoceptor antagonist in the mouse vas deferens

1988 • 426 citations

Pharmacological evidence that adenosine triphosphate and noradrenaline are co‐transmitters in the guinea‐pig vas deferens.

1984 • 416 citations

ATP excites a subpopulation of rat dorsal horn neurones

1983 • 389 citations

Separation of sodium and calcium currents in the somatic membrane of mollusc neurones. With an Appendix by Yu A. Shakhovalov

1977 • 367 citations

The permeability of the endplate channel to organic cations in frog muscle.

1980 • 362 citations

The use of the slowly degradable analog, α,β-methylene ATP, to produce desensitisation of the P2-purinoceptor: Effect on non-adrenergic, non-cholinergic responses of the guinea-pig urinary bladder

1982 • 337 citations

Cyclic GMP-sensitive conductance of retinal rods consists of aqueous pores

1986 • 336 citations

Receptor for ATP in the membrane of mammalian sensory neurones

1983 • 335 citations

Single cyclic GMP-activated channel activity in excised patches of rod outer segment membrane

1986 • 335 citations

ATP as a co-transmitter in rat tail artery

1984 • 315 citations

Inhibition of excitatory junction potentials in guinea-pig vas deferens by α, β-methylene-ATP: Further evidence for ATP and noradrenaline as cotransmitters

1984 • 301 citations

Cell membrane receptors for drugs and hormones : a multidisciplinary approach

1978 • 282 citations

Isolated atrial myocytes: adenosine and acetylcholine increase potassium conductance

1983 • 277 citations

Characterization of responses of isolated rat hepatocytes to ATP and ADP.

1985 • 269 citations

ATP-activated channels in rat and bullfrog sensory neurons: concentration dependence and kinetics

1990 • 243 citations

Physiological and regulatory functions of adenosine and adenine nucleotides

1980 • 228 citations

Cotransmitters in the Motor Nerves of the Guinea Pig Vas Deferens: Electrophysiological Evidence

1982 • 219 citations

'Concentration‐clamp' study of gamma‐aminobutyric‐acid‐induced chloride current kinetics in frog sensory neurones.

1986 • 218 citations

Activation of ion channels in the frog end‐plate by high concentrations of acetylcholine.

1988 • 214 citations

Stability Constants of Metal Complexes with Mononucleotides.

1958 • 214 citations

P2-purinergic receptors are coupled to two signal transduction systems leading to inhibition of cAMP generation and to production of inositol trisphosphate in rat hepatocytes.

1987 • 213 citations

Release of adenosine triphosphate from isolated adult heart cells in response to hypoxia

1977 • 201 citations

Adenosine 5′-0(3-thiotriphosphate) in the control of phosphorytase activity

1974 • 190 citations

Noradrenaline and adenosine triphosphate as co‐transmitters of neurogenic vasoconstriction in rabbit mesenteric artery.

1985 • 187 citations

Cationic channels activated by extracellular atp in rat sensory neurons

1988 • 174 citations

Ecto-protein kinase activity on the external surface of neural cells

1986 • 173 citations

Dependence of acetylcholine desensitization on the membrane potential of frog muscle fibre and on the ionic changes in the medium

1970 • 172 citations

Is ATP a central synaptic mediator for certain primary afferent fibers from mammalian skin?

1984 • 165 citations

Intracellular Ca2+ mobilization activated by extracellular ATP in Ehrlich ascites tumor cells.

1985 • 159 citations

An ATP‐sensitive conductance in single smooth muscle cells from the rat vas deferens.

1988 • 152 citations

Activation and inhibition of calcium‐dependent histamine secretion by ATP ions applied to rat mast cells.

1979 • 151 citations

Evidence for adenosine triphosphate as an excitatory transmitter in guinea‐pig, rabbit and pig urinary bladder.

1988 • 149 citations

Extracellular ATP perturbs transmembrane ion fluxes, elevates cytosolic [Ca2+], and inhibits phagocytosis in mouse macrophages.

1985 • 148 citations

ATP-activated channels in rat and bullfrog sensory neurons: current- voltage relation and single-channel behavior

1990 • 145 citations

Physiological and regulatory functions of adenosine and adenine nucleotides

1979 • 144 citations

Transmitter-like action of ATP on patched membranes of cultured myoblasts and myotubes

1983 • 142 citations

Adenosine triphosphate stimulates inositol phospholipid metabolism and prostacyclin formation in adrenal medullary endothelial cells by means of P2-purinergic receptors.

1987 • 141 citations

Action of externally applied adenosine triphosphate on single smooth muscle cells dispersed from rabbit ear artery.

1987 • 130 citations

Purinergic Neurotransmission and Neuromodulation

1983 • 124 citations

M Currents

1988 • 121 citations

Two ATP-activated conductances in bullfrog atrial cells.

1988 • 120 citations

ATP and other adenine compounds increase mechanical activity and inositol trisphosphate production in rat heart.

1988 • 114 citations

INCREASE OF ACETYLCHOLINE‐RECEPTOR SENSITIVITY BY ADENOSINE TRIPHOSPHATE: A NOVEL ACTION OF ATP ON ACh‐SENSITIVITY

1981 • 106 citations

ATP4− and ATP·Mg inhibit the ATP-sensitive K+ channel of rat ventricular myocytes

1988 • 99 citations

Permeabilization of transformed cells in culture by external ATP

1985 • 92 citations

Excitatory action of ATP on embryonic chick muscle

1986 • 91 citations

Receptors for ATP in rat sensory neurones: the structure‐function relationship for ligands

1988 • 89 citations

Electrical responses of smooth muscle cells of the rabbit ear artery to adenosine triphosphate.

1985 • 82 citations

Properties of glycine-activated conductances in rat brain neurones

1988 • 81 citations

Excitation of single sensory neurones in the rat caudal trigeminal nucleus by iontophoretically applied adenosine 5′-triphosphate

1983 • 80 citations

Actions of ATP and α,β‐methylene ATP on neuromuscular transmission and smooth muscle membrane of the rabbit and guinea‐pig mesenteric arteries

1985 • 76 citations

Nucleotides such as ATP may control the activity of ion channels

1987 • 75 citations

Adenosine triphosphate-activated inward current in isolated smooth muscle cells from rat vas deferens

1987 • 75 citations

Potentiation of postjunctional cholinergic sensitivity of rat diaphragm muscle by high-energy-phosphate adenine nucleotides

1976 • 75 citations

ATP Produces Vasodilation via P<sub>1</sub> Purinoceptors and Vasoconstriction via P<sub>2</sub> Purinoceptors in the Isolated Rabbit Central Ear Artery

1985 • 71 citations

Modulatory actions of ATP on membrane potentials of bullfrog sympathetic ganglion cells

1983 • 70 citations

Adenosine 5'‐triphosphate activates acetylcholine receptor channels in cultured Xenopus myotomal muscle cells.

1988 • 69 citations

ATP stimulates inositol phosphates accumulation and calcium mobilization in a primary culture of rat aortic myocytes

1987 • 68 citations

Activation of single ion channels from toad retinal rod inner segments by cyclic GMP: concentration dependence.

1988 • 64 citations

The effect of adenyl compounds on the rat heart

1983 • 62 citations

Inotropic responses of the frog ventricle to adenosine triphosphate and related changes in endogenous cyclic nucleotides.

1980 • 57 citations

Nanomolar concentrations of extracellular ATP activate membrane Ca channels in snail neurones

1982 • 53 citations

Effect of adenosine triphosphate on the sensitivity of the nicotinic acetylcholine‐receptor in the bullfrog sympathetic ganglion cell

1985 • 44 citations

Externally applied adenosine-5′-triphosphate causes inositol triphosphate accumulation in cultured chick myotubes

1987 • 41 citations

Evidence that ATP is a neurotransmitter in the frog heart

1986 • 41 citations

Nature of Catecholamine-like Actions of ATP and Other Energy Rich Nucleotides on the Bullfrog Atrial Muscle

1978 • 40 citations

ATP-evoked membrane responses inXenopus oocytes

1986 • 37 citations

Comparative study of the actions of AP₅ A and α,β‐methylene ATP on nonadrenergic, noncholinergic neurogenic excitation in the guinea‐pig vas deferens

1988 • 37 citations

The ionic selectivity of the light‐sensitive current in isolated rods of the tiger salamander.

1988 • 36 citations

Alpha-subunit of Gk activates atrial K+ channels of chick, rat, and guinea pig

1988 • 35 citations

Two physiological agents that appear to facilitate calcium discharge from the sarcoplasmic reticulum in frog heart cells: adrenalin and ATP

1981 • 31 citations

Electrical responses of smooth muscle cells of the mouse uterus to adenosine triphosphate.

1983 • 28 citations

Block by Cs of K currenti K1 and of carbachol induced K currenti Cch in frog atrium

1983 • 25 citations

Purine receptors and guinea‐pig trachea: evidence for a direct action of ATP

1988 • 20 citations

The mechanical response of rat myometrium to adenosine triphosphate in Ca-free solution.

1987 • 14 citations

The negative chronotropic effect of adenine derivatives and acetylcholine on frog and rat hearts

1966 • 13 citations