Disposition characteristics of macromolecules in tumor-bearing mice.

Chromatography of Proteins. I. Cellulose Ion-exchange Adsorbents

1956 • 1,295 citations

Transport of molecules across tumor vasculature

1987 • 856 citations

A simplified method of sample preparation for determination of tritium, carbon-14, or sulfur-35 in blood or tissue by liquid scintillation counting

1966 • 530 citations

Animal scale-up

1973 • 389 citations

The preparation and labeling of DTPA-coupled albumin

1982 • 329 citations

Absorptive-mediated endocytosis of cationized albumin and a beta-endorphin-cationized albumin chimeric peptide by isolated brain capillaries. Model system of blood-brain barrier transport.

1987 • 314 citations

Glomerular permselectivity: barrier function based on discrimination of molecular size and charge

1978 • 216 citations

Blood-brain barrier transport of cationized immunoglobulin G: enhanced delivery compared to native protein.

1989 • 211 citations

Disposition and tumor localization of mitomycin C-dextran conjugates in mice.

1987 • 176 citations

Renal tubular uptake of protein: effect of molecular charge

1983 • 118 citations

Preliminary Model for Methotrexate Pharmacokinetics

1970 • 111 citations

Pharmacokinetics of the monoclonal antibody B72.3 and its fragments labeled with either 125I or 111In.

1987 • 104 citations

Mitomycin C-dextran conjugate: a novel high molecular weight pro-drug of mitomycin C

1980 • 103 citations

Macromolecule-drug conjugates in targeted cancer chemotherapy.

1984 • 100 citations

Accessibility of circulating immunoglobulin G to the extravascular compartment of solid rat tumors.

1984 • 98 citations

Enhanced lymphatic delivery of mitomycin C conjugated with dextran.

1984 • 92 citations

A histochemical study of the distribution and fate of dextran in tissues of the mouse.

1953 • 78 citations

Chimeric peptides as a vehicle for peptide pharmaceutical delivery through the blood-brain barrier

1987 • 76 citations

Quantitative study of vascularity in Walker carcinoma 256.

1971 • 76 citations

Fluid endocytosis by rat liver and spleen. Experiments with 125I-labelled poly(vinylpyrrolidone) in vivo

1980 • 68 citations

Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration

1987 • 68 citations

Disposition and pharmacokinetics of a polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate, in the rat.

1984 • 66 citations

Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. I. Physicochemical characteristics and in vivo and in vitro antitumor activities

1987 • 60 citations

Regeneration characteristics of mitomycin C-dextran conjugate in relation to its activity.

1983 • 50 citations

Cellular interaction and in vitro antitumor activity of mitomycin C-dextran conjugate.

1986 • 44 citations

The Accumulation Mechanism of Cationic Mitomycin C-dextran Conjugates in the Liver: In-vivo Cellular Localization and In-vitro Interaction with Hepatocytes

1988 • 41 citations

Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran I: Synthesis and Characterization

1989 • 39 citations

Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran II: Biopharmaceutical and Pharmacological Properties

1989 • 37 citations

Covalent linkage of carboxypeptidase G2 to soluble dextrans—II

1987 • 36 citations

Antitumor activity of mitomycin C-dextran conjugate against various murine tumors.

1981 • 36 citations

Disposition characteristics of mitomycin C-dextran conjugate in normal and tumor-bearing muscles of rabbits.

1987 • 32 citations

A basic derivative of dextran and its interaction with serum albumin

1960 • 25 citations

Disposition of a Polymeric Prodrug of Mitomycin C, Mitomycin C-Dextran Conjugate, in the Perfused Rat Liver

1989 • 22 citations

Absorption characteristics of macromolecular prodrugs of mitomycin C following intramuscular administration.

1986 • 17 citations