Constitutive expression of steel factor gene by human stromal cells

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

1989 • 2,045 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Quantitation of mRNA by the polymerase chain reaction.

1989 • 1,648 citations

Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction.

1990 • 1,484 citations

A Method for Isolation of Intact, Translationally Active Ribonucleic Acid

1983 • 1,469 citations

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.

1988 • 1,039 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

1990 • 870 citations

Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens.

1980 • 850 citations

Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β

1989 • 785 citations

Primary structure and functional expression of rat and human stem cell factor DNAs

1990 • 779 citations

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant

1991 • 740 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

1988 • 727 citations

IL-1 stimulates IL-6 production in endothelial cells.

1989 • 541 citations

Embryonic expression of a haematopoietic growth factor encoded by the SI locus and the ligand for c-kit

1990 • 521 citations

AMPLIFICATION OF RNA

1990 • 486 citations

Requirement for mast cell growth factor for primordial germ cell survival in culture

1991 • 482 citations

Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor

1990 • 468 citations

Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene.

1988 • 462 citations

Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and epo to stimulate human progenitor cells of the myeloid and erythroid lineages.

1991 • 454 citations

Induction of mast cell proliferation, maturation, and heparin synthesis by the rat c-kit ligand, stem cell factor.

1991 • 424 citations

Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species.

1987 • 418 citations

Inducible cell adhesion molecule 110 (INCAM-110) is an endothelial receptor for lymphocytes. A CD11/CD18-independent adhesion mechanism.

1990 • 408 citations

Effects of the steel gene product on mouse primordial germ cells in culture

1991 • 405 citations

Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.

1986 • 396 citations

Embryonic RNA expression patterns of the c-kit receptor and its cognate ligand suggest multiple functional roles in mouse development.

1991 • 346 citations

Recombinant human stem cell factor enhances the formation of colonies by CD34+ and CD34+lin- cells, and the generation of colony-forming cell progeny from CD34+lin- cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor

1991 • 341 citations

Human cutaneous T cell lymphoma and leukemia cell lines produce and respond to T cell growth factor

1981 • 340 citations

Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2.

1992 • 320 citations

Support of human hematopoiesis in long-term bone marrow cultures by murine stromal cells selectively expressing the membrane-bound and secreted forms of the human homolog of the steel gene product, stem cell factor.

1992 • 306 citations

Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains.

1991 • 300 citations

The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. Analysis by anatomical distribution, histochemistry, and protease phenotype.

1991 • 288 citations

IL-4 acts synergistically with IL-1 beta to promote lymphocyte adhesion to microvascular endothelium by induction of vascular cell adhesion molecule-1.

1990 • 286 citations

Characterization of a new megakaryocytic cell line: the Dami cell

1988 • 286 citations

Interleukin 1 induces interleukin 1. II. Recombinant human interleukin 1 induces interleukin 1 production by adult human vascular endothelial cells.

1987 • 279 citations

Vascular endothelial cells and granulopoiesis: interleukin-1 stimulates release of G-CSF and GM-CSF

1988 • 277 citations

Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase.

1991 • 265 citations

Interleukin 1 stimulates human endothelial cells to produce granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor.

1987 • 259 citations

Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer.

1991 • 258 citations

Endothelial leukocyte adhesion molecule-1 and intercellular adhesion molecule-1 mediate the adhesion of eosinophils to endothelial cells in vitro and are expressed by endothelium in allergic cutaneous inflammation in vivo.

1991 • 256 citations

Human CSF-1: gene structure and alternative splicing of mRNA precursors.

1987 • 238 citations

Structure and chromosomal location of the gene for endothelial-leukocyte adhesion molecule 1

1991 • 192 citations

Growth of normal human keratinocytes and fibroblasts in serum‐free medium is stimulated by acidic and basic fibroblast growth factor

1989 • 174 citations

Nucleotide sequence of the human γ cytoskeletal actin mRNA: anomalous evolution of vertebrate non-muscle actin genes

1986 • 161 citations

Human herpesvirus-6 in human lymphomas: identification of specific sequences in Hodgkin's lymphomas by polymerase chain reaction

1991 • 158 citations

Direct stimulation of cells expressing receptors for macrophage colony- stimulating factor (CSF-1) by a plasma membrane-bound precursor of human CSF-1

1990 • 150 citations

Adult human vascular endothelial cells express the IL6 gene differentially in response to LPS or IL1

1989 • 147 citations

Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells

1992 • 140 citations

Expression of the mRNA for the ligand of C-kit in mouse sertoli cells

1991 • 130 citations

Human macrophage-colony stimulating factor: Alternative RNA and protein processing from a single gene

1988 • 128 citations

Transcriptional and posttranscriptional modulation of myeloid colony-stimulating factor expression by tumor necrosis factor and other agents.

1988 • 124 citations

Necessity of extracellular domain of W (c-kit) receptors for attachment of murine cultured mast cells to fibroblasts

1992 • 115 citations

Enhancement of murine blast cell colony formation in culture by recombinant rat stem cell factor, ligand for c-kit

1991 • 113 citations

Interactions among colony-stimulating factors, IL-1 beta, IL-6, and kit-ligand in the regulation of primitive murine hematopoietic cells.

1992 • 104 citations

Differential Processing of Colony-Stimulating Factor 1 Precursors Encoded by Two Human cDNAs

1988 • 103 citations

Overcoming interference to retroviral superinfection results in amplified expression and transmission of cloned genes.

1988 • 97 citations

Effects of Tumour Necrosis Factor and Related Cytokines on Vascular Endothelial Cells

2007 • 97 citations

Activation of erythropoietin receptors by Friend viral gp55 and by erythropoietin and down-modulation by the murine Fv-2r resistance gene.

1990 • 90 citations

Expression of stem cell factor and c-kit mRNA in cultured endothelial cells, monocytes and cloned human bone marrow stromal cells (CFU-RF).

1992 • 88 citations

Ping-pong amplification of a retroviral vector achieves high-level gene expression: human growth hormone production

1990 • 88 citations

Interleukin 1 stimulates endothelial cells to release multilineage human colony-stimulating activity.

1987 • 87 citations

Interaction of human bone marrow fibroblasts with megakaryocytes: role of the c-kit ligand

1992 • 86 citations

A simplified method for determination of specific DNA or RNA copy number using quantitative PCR and an automatic DNA sequencer.

1992 • 80 citations

The c-fms gene complements the mitogenic defect in mast cells derived from mutant W mice but not mi (microphthalmia) mice.

1991 • 69 citations

An analysis of the multilineage production of human hematopoietic progenitors in long-term bone marrow culture: evidence that reactive oxygen intermediates derived from mature phagocytic cells have a role in limiting progenitor cell self-renewal

1988 • 67 citations

Interleukin 1 and poly(rI).poly(rC) induce production of granulocyte CSF, macrophage CSF, and granulocyte-macrophage CSF by human endothelial cells.

1989 • 67 citations

Interleukin-1 induces human bone marrow-derived fibroblasts to produce multilineage hematopoietic growth factors.

1987 • 61 citations

Proteolytic processing of a plasma membrane-bound precursor to human macrophage colony-stimulating factor (CSF-1) is accelerated by phorbol ester.

1991 • 38 citations

Adhesion of mouse mast cells to fibroblasts: Adverse effects of steel (SI) mutation

1991 • 37 citations

Specific repression of granulocyte-macrophage and granulocyte colony- stimulating factor gene expression in interleukin-1-stimulated endothelial cells with antisense oligodeoxynucleotides

1992 • 27 citations

Erythroid burst-promoting activity produced by interleukin-1-stimulated endothelial cells is granulocyte-macrophage colony-stimulating factor

1988 • 26 citations

Detection and quantitation of long-term culture-initiating cells in normal human peripheral blood.

1992 • 26 citations

Diagnosis of thalassemia using cDNA amplification of circulating erythroid cell mRNA with the polymerase chain reaction [published erratum appears in Blood 1992 Jun 15;79(12):3397]

1991 • 20 citations

Macrophage growth and stimulating factor, M-CSF.

1990 • 19 citations

Vascular endothelial cells and hematopoiesis: regulation of gene expression in human vascular endothelial cells.

1991 • 18 citations

Membrane bound forms of human macrophage colony stimulating factor (M-CSF, CSF-1).

1990 • 16 citations

Retrovirus Receptors and their Genetics

1981 • 12 citations

Interleukin-1 stimulation stabilizes GM-CSF mRNA in human vascular endothelial cells: preliminary studies on the role of the 3' AU rich motif.

1990 • 12 citations