Effects of signal sequence mutations on the kinetics of alkaline phosphatase export to the periplasm in Escherichia coli

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components.

1975 • 1,175 citations

TnphoA: a transposon probe for protein export signals.

1985 • 1,030 citations

E. coli mutant pleiotropically defective in the export of secreted proteins

1981 • 512 citations

Analysis of the regulation of Escherichia coli alkaline phosphatase synthesis using deletions and φ80 transducing phages

1975 • 489 citations

GENETIC ANALYSIS OF PROTEIN EXPORT IN ESCHERICHIA COLI K12

1985 • 432 citations

Secretion and Membrane Localization of Proteins inEscherichia Coli

1980 • 402 citations

Suppressor mutations that restore export of a protein with a defective signal sequence

1981 • 382 citations

Protein localization in E. coli: Is there a common step in the secretion of periplasmic and outer-membrane proteins?

1981 • 359 citations

Mechanism of Incorporation of Cell Envelope Proteins in Escherichia Coli

1982 • 344 citations

Mutations that alter the signal sequence of alkaline phosphatase in Escherichia coli

1983 • 281 citations

Evidence for specificity at an early step in protein export in Escherichia coli

1985 • 272 citations

Fusions of secreted proteins to alkaline phosphatase: an approach for studying protein secretion.

1985 • 238 citations

Translocation of domains of nascent periplasmic proteins across the cytoplasmic membrane is independent of elongation

1983 • 234 citations

Effects of the complete removal of basic amino acid residues from the signal peptide on secretion of lipoprotein in Escherichia coli.

1983 • 214 citations

Amino acid sequence of Escherichia coli alkaline phosphatase.

1981 • 176 citations

In vitro translocation of bacterial proteins across the plasma membrane of Escherichia coli.

1984 • 174 citations

Evidence for posttranslational translocation of β-lactamase across the bacterial inner membrane

1982 • 153 citations

Cloning and restriction mapping of the alkaline phosphatase structural gene (phoA) of Escherichia coli and generation of deletion mutants in vitro

1981 • 126 citations

Diverse effects of mutations in the signal sequence on the secretion of β-lactamase in Salmonella typhimurium

1982 • 121 citations

Signal sequence of alkaline phosphatase of Escherichia coli

1982 • 102 citations

Alkaline phosphatase and OmpA protein can be translocated posttranslationally into membrane vesicles of Escherichia coli

1985 • 98 citations

The biosynthesis of membrane-bound M13 coat protein. Energetics and assembly intermediates.

1982 • 97 citations

Sequence information within the lamB gene is required for proper routing of the bacteriophage λ receptor protein to the outer membrane of Escherichia coli K-12

1982 • 79 citations

Evidence for a coupling of synthesis and export of an outer membrane protein in Escherichia coli.

1983 • 78 citations

The lacI Gene: Its Role in lac Operon Control and Its Use as a Genetic System

1980 • 74 citations

Processing in vivo of precursor maltose-binding protein in Escherichia coli occurs post-translationally as well as co-translationally.

1981 • 73 citations

[1] Genetic analysis of protein export in Escherichia coli

1983 • 70 citations

Post-translational export of maltose-binding protein in Escherichia coli strains harboring malE signal sequence mutations and either prl+ or prl suppressor alleles.

1985 • 63 citations

Molecular components of the signal sequence that function in the initiation of protein export.

1982 • 61 citations

In vitro construction and characterization of phoA-lacZ gene fusions in Escherichia coli

1983 • 50 citations

Signal sequence mutations disrupt feedback between secretion of an exported protein and its synthesis in E. coli

1984 • 46 citations

Use of gene fusions to determine a partial signal sequence of alkaline phosphatase

1979 • 41 citations

Informational suppression of missense mutations

1975 • 36 citations

FORMATION AND LOCALIZATION OF THE ALKALINE PHOSPHATASE OF ESCHERICHIA COLI

1969 • 26 citations

Procoat, the precursor of M13 coat protein, inserts post-translationally into the membrane of cells infected by wild-type virus

1981 • 23 citations

Secretion and processing of ribose-binding protein in Escherichia coli.

1982 • 23 citations

FORMATION AND LOCALIZATION OF THE ALKALINE PHOSPHATASE OF ESCHERICHIA COLI

1969 • 21 citations

Functional implications of secondary structure analysis of wild type and mutant bacterial signal peptides.

1981 • 17 citations

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