The Accumulation Mechanism of Cationic Mitomycin C-dextran Conjugates in the Liver: In-vivo Cellular Localization and In-vitro Interaction with Hepatocytes

Chapter 4 Preparation of Isolated Rat Liver Cells

1976 • 5,335 citations

A pharmacokinetic analysis program (multi) for microcomputer.

1981 • 2,465 citations

Mitomycin C: Current status and new developments

1979 • 296 citations

Microspheres and drug therapy: Pharmaceutical, immunological and medical aspects

1985 • 204 citations

Clearance Capacity of Rat Liver Kupffer, Endothelial, and Parenchymal Cells

1981 • 188 citations

The involvement of parenchymal, Kupffer and endothelial liver cells in the hepatic uptake of intravenously injected liposomes effects of lanthanum and gadolinium salts

1981 • 149 citations

Optimization of Drug Delivery

1985 • 144 citations

Interactions of liposomes with the reticuloendothelial system effects of reticuloendothelial blockade on the clearance of large unilamellar vesicles

1981 • 140 citations

In Vivo Uptake of Polyisobutyl Cyanoacrylate Nanoparticles by Rat Liver Kupffer, Endothelial, andParenchymal Cells

1984 • 112 citations

Mitomycin C-dextran conjugate: a novel high molecular weight pro-drug of mitomycin C

1980 • 103 citations

Enhanced lymphatic delivery of mitomycin C conjugated with dextran.

1984 • 92 citations

Characterization of a membrane-associated receptor from rat sinusoidal liver cells that binds formaldehyde-treated serum albumin.

1985 • 90 citations

Fluid endocytosis by rat liver and spleen. Experiments with 125I-labelled poly(vinylpyrrolidone) in vivo

1980 • 68 citations

Disposition and pharmacokinetics of a polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate, in the rat.

1984 • 66 citations

Regeneration characteristics of mitomycin C-dextran conjugate in relation to its activity.

1983 • 50 citations

Physico-chemical and antitumor characteristics of high molecular weight prodrugs of Mitomycin C.

1982 • 45 citations

Cellular interaction and in vitro antitumor activity of mitomycin C-dextran conjugate.

1986 • 44 citations

Physicochemical and antitumor characteristics of some polyamino acid prodrugs of mitomycin C

1984 • 43 citations

Cyanogen bromide activation of polysaccharides

1977 • 38 citations

Uptake and degradation of bovine testes β-galactosidase by parenchymal and nonparenchymal rat liver cells

1985 • 31 citations

Absorption characteristics of macromolecular prodrugs of mitomycin C following intramuscular administration.

1986 • 17 citations

Plasma disposition and in vivo and in vitro antiumor activities of mitomycin C-dextran conjugate in relation to the mode of action.

1985 • 17 citations

Cancer Drug Delivery Systems: Macromolecular Prodrugs of Mitomycin C

1984 • 1 citations