Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility complex class I molecules into the medial-Golgi compartment.

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Expression of wild-type and mutant forms of influenza hemagglutinin: The role of folding in intracellular transport

1986 • 879 citations

Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaques.

1985 • 789 citations

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1990 • 717 citations

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1990 • 644 citations

Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells

1983 • 586 citations

Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum

1989 • 499 citations

Assembly of MHC class I molecules analyzed in vitro

1990 • 491 citations

Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens

1988 • 470 citations

Cellular peptide composition governed by major histocompatibility complex class I molecules

1990 • 438 citations

Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro

1990 • 418 citations

Assembly of influenza hemagglutinin trimers and its role in intracellular transport.

1986 • 413 citations

An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens

1985 • 405 citations

Use of endo- and exoglycosidases for structural studies of glycoconjugates

1979 • 398 citations

Second proteasome-related gene in the human MHC class II region

1991 • 348 citations

A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes

1989 • 339 citations

Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis

1991 • 336 citations

Brefeldin A Specifically Inhibits Presentation of Protein Antigens to Cytotoxic T Lymphocytes

1989 • 329 citations

Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter

1991 • 329 citations

Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance

1985 • 322 citations

Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation

1989 • 317 citations

Participation of a novel 88-kD protein in the biogenesis of murine class I histocompatibility molecules.

1991 • 312 citations

Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein

1991 • 303 citations

Subunit of the '20S' proteasome (multicatalytic proteinase) encoded by the major histocompatibility complex

1991 • 262 citations

Homology of proteasome subunits to a major histocompatibility complex-linked LMP gene

1991 • 256 citations

A complex between the MHC class I homologue encoded by human cytomegalovirus and β2 microglobulin

1990 • 246 citations

Peptide-induced conformational change of the class I heavy chain

1991 • 221 citations

Endogenously synthesized peptide with an endoplasmic reticulum signal sequence sensitizes antigen processing mutant cells to class I-restricted cell-mediated lysis.

1991 • 215 citations

Defective Presentation of Endogenous Antigen by a Cell Line Expressing Class I Molecules

1990 • 202 citations

A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecules

1991 • 188 citations

A Golgi retention signal in a membrane-spanning domain of coronavirus E1 protein.

1991 • 185 citations

Protein sorting by selective retention in the endoplasmic reticulum and Golgi stack

1987 • 179 citations

Peptide ligand-induced conformation and surface expression of the Ld class I MHC molecule

1990 • 155 citations

H-2Kd-restricted antigenic peptides share a simple binding motif.

1991 • 145 citations

Sequence and structural organization of murine cytomegalovirus immediate-early gene 1

1987 • 141 citations

Protection against lethal cytomegalovirus infection by a recombinant vaccine containing a single nonameric T-cell epitope

1991 • 135 citations

Molecular cloning and physical mapping of murine cytomegalovirus DNA

1983 • 134 citations

Cellular and Molecular Basis of the Protective Immune Response to Cytomegalovirus Infection

1990 • 134 citations

Modulation of MHC antigen expression by viruses and oncogenes

1991 • 128 citations

Structural organization, expression, and functional characterization of the murine cytomegalovirus immediate-early gene 3

1992 • 123 citations

The specific binding of peptide ligand to Ld class I major histocompatibility complex molecules determines their antigenic structure.

1991 • 122 citations

Selectively increased production of interferon-gamma by subsets of Lyt-2+ and L3T4+ T cells identified by expression of Pgp-1.

1987 • 120 citations

Presentation of CMV immediate-early antigen to cytolytic T lymphocytes is selectively prevented by viral genes expressed in the early phase

1989 • 115 citations

Biosynthesis and cell surface localization of nonglycosylated human histocompatibility antigens.

1981 • 113 citations

Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation.

1991 • 105 citations

An adenovirus glycoprotein binds heavy chains of class I transplantation antigens from man and mouse

1982 • 99 citations

Insertional mutagenesis of the murine cytomegalovirus genome: One prominent α gene (ie2) is dispensable for growth

1988 • 95 citations

ATP is required for in vitro assembly of MHC class I antigens but not to transfer of peptides acrosss the ER membrane

1991 • 92 citations

Post-Transcriptional Control of Class I MHC mRNA Expression in Adenovirus 12-Transformed Cells

1987 • 79 citations

Cytolytic T lymphocyte recognition of the murine cytomegalovirus nonstructural immediate-early protein pp89 expressed by recombinant vaccinia virus.

1987 • 77 citations

Cytomegalovirus Strain AD169 Binds beta2 Microglobulin in Vitro after Release from Cells

1987 • 77 citations

Mutation in a new H-2-associated histocompatibility gene closely linked to H-2D.

1977 • 71 citations

Slower processing, weaker beta 2-M association, and lower surface expression of H-2Ld are influenced by its amino terminus.

1986 • 69 citations

Structure and expression of murine cytomegalovirus immediate-early gene 2

1991 • 67 citations

A nucleoprotein peptide of influenza A virus stimulates assembly of HLA-B27 class I heavy chains and β2-micro-globulin translated in vitro

1990 • 60 citations

Insertional mutagenesis of the murine cytomegalovirus genome: one prominent alpha gene (ie2) is dispensable for growth.

1988 • 59 citations

Protein-specific cytotoxic T lymphocytes. Recognition of transfectants expressing intracellular, membrane-associated or secreted forms of β-galactosidase

1989 • 59 citations

T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes.

1987 • 52 citations

Intracellular transport of class I histocompatibility molecules. Influence of protein folding on transport to the cell surface.

1988 • 42 citations