The fate of plasmid DNA after intravenous injection in mice: involvement of scavenger receptors in its hepatic uptake.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Handbook of Physiology.

1960 • 10,428 citations

A pharmacokinetic analysis program (multi) for microcomputer.

1981 • 2,465 citations

The Basic Science of Gene Therapy

1993 • 1,767 citations

Poly(ethylene glycol) chemistry : biotechnical and biomedical applications

1992 • 1,437 citations

Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

1990 • 1,039 citations

Cationic liposome-mediated transfection

1989 • 974 citations

In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

1992 • 953 citations

Systemic Gene Expression After Intravenous DNA Delivery into Adult Mice

1993 • 725 citations

Receptor-mediated gene delivery and expression in vivo.

1988 • 642 citations

Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II

1990 • 460 citations

Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.

1991 • 431 citations

Gene transfer in vivo: sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake.

1994 • 306 citations

Targeting Genes: Delivery and Persistent Expression of a Foreign Gene Driven by Mammalian Regulatory Elements in Vivo

1989 • 292 citations

Molecular flypaper, host defense, and atherosclerosis. Structure, binding properties, and functions of macrophage scavenger receptors.

1993 • 271 citations

Disposition characteristics of macromolecules in tumor-bearing mice.

1990 • 220 citations

Polynucleotide binding to macrophage scavenger receptors depends on the formation of base-quartet-stabilized four-stranded helices.

1993 • 216 citations

The collagenous domains of macrophage scavenger receptors and complement component C1q mediate their similar, but not identical, binding specificities for polyanionic ligands.

1993 • 150 citations

Liposomes as agents of DNA transfer

1993 • 133 citations

Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and polysaccharide derivatives.

1992 • 116 citations

Fate of Injected Deoxyribonucleic Acid in Mice

1963 • 101 citations

Retrovirus-mediated gene transfer to purified hemopoietic stem cells with long-term lympho-myelopoietic repopulating ability.

1989 • 98 citations

Effect of DNA size and strandedness on the in vivo clearance and organ localization of DNA.

1984 • 98 citations

Kinetics and mechanisms for removal of circulating single-stranded DNA in mice.

1978 • 93 citations

Therapeutic effects of superoxide dismutase derivatives modified with mono- or polysaccharides on hepatic injury induced by ischemia/reperfusion

1992 • 83 citations

Pharmacokinetics of receptor-mediated hepatic uptake of glycosylated albumin in mice

1992 • 72 citations

Rat liver Kupffer and endothelial cells express different binding proteins for modified low density lipoproteins. Kupffer cells express a 95-kDa membrane protein as a specific binding site for oxidized low density lipoproteins.

1994 • 70 citations

Pharmacokinetics of succinylated proteins and dextran sulfate in mice: Implications for hepatic targeting of protein drugs by direct succinylation via scavenger receptors

1994 • 66 citations

Interaction of Clq with DNA

1982 • 58 citations

Hepatic binding of DNA is mediated by a receptor on nonparenchymal cells.

1988 • 53 citations

Targeted delivery of superoxide dismutase to macrophages via mannose receptor-mediated mechanism

1994 • 45 citations

The Accumulation Mechanism of Cationic Mitomycin C-dextran Conjugates in the Liver: In-vivo Cellular Localization and In-vitro Interaction with Hepatocytes

1988 • 41 citations

Initial degradation of deoxyribonucleic acid after injection in mammals.

1965 • 37 citations

Clearance of human antibody/DNA immune complexes and free DNA from the circulation of the nonhuman primate

1987 • 37 citations

Disposition characteristics of macromolecules in the perfused tissue-isolated tumor preparation.

1992 • 36 citations