The signal that sorts yeast cytochrome b2 to the mitochondrial intermembrane space contains three distinct functional regions.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1984 • 2,401 citations

Domain structure of mitochondrial and chloroplast targeting peptides

1989 • 1,191 citations

Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria.

1982 • 1,152 citations

A protein-conducting channel in the endoplasmic reticulum

1991 • 613 citations

The primary structure of the Saccharomyces cerevisiae gene for alcohol dehydrogenase.

1982 • 558 citations

Protein Sorting to Mitochondria: Evolutionary Conservations of Folding and Assembly

1990 • 494 citations

Two nuclear mutations that block mitochondrial protein import in yeast.

1984 • 490 citations

Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism

1992 • 422 citations

[13] Immunochemical identification of membrane proteins after sodium dodecyl sulfate—polyacrylamide gel electrophoresis

1983 • 309 citations

The first twelve amino acids (less than half of the pre-sequence) of an imported mitochondrial protein can direct mouse cytosolic dihydrofolate reductase into the yeast mitochondrial matrix.

1985 • 279 citations

Successive translocation into and out of the mitochondrial matrix: Targeting of proteins to the intermembrane space by a bipartite signal peptide

1987 • 275 citations

A novel in vitro transcription-translation system: accurate and efficient synthesis of single proteins from cloned DNA sequences.

1984 • 251 citations

Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space

1992 • 233 citations

Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria.

1982 • 220 citations

The cleavable prepiece of an imported mitochondrial protein is sufficient to direct cytosolic dihydrofolate reductase into the mitochondrial matrix

1984 • 199 citations

Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps.

1982 • 187 citations

Inner membrane protease I, an enzyme mediating intramitochondrial protein sorting in yeast.

1991 • 183 citations

Structure, expression and regulation of a nuclear gene encoding a mitochondrial protein: the yeast L(+)-lactate cytochrome c oxidoreductase (cytochrome b2).

1985 • 178 citations

Protein sorting in mitochondria

1992 • 174 citations

Sequences from a prokaryotic genome or the mouse dihydrofolate reductase gene can restore the import of a truncated precursor protein into yeast mitochondria.

1987 • 160 citations

The first twelve amino acids of a yeast mitochondrial outer membrane protein can direct a nuclear-coded cytochrome oxidase subunit to the mitochondrial inner membrane.

1985 • 140 citations

Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein

1990 • 132 citations

The cytoplasmically-made subunit IV is necessary for assembly of cytochrome c oxidase in yeast.

1985 • 120 citations

Transport of proteins to the mitochondrial intermembrane space: the ‘sorting’ domain of the cytochrome c1 presequence is a stop-transfer sequence specific for the mitochondrial inner membrane.

1987 • 117 citations

Multiple topogenic sequences in bovine opsin.

1987 • 115 citations

Dual functions of the signal peptide in protein transfer across the membrane

1985 • 90 citations

Transport of proteins to the mitochondrial intermembrane space: the ‘matrix-targeting’ and the ‘sorting’ domains in the cytochrome c1 presequence.

1987 • 84 citations

Chapter 20 Protein Import into Isolated Yeast Mitochondria

1991 • 53 citations

More than just a channel: Provocative new features of protein traffic across the ER membrane

1991 • 42 citations

Structural Requirements for Interruption of Protein Translocation across Rough Endoplasmic Reticulum Membrane1

1990 • 37 citations

Mutations in a 19-amino-acid hydrophobic region of the yeast cytochrome c1 presequence prevent sorting to the mitochondrial intermembrane space.

1992 • 30 citations

Mutations restoring import of a yeast mitochondrial protein with a nonfunctional presequence.

1988 • 24 citations

Mutations in a 19-Amino-Acid Hydrophobic Region of the Yeast Cytochrome Presequence Prevent Sorting to the Mitochondrial Intermembrane Space

1992 • 9 citations