Expression of Dual TCR on DO11.10 T Cells Allows for Ovalbumin-Induced Oral Tolerance to Prevent T Cell-Mediated Colitis Directed against Unrelated Enteric Bacterial Antigens

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

Inflammatory Bowel Disease

2002 • 3,038 citations

Induction by Antigen of Intrathymic Apoptosis of CD4 ⁺ CD8 ⁺ TCR ^lo Thymocytes in Vivo

1990 • 1,781 citations

The Immunology of Mucosal Models of Inflammation

2002 • 1,323 citations

Inflammatory Bowel Disease

1991 • 1,264 citations

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

1996 • 1,227 citations

Phenotypically distinct subsets of CD4⁺ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

1993 • 1,064 citations

Regulatory T Cells Selectively Express Toll-like Receptors and Are Activated by Lipopolysaccharide

2003 • 976 citations

CD4+CD25+ TR Cells Suppress Innate Immune Pathology Through Cytokine-dependent Mechanisms

2003 • 748 citations

The role of Th1/Th2 polarization in mucosal immunity

2002 • 613 citations

High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

1994 • 544 citations

Expression of Two T Cell Receptor α Chains: Dual Receptor T Cells

1993 • 527 citations

Activation of CD25+CD4+ Regulatory T Cells by Oral Antigen Administration

2001 • 458 citations

Generation of Anergic and Potentially Immunoregulatory CD25+CD4 T Cells In Vivo After Induction of Peripheral Tolerance with Intravenous or Oral Antigen

2001 • 429 citations

CD4+ T Cells Reactive to Enteric Bacterial Antigens in Spontaneously Colitic C3H/HeJBir Mice: Increased T Helper Cell Type 1 Response and Ability to Transfer Disease

1998 • 393 citations

Exclusion and inclusion of α and β T cell receptor alleles

1992 • 346 citations

Bacteria-triggered CD4+ T Regulatory Cells Suppress Helicobacter hepaticus–induced Colitis

2002 • 324 citations

Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients.

1997 • 320 citations

Regulatory T cells and inflammatory bowel disease

1999 • 270 citations

Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes.

1993 • 247 citations

Inflammatory bowel disease in C.B-17 scid mice reconstituted with the CD45RBhigh subset of CD4+ T cells.

1996 • 180 citations

Regulatory CD4 T Cells Control the Size of the Peripheral Activated/Memory CD4 T Cell Compartment

2000 • 153 citations

Colitis in transgenic and knockout animals as models of human inflammatory bowel disease

1999 • 151 citations

T Helper 1 and T Helper 2 Cells Are Pathogenic in an Antigen-specific Model of Colitis

2002 • 142 citations

Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion.

1995 • 132 citations

Dual receptor T cells extend the immune repertoire for foreign antigens

2002 • 121 citations

Repertoire Requirements of CD4+ T Cells That Prevent Spontaneous Autoimmune Encephalomyelitis

2000 • 97 citations

Enteric bacterial antigens activate CD4+ T cells fromscid mice with inflammatory bowel disease

2001 • 90 citations

Memory T cell development in the absence of specific antigen priming.

1996 • 83 citations

Dual T cell receptor alpha chain T cells in autoimmunity.

1995 • 82 citations

Increased frequency of abnormal gamma delta T cells in blood of patients with inflammatory bowel diseases.

1996 • 58 citations

Functional differentiation of T cells in the intestine of T cell receptor transgenic mice

1997 • 51 citations

T-cell receptor alpha chain plays a critical role in antigen-specific suppressor cell function.

1991 • 51 citations

Limited CD4 T-cell diversity associated with colitis in T-cell receptor α mutant mice requires a T helper 2 environment

2000 • 44 citations

Antigen-induced mucosal T cell activation is followed by Th1 T cell suppression in continuously fed ovalbumin TCR-transgenic mice

2000 • 44 citations

Memory/effector T cells in TCR transgenic mice develop via recognition of enteric antigens by a second, endogenous TCR

1999 • 39 citations

Dual Receptor T‐Cells

1995 • 34 citations

TCR-Mediated Involvement of CD4+ Transgenic T Cells in Spontaneous Inflammatory Bowel Disease in Lymphopenic Mice

1999 • 29 citations

Triggering a Second T Cell Receptor on Diabetogenic T Cells Can Prevent Induction of Diabetes

1999 • 27 citations

Somatic generation of antigen-receptor diversity: a reprise

2001 • 17 citations

Dual TCR-Expressing T Lymphocytes in Health and Disease

2001 • 17 citations