Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

ALSCRIPT: a tool to format multiple sequence alignments

1993 • 1,125 citations

Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization

1996 • 873 citations

Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton

1997 • 802 citations

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

1998 • 656 citations

The 2.2 Å crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with RaplA and a GTP analogue

1995 • 627 citations

A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases

1995 • 625 citations

Methods for Measurement of Intermolecular NOEs by Multinuclear NMR Spectroscopy: Application to a Bacteriophage λ N-Peptide/boxB RNA Complex

1997 • 601 citations

Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from β-spectrin 1 1Edited by P. E. Wright

1997 • 427 citations

Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott–Aldrich syndrome

1996 • 397 citations

Structural Basis of Rab Effector Specificity

1999 • 347 citations

Structure of Cdc42 in complex with the GTPase-binding domain of the ‘Wiskott–Aldrich syndrome’ protein

1999 • 319 citations

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

1993 • 319 citations

Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

1999 • 308 citations

Emerging from the Pak: the p21-activated protein kinase family

1997 • 285 citations

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

1997 • 252 citations

Structural basis for the interaction of Ras with RaIGDS

1998 • 251 citations

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

1997 • 192 citations

Increasing Complexity of Ras Signal Transduction: Involvement of Rho Family Proteins

1997 • 185 citations

The Cdc42/Rac Interactive Binding Region Motif of the Wiskott Aldrich Syndrome Protein (WASP) Is Necessary but Not Sufficient for Tight Binding to Cdc42 and Structure Formation

1998 • 143 citations

Delineation of the Cdc42/Rac-Binding Domain of p21-Activated Kinase

1998 • 139 citations

Rac Binding to p67

1997 • 135 citations

Rac GTPase interacts with GAPs and target proteins through multiple effector sites.

1995 • 126 citations

Cloning and Characterization of a Novel Cdc42-associated Tyrosine Kinase, ACK-2, from Bovine Brain

1997 • 104 citations

Definition of the Switch Surface in the Solution Structure of Cdc42Hs^,

1997 • 82 citations

Mutational Analysis of Novel Effector Domains in Rac1 Involved in the Activation of Nicotinamide Adenine Dinucleotide Phosphate (Reduced) Oxidase

1998 • 60 citations

Use of a Fluorescence Spectroscopic Readout To Characterize the Interactions of Cdc42Hs with Its Target/Effector, mPAK-3

1997 • 34 citations

Identification of the Binding Surface on Cdc42Hs for p21-Activated Kinase

1998 • 31 citations