Exposure to schistosome eggs protects mice from TNBS-induced colitis

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Interleukin-10 and the Interleukin-10 Receptor

2001 • 6,422 citations

Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells

1996 • 1,618 citations

Acquisition of Lymphokine-Producing Phenotype by CD4+ T Cells

1994 • 1,573 citations

Antibodies to interleukin 12 abrogate established experimental colitis in mice.

1995 • 1,338 citations

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

1996 • 1,227 citations

Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD).

1996 • 1,023 citations

Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni.

1991 • 777 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

1990 • 629 citations

Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni.

1991 • 542 citations

Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice

1997 • 422 citations

Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR)

1995 • 400 citations

Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin‐10 or antibodies to interleukin‐12

1996 • 358 citations

The Importance of Th2 Cytokines in Protective Immunity to Nematodes

1992 • 352 citations

Interleukin‐4 and interleukin‐10 synergize to inhibit cell‐mediated immunity in vivo

1993 • 341 citations

Impairment of Tetanus Toxoid-Specific Thl-like Immune Responses in Humans Infected with Schistosoma mansoni

1996 • 328 citations

Constructing polycompetitor cDNAs for quantitative PCR

1993 • 323 citations

Does the failure to acquire helminthic parasites predispose to Crohn's disease?

2000 • 266 citations

Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen.

1992 • 256 citations

Hapten-induced model of murine inflammatory bowel disease: mucosa immune responses and protection by tolerance.

1996 • 243 citations

Trends in incidence rates of ulcerative colitis and Crohn's disease

1984 • 242 citations

CD4+ Th2 response induced by Schistosoma mansoni eggs develops rapidly, through an early, transient, Th0-like stage.

1992 • 171 citations

Immune dysregulation to Ethiopian immigrants in Israel: relevance to helminth infections?

1996 • 149 citations

Modulation of murine cytokine responses to mycobacterial antigens by helminth-induced T helper 2 cell responses.

1993 • 147 citations

Schistosomiasis Mansoni in Yemeni in California: Duration of Infection, Presence of Disease, Therapeutic Management

1974 • 129 citations

IL-4 suppresses cytokine gene expression induced by IFN-gamma and/or IL-2 in murine peritoneal macrophages.

1992 • 110 citations

STAT6 Is Required for the Anti-inflammatory Activity of Interleukin-4 in Mouse Peritoneal Macrophages

1998 • 98 citations

Epidemiology of inflammatory bowel disease among U.S. Military veterans

1991 • 97 citations

Granuloma T lymphocytes in murine schistosomiasis mansoni have somatostatin receptors and respond to somatostatin with decreased IFN-gamma secretion.

1992 • 97 citations

Regulation of T cell-dependent and -independent IL-12 production by the three Th2-type cytokines IL-10, IL-6, and IL-4

1997 • 94 citations

IL-4-induced expression of the IL-1 receptor antagonist gene is mediated by STAT6.

1996 • 88 citations

Methods Used to Study Immunoregulation of Schistosome Egg Granulomas

1996 • 51 citations

PROLONGATION OF RAT KIDNEY ALLOGRAFT SURVIVAL BY NEMATODES1,2

1996 • 42 citations

Helminthic diseases endemic in the United States.

1974 • 42 citations

Inhibition of cell-mediated immunity by IL4 and IL10

1993 • 42 citations

Intestinal Nematodes in the United States

1977 • 30 citations