DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

1990 • 3,134 citations

The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR).

1994 • 1,140 citations

Role of Steroidogenic Acute Regulatory Protein in Adrenal and Gonadal Steroidogenesis

1995 • 1,019 citations

Regulation of the Acute Production of Steroids in Steroidogenic Cells*

1996 • 995 citations

An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

1994 • 857 citations

Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism

1994 • 764 citations

CREM gene: Use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription

1991 • 655 citations

Specific Recognition of Cruciform DNA by Nuclear Protein HMG1

1989 • 596 citations

A Dosage Sensitive Locus at Chromosome Xp21 Is Involved in Male to Female Sex Reversal

1995 • 541 citations

DAX-1 Inhibits SF-1-Mediated Transactivation via a Carboxy-Terminal Domain That Is Deleted in Adrenal Hypoplasia Congenita

1997 • 469 citations

Electron diffraction analysis of structural changes in the photocycle of bacteriorhodopsin.

1993 • 448 citations

Mouse Dax1 expression is consistent with a role in sex determination as well as in adrenal and hypothalamus function

1996 • 404 citations

Structure of the HMG box motif in the B-domain of HMG1.

1993 • 403 citations

Ancestry and diversity of the HMG box superfamily

1993 • 328 citations

Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development.

1996 • 303 citations

Intercalation, DNA Kinking, and the Control of Transcription

1996 • 279 citations

Steroidogenic Factor 1-Dependent Promoter Activity of the Human Steroidogenic Acute Regulatory Protein (StAR) Gene

1996 • 266 citations

Local Supercoil-Stabilized DNA Structure

1991 • 251 citations

Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit.

1987 • 248 citations

Characterization of the Promoter Region of the Mouse Gene Encoding the Steroidogenic Acute Regulatory Protein

1997 • 235 citations

The functional versatility of CREM is determined by its modular structure.

1993 • 226 citations

Structure of the human steroidogenic acute regulatory (StAR) protein gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase

1995 • 211 citations

A Transcriptional Silencing Domain in DAX-1 Whose Mutation Causes Adrenal Hypoplasia Congenita

1997 • 186 citations

Hormonal and developmental regulation of DAX-1 expression in Sertoli cells.

1996 • 128 citations

[52] Adrenocortical Y1 cells

1979 • 115 citations

Institute to boost Japan sequencing efforts

1994 • 3 citations

Deleted Work

1955 • 0 citations