The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

1997 • 5,665 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

SH2 domains recognize specific phosphopeptide sequences

1993 • 2,685 citations

Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL

1996 • 2,627 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

1997 • 2,245 citations

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

1997 • 1,724 citations

Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine

1996 • 1,371 citations

Mitotic and G ₂ Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

1997 • 1,332 citations

Principles of protein structure

1980 • 1,094 citations

[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations

1991 • 1,036 citations

Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology.

1991 • 909 citations

RIBBONS 2.0

1991 • 814 citations

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

1985 • 813 citations

Two Binding Orientations for Peptides to the Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions

1994 • 800 citations

Determination of the Specific Substrate Sequence Motifs of Protein Kinase C Isozymes

1997 • 557 citations

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

1994 • 519 citations

Crystal structure of the zeta isoform of the 14-3-3 protein

1995 • 516 citations

Occurrence and role ofcis peptide bonds in protein structures

1990 • 516 citations

Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

1995 • 473 citations

Binding of 14-3-3 Proteins to the Protein Kinase Raf and Effects on Its Activation

1994 • 415 citations

14-3-3 and its possible role in co-ordinating multiple signalling pathways

1996 • 367 citations

Stimulatory Effects of Yeast and Mammalian 14-3-3 Proteins on the Raf Protein Kinase

1994 • 299 citations

Interaction of the Protein Kinase Raf-1 with 14-3-3 Proteins

1994 • 285 citations

Phosphorylated nitrate reductase from spinach leaves is inhibited by 14-3-3 proteins and activated by fusicoccin

1996 • 252 citations

Protein kinase C inhibitor proteins

1990 • 213 citations

14-3-3 proteins associate with phosphorylated simple epithelial keratins during cell cycle progression and act as a solubility cofactor.

1996 • 209 citations

The complex of polyoma virus middle-T antigen and pp60c-src.

1984 • 196 citations

14-3-3 (ϵ) Interacts with the Insulin-like Growth Factor I Receptor and Insulin Receptor Substrate I in a Phosphoserine-dependent Manner

1997 • 196 citations

Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2

1996 • 193 citations

14-3-3 Proteins Associate with A20 in an Isoform-specific Manner and Function Both as Chaperone and Adapter Molecules

1996 • 181 citations

14-3-3 α and δ Are the Phosphorylated Forms of Raf-activating 14-3-3 β and ζ

1995 • 181 citations

Molecular Cloning and Expression of the Transformation Sensitive Epithelial Marker Stratifin

1993 • 177 citations

Association of Polyomavirus Middle Tumor Antigen with 14-3-3 Proteins

1994 • 162 citations

Direct Interaction between Protein Kinase Cθ (PKCθ) and 14-3-3τ in T Cells: 14-3-3 Overexpression Results in Inhibition of PKCθ Translocation and Function†

1996 • 158 citations

Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.

1994 • 153 citations

Raf-1 Kinase and Exoenzyme S Interact with 14-3-3ζ through a Common Site Involving Lysine 49

1997 • 147 citations

14-3-3 Is Phosphorylated by Casein Kinase I on Residue 233

1997 • 146 citations

Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells.

1995 • 139 citations

Serine Phosphorylation of Cbl Induced by Phorbol Ester Enhances Its Association with 14-3-3 Proteins in T Cells via a Novel Serine-rich 14-3-3-binding Motif

1997 • 135 citations

Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1.

1996 • 134 citations

Expression and Structural Analysis of 14-3-3 Proteins

1995 • 127 citations

Activation-modulated Association of 14–3–3 Proteins with Cbl in T Cells

1996 • 109 citations

Interaction of the Ligand-activated Glucocorticoid Receptor with the 14-3-3η Protein

1997 • 94 citations

Identification of regions in polyomavirus middle T and small t antigens important for association with protein phosphatase 2A

1995 • 75 citations

Post-translationally modified 14-3-3 isoforms and inhibition of protein kinase C

1995 • 67 citations

Introducing a biosensor based technology for real-time biospecific interaction analysis.

1993 • 32 citations

Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation

1996 • 31 citations