Efficiency and diversity of protein localization by random signal sequences.

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

Current topics in membranes and transport

1976 • 847 citations

KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene

1989 • 684 citations

A Possible Precursor of Immunoglobulin Light Chains

1972 • 609 citations

Protein Import into the Cell Nucleus

1986 • 544 citations

Mechanism of Protein Translocation Across the Endoplasmic Reticulum Membrane

1986 • 509 citations

S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP

1989 • 421 citations

Many Random Sequences Functionally Replace the Secretion Signal Sequence of Yeast Invertase

1987 • 375 citations

Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast

1981 • 302 citations

Mutations which alter the function of the signal sequence of the maltose binding protein of Escherichia coli

1980 • 268 citations

Use of gene fusion to study secretion of maltose-binding protein into Escherichia coli periplasm

1979 • 267 citations

The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal.

1986 • 258 citations

Subunit structure of external invertase from Saccharomyces cerevisiae.

1977 • 227 citations

Sequence analysis of mutations that prevent export of λ receptor, an Escherichia coli outer membrane protein

1980 • 195 citations

The primary structure of theSaccharomyces cerevisiaegene for 3-phosphogrycerate kinase

1982 • 175 citations

Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme.

1985 • 167 citations

Sequences from a prokaryotic genome or the mouse dihydrofolate reductase gene can restore the import of a truncated precursor protein into yeast mitochondria.

1987 • 160 citations

Precursors of three exported proteins in Escherichia coli.

1978 • 123 citations

Kinetic analysis of lamB mutants suggests the signal sequence plays multiple roles in protein export.

1986 • 107 citations

Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondria.

1984 • 102 citations

Transmission and scanning electron microscopic examination of intracellular organelles in freeze‐substituted Kloeckera and Saccharomyces cerevisiae Yeast Cells

1987 • 95 citations

Effects of signal sequence mutations on the kinetics of alkaline phosphatase export to the periplasm in Escherichia coli

1986 • 85 citations

Secretion-Defective Mutations in the Signal Sequence for Saccharomyces cerevisiae Invertase

1986 • 85 citations

Yeast carboxypeptidase Y can be translocated and glycosylated without its amino-terminal signal sequence.

1987 • 80 citations

Secretion-defective mutations in the signal sequence for Saccharomyces cerevisiae invertase.

1986 • 52 citations

Chapter 3 The Use of Genetic Techniques to Analyze Protein Export in Escherichia coli

1985 • 50 citations

Localization of acid phosphatase in protoplasts from Saccharomyces cerevisiae

1975 • 35 citations

Protein Import into the Cell Nucleus

1986 • 31 citations

Cassette Mutagenic Analysis of the Yeast Invertase Signal Peptide: Effects on Protein Translocation

1989 • 24 citations

Single-Amino-Acid Substitutions within the Signal Sequence of Yeast Prepro-α-Factor Affect Membrane Translocation

1988 • 23 citations

Mechanism of Protein Translocation Across the Endoplasmic Reticulum Membrane

1986 • 19 citations

Cassette mutagenic analysis of the yeast invertase signal peptide: effects on protein translocation.

1989 • 12 citations

Intragenic Revertants of Yeast Invertase Variants with Secretion-Defective Leader Sequences

1989 • 7 citations

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