Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

Protein kinase Cα activates RAF-1 by direct phosphorylation

1993 • 1,282 citations

Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology.

1991 • 909 citations

Crystal structure of the zeta isoform of the 14-3-3 protein

1995 • 516 citations

Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

1995 • 473 citations

Heat-shock protein hsp90 governs the activity of pp60v-src kinase.

1993 • 420 citations

Binding of 14-3-3 Proteins to the Protein Kinase Raf and Effects on Its Activation

1994 • 415 citations

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

1991 • 375 citations

Activation of Raf-1 by 14-3-3 proteins

1994 • 370 citations

14-3-3 Protein Homologs Required for the DNA Damage Checkpoint in Fission Yeast

1994 • 344 citations

Identification of the major phosphorylation sites of the Raf-1 kinase

1993 • 337 citations

Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases.

1988 • 332 citations

Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system.

1993 • 302 citations

Stimulatory Effects of Yeast and Mammalian 14-3-3 Proteins on the Raf Protein Kinase

1994 • 299 citations

Interaction of the Protein Kinase Raf-1 with 14-3-3 Proteins

1994 • 285 citations

The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family.

1993 • 266 citations

14-3-3 proteins on the MAP

1995 • 255 citations

Isoforms of 14‐3‐3 protein can form homo‐ and heterodimers in vivo and in vitro: implications for function as adapter proteins

1995 • 254 citations

14-3-3 proteins associate with cdc25 phosphatases.

1995 • 251 citations

Association of the Protein Kinases c-Bcr and Bcr-Abl with Proteins of the 14-3-3 Family

1994 • 233 citations

14-3-3 Is Not Essential for Raf-1 Function: Identification of Raf-1 Proteins That Are Biologically Activated in a 14-3-3- and Ras-Independent Manner

1995 • 217 citations

Protein kinase C inhibitor proteins

1990 • 213 citations

14-3-3: Modulators of Signaling Proteins?

1994 • 206 citations

Reversal of Raf-1 Activation by Purified and Membrane-Associated Protein Phosphatases

1995 • 202 citations

Bcr and Raf form a complex in vivo via 14-3-3 proteins.

1995 • 201 citations

Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins.

1995 • 165 citations

14-3-3 proteins: potential roles in vesicular transport and Ras signaling in Saccharomyces cerevisiae.

1995 • 165 citations

Association of Polyomavirus Middle Tumor Antigen with 14-3-3 Proteins

1994 • 162 citations

Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor beta-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach.

1993 • 154 citations

Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes

1993 • 150 citations

Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells.

1995 • 139 citations

Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos.

1993 • 120 citations

Kinetics of p56lck and p60src Src homology 2 domain binding to tyrosine-phosphorylated peptides determined by a competition assay or surface plasmon resonance.

1993 • 117 citations

Demonstration of the Phosphorylation-Dependent Interaction of Tryptophan Hydroxylase with the 14-3-3 Protein

1993 • 103 citations

Purification of a Ras-dependent Mitogen-activated Protein Kinase Kinase Kinase from Bovine Brain Cytosol and Its Identification as a Complex of B-Raf and 14-3-3 Proteins

1995 • 100 citations

Activation of protein kinase C by the 14‐3‐3 proteins homologous with Exol protein that stimulates calcium‐dependent exocytosis

1992 • 96 citations

Raf-1 interacts with Fyn and Src in a non-phosphotyrosine-dependent manner

1994 • 95 citations

Activation of Protein Kinase C by Purified Bovine Brain 14‐3‐3: Comparison with Tyrosine Hydroxylase Activation

1994 • 61 citations

Synergistic activation by Ras and 14-3-3 protein of a mitogen-activated protein kinase kinase kinase named Ras-dependent extracellular signal-regulated kinase kinase stimulator.

1994 • 55 citations

Introducing a biosensor based technology for real-time biospecific interaction analysis.

1993 • 32 citations

Regulation of Raf-1-Dependent Signaling during Early Xenopus Development

1995 • 29 citations

Reconstruction of the immunogenic peptide RNase(43-56) by identification and transfer of the critical residues into an unrelated peptide backbone.

1989 • 29 citations

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