Necessity of extracellular domain of W (c-kit) receptors for attachment of murine cultured mast cells to fibroblasts

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1978 • 846 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

Expression and function of c-kit in hemopoietic progenitor cells.

1991 • 756 citations

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant

1991 • 740 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity

1983 • 702 citations

A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family

1986 • 647 citations

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

1990 • 632 citations

Interleukin 10: a novel stimulatory factor for mast cells and their progenitors.

1991 • 514 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.

1989 • 495 citations

Heterogeneity of Mast Cells and Phenotypic Change Between Subpopulations

1989 • 484 citations

In utero manipulation of coat color formation by a monoclonal anti-c-kit antibody: two distinct waves of c-kit-dependency during melanocyte development.

1991 • 479 citations

Transmembrane TGF-α precursors activate EGF/TGF-α receptors

1989 • 432 citations

The coat colours of mice. A model for mammalian gene action and interaction.

1979 • 401 citations

Decreased production of mast cells in S1/S1d anemic mice

1979 • 372 citations

W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor.

1990 • 349 citations

The Dominant W ⁴² Spotting Phenotype Results from a Missense Mutation in the c- kit Receptor Kinase

1990 • 287 citations

Interleukin 4 as an essential factor for in vitro clonal growth of murine connective tissue-type mast cells.

1987 • 268 citations

Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase.

1991 • 265 citations

The persisting (P) cell: histamine content, regulation by a T cell-derived factor, origin from a bone marrow precursor, and relationship to mast cells.

1981 • 234 citations

The Coat Colors of Mice. A Model for Mammalian Gene Action and Interaction

1980 • 158 citations

Clonal assay of mouse mast cell colonies in methylcellulose culture

1982 • 155 citations

Characterization of a murine lymphokine distinct from interleukin 2 and interleukin 3 (IL-3) possessing a T-cell growth factor activity and a mast-cell growth factor activity that synergizes with IL-3.

1986 • 147 citations

Fibroblasts maintain the phenotype and viability of the rat heparin-containing mast cell in vitro.

1985 • 140 citations

Thiol-sensitive mast cell lines derived from mouse bone marrow respond to a mast cell growth-enhancing activity different from both IL-3 and IL-4.

1989 • 93 citations

Fibroblast‐dependent growth of mouse mast cells in vitro: Duplication of mast cell depletion in mutant mice of w/w^v genotype

1988 • 81 citations

The mast cell-committed progenitor. I. Description of a cell capable of IL-3-independent proliferation and differentiation without contact with fibroblasts.

1989 • 50 citations

CHANGED DIFFERENTIATION PATTERN OF PARENTAL COLONY-FORMING CELLS IN F1 HYBRID MICE SUFFERING FROM GRAFT-VERSUS-HOST DISEASE

1970 • 50 citations

Proliferation and differentiation in culture of mast cell progenitors derived from mast cell‐deficient mice of genotype W/W^v

1985 • 46 citations

Effect of W and Wυ alleles on production of tissue mast cells in mice

1980 • 45 citations

Purification of MEA, a mast cell growth-enhancing activity, to apparent homogeneity and its partial amino acid sequencing.

1990 • 39 citations

Adhesion of mouse mast cells to fibroblasts: Adverse effects of steel (SI) mutation

1991 • 37 citations

The mast cell-committed progenitor. II. W/Wv mice do not make mast cell-committed progenitors and S1/S1d fibroblasts do not support development of normal mast cell-committed progenitors.

1989 • 29 citations

Suppressive effect of Sl/Sld mouse embryo-derived fibroblast cell lines on diffusible factor-dependent proliferation of mast cells

1989 • 16 citations

Osteoblast-like cell line maintains in vitro rat peritoneal mast cell viability and functional activity.

1990 • 12 citations

Regulation of mast cell differentiation studied using the diffusion chamber technique.

1990 • 4 citations

Suppressive effect of Sl/Sld mouse embryo-derived fibroblast cell lines on diffusible factor-dependent proliferation of mast cells

1989 • 3 citations