Integration of papillomavirus DNA near myc genes in genital carcinomas and its consequences for proto-oncogene expression

A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions.

1983 • 2,011 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.

1984 • 1,308 citations

Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes

1981 • 959 citations

Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma

1990 • 660 citations

Papillomaviruses in anogenital cancer as a model to understand the role of viruses in human cancers.

1989 • 522 citations

The Physical State of Human Papillomavirus Type 16 DNA in Benign and Malignant Genital Tumours

1985 • 480 citations

Molecular cloning and characterization of the human β-like globin gene cluster

1980 • 452 citations

Different human cervical carcinoma cell lines show similar transcription patterns of human papillomavirus type 18 early genes.

1986 • 440 citations

Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas.

1987 • 345 citations

A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma

1987 • 282 citations

High-resolution chromosomal localization of human genes for amylase, proopiomelanocortin, somatostatin, and a DNA fragment (D3S1) by in situ hybridization.

1983 • 274 citations

Human N-myc is closely related in organization and nucleotide sequence to c-myc

1986 • 273 citations

Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumours

1990 • 245 citations

Enzymatic cross-linking of involucrin and other proteins by keratinocyte particulates in vitro

1985 • 235 citations

Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation.

1984 • 234 citations

Transduction and rearrangement of the myc gene by feline leukaemia virus in naturally occurring T-cell leukaemias

1984 • 196 citations

Activation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma

1988 • 192 citations

Chromosomal integration sites of human papillomavirus DNA in three cervical cancer cell lines mapped by in situ hybridization

1987 • 184 citations

Integration of human papillomavirus type 16 DNA sequences: a possible early event in the progression of genital tumors

1987 • 163 citations

Integration sites of human papillomavirus 18 DNA sequences on HeLa cell chromosomes

1987 • 152 citations

C-myc PROTO-ONCOGENE EXPRESSION AND PROGNOSIS IN EARLY CARCINOMA OF THE UTERINE CERVIX

1987 • 150 citations

Mapping of single-copy DNA sequences on human chromosomes by in situ hybridization with biotinylated probes: enhancement of detection sensitivity by intensified-fluorescence digital-imaging microscopy.

1989 • 138 citations

High correlation between molecular alterations of the c-myc oncogene and carcinoma of the uterine cervix.

1987 • 127 citations

N-myc is frequently activated by proviral insertion in MuLV-induced T cell lymphomas.

1989 • 109 citations

The Human Gene Mapping Workshops in transition

1989 • 108 citations

Long-distance activation of the Myc protooncogene by provirus insertion in Mlvi-1 or Mlvi-4 in rat T-cell lymphomas.

1990 • 101 citations

Regional chromosome localization of human papillomavirus intergration sites near fragile sites, oncogenes, and cancer chromosome breakpoints

1988 • 98 citations

Viral integration, fragile sites, and proto-oncogenes in human neoplasia

1990 • 93 citations

Human papillomavirus type 18 DNA is integrated at a single chromosome site in cervical carcinoma cell line SW756

1987 • 75 citations

Increased level of amplification of the c-myc oncogene in tumors induced in nude mice by a human breast carcinoma cell line.

1985 • 66 citations

Amplification of the integrated viral transforming genes of human papillomavirus 18 and its 5'-flanking cellular sequence located near the myc protooncogene in HeLa cells.

1989 • 57 citations

Chromosomal insertion of human papillomavirus 18 sequences in HeLa cells detected by nonisotopic in situ hybridization and reflection contrast microscopy

1987 • 36 citations

Human papillomavirus type 16 DNA is integrated into chromosome region 12q14-q15 in a cell line derived from a vulvar intraepithelial neoplasia

1990 • 25 citations