Infection with a Helminth Parasite Prevents Experimental Colitis via a Macrophage-Mediated Mechanism

Alternative activation of macrophages

2003 • 5,952 citations

Inflammatory Bowel Disease

2002 • 3,038 citations

A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

1990 • 2,321 citations

Clinicopathologic study of dextran sulfate sodium experimental acute colitis

1998 • 1,955 citations

The Immunology of Mucosal Models of Inflammation

2002 • 1,323 citations

Experimental models of inflammatory bowel disease

1995 • 1,215 citations

Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines

1998 • 1,038 citations

Immunity, Inflammation, and Allergy in the Gut

2005 • 1,036 citations

Trichuris suis therapy in Crohn's disease

2004 • 740 citations

Trichuris suis therapy for active ulcerative colitis: A randomized controlled trial

2005 • 717 citations

Alternative Macrophage Activation Is Essential for Survival during Schistosomiasis and Downmodulates T Helper 1 Responses and Immunopathology

2004 • 714 citations

Differential Regulation of Nitric Oxide Synthase-2 and Arginase-1 by Type 1/Type 2 Cytokines In Vivo: Granulomatous Pathology Is Shaped by the Pattern of<scp>l</scp>-Arginine Metabolism

2001 • 674 citations

PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

2004 • 609 citations

Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation

2005 • 543 citations

Memory TH2 cells induce alternatively activated macrophages to mediate protection against nematode parasites

2006 • 521 citations

The immune response in autism: a new frontier for autism research

2006 • 520 citations

Concurrent enteric helminth infection modulates inflammation and gastric immune responses and reduces helicobacter-induced gastric atrophy

2000 • 508 citations

The liposome-mediated macrophage ‘suicide’ technique

1989 • 455 citations

B7-H1 Determines Accumulation and Deletion of Intrahepatic CD8+ T Lymphocytes

2004 • 375 citations

Inflammatory bowel disease

2006 • 346 citations

The IL-21 receptor augments Th2 effector function and alternative macrophage activation

2006 • 333 citations

Cutting Edge: Anti-CD25 Monoclonal Antibody Injection Results in the Functional Inactivation, Not Depletion, of CD4+CD25+ T Regulatory Cells

2006 • 333 citations

Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production

2001 • 286 citations

Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo

2005 • 283 citations

Exposure to schistosome eggs protects mice from TNBS-induced colitis

2003 • 283 citations

Heligmosomoides polygyrus inhibits established colitis in IL‐10‐deficient mice

2004 • 278 citations

Helminth Infection Protects Mice from Anaphylaxis via IL-10-Producing B Cells

2004 • 277 citations

Does the failure to acquire helminthic parasites predispose to Crohn's disease?

2000 • 266 citations

Intestinal Nematode Infection Ameliorates Experimental Colitis in Mice

2002 • 264 citations

A proof of concept study establishing Necator americanus in Crohn's patients and reservoir donors

2005 • 249 citations

A worm's eye view of the immune system: consequences for evolution of human autoimmune disease

2005 • 241 citations

Suppression of experimental colitis by intestinal mononuclear phagocytes

2006 • 232 citations

MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis

2005 • 232 citations

Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact

2000 • 219 citations

Loss of transforming growth factor β signalling in the intestine contributes to tissue injury in inflammatory bowel disease

2001 • 187 citations

Schistosoma mansoni Worms Induce Anergy of T Cells via Selective Up-Regulation of Programmed Death Ligand 1 on Macrophages

2004 • 181 citations

Concurrent infection with Schistosoma mansoni attenuates inflammation induced changes in colonic morphology, cytokine levels, and smooth muscle contractility of trinitrobenzene sulphonic acid induced colitis in rats

2003 • 168 citations

Blockade of B7-H1 Suppresses the Development of Chronic Intestinal Inflammation

2003 • 168 citations

The Schistosome Oligosaccharide Lacto-N-neotetraose Expands Gr1+ Cells That Secrete Anti-inflammatory Cytokines and Inhibit Proliferation of Naive CD4+ Cells: A Potential Mechanism for Immune Polarization in Helminth Infections

2001 • 163 citations

Peroxisome Proliferator-Activated Receptor Gamma Agonist Ligands Stimulate a Th2 Cytokine Response and Prevent Acute Colitis

2002 • 161 citations

Neutralizing Anti-IL-10 Antibody Blocks the Protective Effect of Tapeworm Infection in a Murine Model of Chemically Induced Colitis

2005 • 160 citations

Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity

2005 • 158 citations

A Schistosome-Expressed Immunomodulatory Glycoconjugate Expands Peritoneal Gr1+ Macrophages That Suppress Naive CD4+ T Cell Proliferation Via an IFN-γ and Nitric Oxide-Dependent Mechanism

2001 • 151 citations

Helminth-Modified Pulmonary Immune Response Protects Mice from Allergen-Induced Airway Hyperresponsiveness

2006 • 140 citations

Colonic lamina propria dendritic cells in mice with CD4⁺ T cell‐induced colitis

2003 • 113 citations

Tapeworm Infection Reduces Epithelial Ion Transport Abnormalities in Murine Dextran Sulfate Sodium-Induced Colitis

2001 • 111 citations

Immunopathology of schistosomiasis: a cautionary tale of mice and men

2000 • 108 citations

Role of Interleukin-10 in a Murine Model of Dextran Sulfate Sodium-Induced Colitis

1998 • 107 citations

Impairment of Alternative Macrophage Activation Delays Cutaneous Leishmaniasis in Nonhealing BALB/c Mice

2006 • 106 citations

Induction of CD8⁺regulatory T cells in the intestine byHeligmosomoides polygyrusinfection

2006 • 98 citations

Immune Regulation in the Intestine: A Balancing Act between Effector and Regulatory T Cell Responses

2004 • 86 citations

The inflammatory infiltrate in the acute stage of the dextran sulphate sodium induced colitis: B cell response differs depending on the percentage of DSS used to induce it

2001 • 77 citations

The Characterization of Intraepithelial Lymphocytes, Lamina Propria Leukocytes, and Isolated Lymphoid Follicles in the Large Intestine of Mice Infected with the Intestinal Nematode Parasite Trichuris muris

2005 • 64 citations

Role of helminths in regulating mucosal inflammation

2005 • 63 citations

Oral administration of antigens from intestinal flora anaerobic bacteria reduces the severity of experimental acute colitis in BALB/c mice

2000 • 56 citations

Regulatory T Cells in Experimental Colitis

2005 • 22 citations