Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotransposon in woodchuck liver tumors

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

HEPATOCELLULAR CARCINOMA AND HEPATITIS B VIRUS

1981 • 2,891 citations

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

1982 • 1,790 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

The hepatitis B virus

1985 • 1,219 citations

Firefly Luciferase Gene: Structure and Expression in Mammalian Cells

1987 • 924 citations

Targeted integration of adeno-associated virus (AAV) into human chromosome 19.

1991 • 774 citations

Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma

1990 • 660 citations

A virus similar to human hepatitis B virus associated with hepatitis and hepatoma in woodchucks.

1978 • 657 citations

Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region

1984 • 642 citations

Hepatocellular carcinoma and the hepatitis B virus: evidence for a causal association.

1978 • 588 citations

Spi-1 is a putative oncogene in virally induced murine erythroleukaemias

1988 • 470 citations

Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma

1986 • 399 citations

Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas.

1992 • 311 citations

Rapid Cytoplasmic Turnover of c-myc mRNA: Requirement of the 3′ Untranslated Sequences

1987 • 302 citations

Nucleotide sequence of a cloned woodchuck hepatitis virus genome: comparison with the hepatitis B virus sequence

1982 • 296 citations

A human hepatitis B viral enhancer element.

1985 • 286 citations

The preS2/S region of integrated hepatitis B virus DNA encodes a transcriptional transactivator

1990 • 284 citations

Hepatocarcinogenicity of the woodchuck hepatitis virus.

1987 • 273 citations

Highly preferred targets for retrovirus integration

1988 • 262 citations

Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites

1987 • 248 citations

Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumours

1990 • 245 citations

myc Family Oncogenes in the Development of Normal and Neoplastic Cells

1991 • 245 citations

Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation.

1984 • 234 citations

Acceptor sites for retroviral integrations map near DNase I-hypersensitive sites in chromatin

1986 • 212 citations

Transcriptionally active genome regions are preferred targets for retrovirus integration

1990 • 210 citations

Activation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma

1988 • 192 citations

A transactivating function encoded in the hepatitis B virus X gene is conserved in the integrated state.

1988 • 174 citations

Integration of papillomavirus DNA near myc genes in genital carcinomas and its consequences for proto-oncogene expression

1991 • 168 citations

A Liver-Specific Enhancer in the Core Promoter Region of Human Hepatitis B Virus

1989 • 168 citations

Integration of hepatitis B virus DNA and its implications for hepatocarcinogenesis.

1990 • 162 citations

Transmission of the hepatitis B virus-associated delta agent to the eastern woodchuck.

1984 • 159 citations

Hepatocellular carcinoma in woodchuck hepatitis virus-infected woodchucks: Presence of viral DNA in tumor tissue from chronic carriers and animals serologically recovered from acute infections

1989 • 147 citations

Modulation of the liver specific phenotype in the human hepatoblastoma line Hep G2

1989 • 134 citations

Cloning and structural analysis of integrated woodchuck hepatitis virus sequences from hepatocellular carcinomas of woodchucks

1982 • 125 citations

N-myc is frequently activated by proviral insertion in MuLV-induced T cell lymphomas.

1989 • 109 citations

Regulation of hepatitis B virus gene expression by its two enhancers.

1992 • 96 citations

Retroviral Insertions 90 Kilobases Proximal to the Evi-1 Myeloid Transforming Gene Activate Transcription from the Normal Promoter

1991 • 86 citations

Natural history of woodchuck hepatitis virus infections during the course of experimental viral infection: molecular virologic features of the liver and lymphoid tissues

1989 • 83 citations

Proviral Rearrangements and Overexpression of a New Cellular Gene (nov) in Myeloblastosis-Associated Virus Type 1-Induced Nephroblastomas

1992 • 74 citations

Chromosomal sites for hepatitis B virus integration in human hepatocellular carcinoma

1991 • 71 citations

Frequent amplification of c-myc in ground squirrel liver tumors associated with past or ongoing infection with a hepadnavirus.

1992 • 69 citations

Hepatitis delta virus (HDV) and woodchuck hepatitis virus (WHV) nucleic acids in tissues of HDV-infected chronic WHV carrier woodchucks

1989 • 62 citations

Woodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host

1991 • 57 citations

A novel non-enzymatic procedure for removing DNA template from RNA transcription mixtures.

1991 • 54 citations

Targeted integration of baboon endogenous virus in the BEVI locus on human chromosome 6

1983 • 32 citations

Insertional activation of N-myc by endogenous Moloney-like murine retrovirus sequences in macrophage cell lines derived from myeloma cell line-macrophage hybrids.

1989 • 32 citations

Multiple rearrangements and activated expression of c-myc induced by woodchuck hepatitis virus integration in a primary liver tumour

1992 • 21 citations

Regulation of N-myc gene expression: use of an adenovirus vector to demonstrate posttranscriptional control.

1990 • 21 citations

N-myc activation by proviral insertion in MCF 247-induced murine T-cell lymphomas.

1989 • 18 citations

Nucleotide sequence analysis of three different hepatitis delta viruses isolated from a woodchuck and humans

1991 • 16 citations

A coordinated proto-oncogene expression characterizes MCF 247 murine leukemia virus-induced T-cell lymphomas irrespectively of proviral insertion affecting myc loci

1990 • 10 citations

Experimental hepatitis delta virus infection in the animal model.

1991 • 9 citations

Regulation of N-myc Gene Expression: Use of an Adenovirus Vector To Demonstrate Posttranscriptional Control

1990 • 5 citations