Mutational Analysis of Novel Effector Domains in Rac1 Involved in the Activation of Nicotinamide Adenine Dinucleotide Phosphate (Reduced) Oxidase

Current protocols in molecular biology

1988 • 4,543 citations

The biochemical basis of the NADPH oxidase of phagocytes

1993 • 631 citations

The superoxide‐generating oxidase of phagocytic cells

1991 • 564 citations

The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding.

1982 • 542 citations

Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins

1996 • 534 citations

Activation of NADPH-dependent superoxide production in a cell-free system by sodium dodecyl sulfate.

1985 • 356 citations

Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558.

1994 • 260 citations

Inhibition of NADPH Oxidase Activation by 4-(2-Aminoethyl)-benzenesulfonyl Fluoride and Related Compounds

1997 • 196 citations

Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride. Evidence for participation of a pertussis and cholera toxin-insensitive G protein.

1987 • 188 citations

Regulation of the superoxide-generating NADPH oxidase by a small GTP-binding protein and its stimulatory and inhibitory GDP/GTP exchange proteins.

1992 • 159 citations

Mechanisms of NADPH oxidase activation: translocation of p40phox, Rac1 and Rac2 from the cytosol to the membranes in human neutrophils lacking p47phox or p67phox

1996 • 138 citations

Rac Binding to p67

1997 • 135 citations

Rac GTPase interacts with GAPs and target proteins through multiple effector sites.

1995 • 126 citations

Membrane Association of Rac Is Required for High Activity of the Respiratory Burst Oxidase

1996 • 116 citations

The Rac Target NADPH Oxidase p67 Interacts Preferentially with Rac2 Rather Than Rac1

1996 • 110 citations

The membrane-associated component of the amphiphile-activated, cytosol-dependent superoxide-forming NADPH oxidase of macrophages is identical to cytochrome b559.

1991 • 106 citations

Identification of the ral and rac1 Gene Products, Low Molecular Mass GTP-binding Proteins from Human Platelets

1989 • 100 citations

A new family of peptidyl-prolyl isomerases

1995 • 95 citations

Dissociation of Rac translocation from p47phox/p67phox movements in human neutrophils by tyrosine kinase inhibitors

1995 • 93 citations

Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils

1986 • 92 citations

A 68-kDa Kinase and NADPH Oxidase Component p67 Are Targets for Cdc42Hs and Rac1 in Neutrophils

1995 • 80 citations

Characterization of the Effector-specifying Domain of Rac Involved in NADPH Oxidase Activation

1995 • 74 citations

Subclass-specific sequence motifs identified in Rab GTPases

1995 • 58 citations

Guanine nucleotide binding properties of rap1 purified from human neutrophils

1990 • 53 citations

Mechanisms of NADPH oxidase activation in human neutrophils: p67phox is required for the translocation of rac 1 but not of rac 2 from cytosol to the membranes

1995 • 50 citations

Role of the rac1 p21‐GDP‐dissociation inhibitor for rho heterodimer in the activation of the superoxide‐forming NADPH oxidase of macrophages

1993 • 49 citations

Two Distinct Regions of Ras Participate in Functional Interaction with GDP‐GTP Exchangers

1995 • 21 citations