Structure of Cdc42 in complex with the GTPase-binding domain of the ‘Wiskott–Aldrich syndrome’ protein

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR

1996 • 5,190 citations

Protein backbone angle restraints from searching a database for chemical shift and sequence homology.

1999 • 2,966 citations

Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization

1996 • 873 citations

RIBBONS 2.0

1991 • 814 citations

Membrane and Morphological Changes in Apoptotic Cells Regulated by Caspase-Mediated Activation of PAK2

1997 • 742 citations

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

1998 • 656 citations

The 2.2 Å crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with RaplA and a GTP analogue

1995 • 627 citations

A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases

1995 • 625 citations

Rac and Cdc42 Induce Actin Polymerization and G1 Cell Cycle Progression Independently of p65PAK and the JNK/SAPK MAP Kinase Cascade

1996 • 571 citations

A Suite of Triple Resonance NMR Experiments for the Backbone Assignment of 15N, 13C, 2H Labeled Proteins with High Sensitivity

1994 • 489 citations

Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from β-spectrin 1 1Edited by P. E. Wright

1997 • 427 citations

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

1993 • 319 citations

A Novel Regulator of p21-activated Kinases

1998 • 313 citations

Myotonic Dystrophy Kinase-Related Cdc42-Binding Kinase Acts as a Cdc42 Effector in Promoting Cytoskeletal Reorganization

1998 • 269 citations

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

1996 • 253 citations

Structural basis for the interaction of Ras with RaIGDS

1998 • 251 citations

Production and Incorporation of ¹⁵N, ¹³C, ²H (¹H-δ1 Methyl) Isoleucine into Proteins for Multidimensional NMR Studies

1997 • 246 citations

Crystal Structure of Human RhoA in a Dominantly Active Form Complexed with a GTP Analogue

1998 • 214 citations

Ras/Rap effector specificity determined by charge reversal

1996 • 214 citations

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

1997 • 192 citations

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

1999 • 162 citations

Wiskott–Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases

1996 • 154 citations

The Cdc42/Rac Interactive Binding Region Motif of the Wiskott Aldrich Syndrome Protein (WASP) Is Necessary but Not Sufficient for Tight Binding to Cdc42 and Structure Formation

1998 • 143 citations

Rac GTPase interacts with GAPs and target proteins through multiple effector sites.

1995 • 126 citations

An (H)C(CO)NH-TOCSY pulse scheme for sequential assignment of protonated methyl groups in otherwise deuterated 15N, 13C-labeled proteins

1996 • 84 citations

Definition of the Switch Surface in the Solution Structure of Cdc42Hs^,

1997 • 82 citations

Use of a Fluorescence Spectroscopic Readout To Characterize the Interactions of Cdc42Hs with Its Target/Effector, mPAK-3

1997 • 34 citations

Identification of the Binding Surface on Cdc42Hs for p21-Activated Kinase

1998 • 31 citations