Dual Receptor T‐Cells

The clonal selection theory of acquired immunity

1959 • 1,576 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

1991 • 1,187 citations

Negative selection of lymphocytes

1994 • 810 citations

Naive and memory T cells show distinct pathways of lymphocyte recirculation.

1990 • 792 citations

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: Role of anti-self (virus) immune response

1991 • 766 citations

Positive selection of lymphocytes

1994 • 563 citations

Expression of Two T Cell Receptor α Chains: Dual Receptor T Cells

1993 • 527 citations

The Molecular Basis of Allorecognition

1993 • 398 citations

In transgenic mice the introduced functional T cell receptor β gene prevents expression of endogenous β genes

1988 • 374 citations

Exclusion and inclusion of α and β T cell receptor alleles

1992 • 346 citations

T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire.

1991 • 323 citations

Regulation of TCR α and β gene allelic exclusion during T-cell development

1992 • 284 citations

Genetic and Mutational Analysis of the T-Cell Antigen Receptor

1990 • 275 citations

Thymocyte Expression of RAG-1 and RAG-2: Termination by T Cell Receptor Cross-Linking

1991 • 270 citations

A T cell clone expresses two T cell receptor α genes but uses one αβ heterodimer for allorecognition and self MHC-restricted antigen recognition

1988 • 200 citations

Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression.

1992 • 152 citations

Preferential V beta gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility complex recognition.

1992 • 150 citations

Recognition by Class II Alloreactive T Cells of Processed Determinants from Human Serum Proteins

1991 • 72 citations

Each of the two productive T cell receptor α-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an α chain which can contribute to the constitution of a surface-expressed αβ dimer

1991 • 59 citations

Marked differences in the efficiency of expression of distinct alphabeta T cell receptor heterodimers

1990 • 57 citations

Analysis of specificity for antigen, Mls, and allogeneic MHC by transfer of T-cell receptor α- and β-chain genes

1988 • 52 citations

Marked differences in the efficiency of expression of distinct alpha beta T cell receptor heterodimers.

1989 • 49 citations

Post-translational attainment of allelic exclusion of the T cell receptor α chain in a T cell clone

1991 • 43 citations

Post-transcriptional allelic exclusion of two functionally rearranged T cell receptor α genes

1989 • 29 citations