Mice Lacking Mature T and B Lymphocytes Develop Arthritic Lesions after Immunization with Type II Collagen

ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS

1996 • 2,527 citations

Autoimmunity to type II collagen an experimental model of arthritis.

1977 • 1,599 citations

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis.

1992 • 1,002 citations

The Discoidin Domain Receptor Tyrosine Kinases Are Activated by Collagen

1997 • 956 citations

Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates.

1981 • 705 citations

Interleukin 6 Is Required for the Development of Collagen-induced Arthritis

1998 • 605 citations

Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice.

1996 • 602 citations

An Orphan Receptor Tyrosine Kinase Family Whose Members Serve as Nonintegrin Collagen Receptors

1997 • 510 citations

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice.

1994 • 426 citations

Structural studies on cartilage collagen employing limited cleavage and solubilization with pepsin

1972 • 420 citations

Serum transfer of collagen-induced arthritis in mice.

1983 • 414 citations

Induction of arthritis with monoclonal antibodies to collagen.

1992 • 382 citations

Type II collagen-induced arthritis in rats. Passive transfer with serum and evidence that IgG anticollagen antibodies can cause arthritis.

1982 • 339 citations

B cell-deficient mice do not develop type II collagen-induced arthritis (CIA)

1998 • 320 citations

Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids.

1989 • 320 citations

Relationship between Th1/Th2 cytokine patterns and the arthritogenic response in collagen‐induced arthritis

1996 • 317 citations

T Lymphocytes in Collagen II‐Induced Arthritis in Mice

1985 • 253 citations

Nature of the collagen synthesized by a transplanted chondrosarcoma

1975 • 248 citations

In vitro differentiation of human monocytes. Differences in monocyte phenotypes induced by cultivation on glass or on collagen.

1982 • 225 citations

Collagen-induced Arthritis Is Reduced in 5-Lipoxygenase-activating Protein-deficient Mice

1997 • 221 citations

Genetic susceptibility to murine collagen II autoimmune arthritis. Proposed relationship to the IgG2 autoantibody subclass response, complement C5, major histocompatibility complex (MHC) and non-MHC loci.

1985 • 210 citations

Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type 1 (TNFR1)-IgG1-treated and TNFR1-deficient mice.

1996 • 203 citations

Reduced incidence and severity of collagen‐induced arthritis in interleukin‐12‐deficient mice

1996 • 180 citations

Beneficial effects of tumour necrosis factor-alpha (TNF-α) blockade in rheumatoid arthritis (RA)

1995 • 132 citations

Reduced Incidence and Severity of Antigen-induced Autoimmune Diseases in Mice Lacking Interferon Regulatory Factor-1

1997 • 131 citations

Arthritis in DBA/1 Mice Induced with Passively Transferred Type II Collagen Immune Serum

1990 • 126 citations

Collagen-induced arthritis in CD4- or CD8-deficient mice: CD8+ T cells play a role in initiation and regulate recovery phase of collagen-induced arthritis.

1996 • 124 citations

Cytokine-mediated regulation of human leukocyte gelatinases and role in arthritis.

1991 • 107 citations

Morphologic demonstration of two stages in the development of type II collagen-induced arthritis.

1982 • 106 citations

Therapy against murine collagen‐induced arthritis with T cell receptor V_β‐specific antibodies

1991 • 102 citations

Genetic, hormonal and behavioural influence on spontaneously developing arthritis in normal mice

1992 • 87 citations

Anti‐T cell receptor antibody treatment of rats with established autologous collagen‐induced arthritis: suppression of arthritis without reduction of anti‐type II collagen autoantibody levels

1991 • 81 citations

Phagocytic lining cells determine local expression of inflammation in type II collagen–induced arthritis

1996 • 67 citations

Stimulation of human synovial fibroblast DNA synthesis by recombinant human cytokines.

1988 • 64 citations

Reduced susceptibility to collagen-induced arthritis in mice deficient in intercellular adhesion molecule-1.

1996 • 59 citations

Immunogenetics of Collagen-Induced Arthritis in Rats

1988 • 58 citations

Susceptibility of DA Rats to Arthritis Induced With Adjuvant Oil or Rat Collagen is Determined by Genes Both Within and Outside the Major Histocompatibility Complex

1996 • 56 citations

Immunogenetics of collagen-induced arthritis in rats. Both MHC and non-MHC gene products determine the epitope specificity of immune response to bovine and chick type II collagens.

1992 • 40 citations

Involvement of Macrophages and Denidritic Cells in Synovial Inflammation of Collagen Induced Arthritis in Dba/1 Mice and Spontaneous Arthritis in Mrl/Lpr Mice

1991 • 37 citations

Altered Th1/Th2 balance associated with non‐major histocompatibility complex genes in collagen‐induced arthritis in resistant and non‐resistant rat strains

1997 • 34 citations

Transfer of type II collagen‐induced arthritis from DBA/1 to severe combined immunodeficiency mice can be prevented by blockade of Mac‐1

1996 • 33 citations

Cartilage specific collagen activates macrophages and the alternative pathway of complement: evidence for an immunopathogenic concept of rheumatoid arthritis.

1982 • 33 citations

Stimulation of interleukin‐1α and interleukin‐1β release from human monocytes by cyanogen bromide peptides of type ii collagen

1988 • 25 citations

Resistance to Collagen-Induced Arthritis in DBA/1 Mice by Intraperitoneal Administration of Soluble Type II Collagen Involves Both CD4⁺and CD8⁺T Lymphocytes

1989 • 19 citations

Activation of Neutrophils by Factors Released from Alveolar Macrophages Stimulated with Collagen-like Polypeptides

1990 • 15 citations

Synovial Mesenchymal Reaction as a Perpetuating Principle

1995 • 3 citations

Interactions between H-2 and background genes modulate collagen induced arthritis in high (HI) and low (LI) antibody producer Biozzi mice

1997 • 2 citations