The collagenous domains of macrophage scavenger receptors and complement component C1q mediate their similar, but not identical, binding specificities for polyanionic ligands.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Beyond Cholesterol

1989 • 6,533 citations

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

Book ReviewAmbulatory Pediatric Care

1989 • 2,075 citations

[19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1983 • 1,639 citations

Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

1990 • 1,039 citations

Role of oxidatively modified LDL in atherosclerosis

1990 • 614 citations

Recognition and plasma clearance of endotoxin by scavenger receptors

1991 • 529 citations

Regulation of the activity of the low density lipoprotein receptor in human fibroblasts

1975 • 477 citations

Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II

1990 • 460 citations

Mannose-binding proteins isolated from rat liver contain carbohydrate-recognition domains linked to collagenous tails. Complete primary structures and homology with pulmonary surfactant apoprotein.

1986 • 433 citations

Modification of human serum low density lipoprotein by oxidation — Characterization and pathophysiological implications

1987 • 400 citations

In vivo and in vitro uptake and degradation of acetylated low density lipoprotein by rat liver endothelial, Kupffer, and parenchymal cells.

1983 • 396 citations

Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions.

1990 • 360 citations

An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors.

1990 • 311 citations

Occurrence of small colloids in sea water

1991 • 289 citations

A human mannose-binding protein is an acute-phase reactant that shares sequence homology with other vertebrate lectins.

1988 • 274 citations

Molecular flypaper, host defense, and atherosclerosis. Structure, binding properties, and functions of macrophage scavenger receptors.

1993 • 271 citations

Purification and characterization of a bovine acetyl low density lipoprotein receptor.

1988 • 259 citations

Macromolecular organization of natural and recombinant lung surfactant protein SP 28–36

1988 • 253 citations

Scavenger receptor-mediated uptake and metabolism of lipid vesicles containing acidic phospholipids by mouse peritoneal macrophages.

1990 • 231 citations

Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells.

1985 • 219 citations

Polynucleotide binding to macrophage scavenger receptors depends on the formation of base-quartet-stabilized four-stranded helices.

1993 • 216 citations

Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein.

1991 • 214 citations

Structures and functions associated with the group of mammalian lectins containing collagen‐like sequences

1989 • 197 citations

Proteins involved in the activation and control of the two pathways of human complement

1983 • 169 citations

Molecular flypaper and atherosclerosis: structure of the macrophage scavenger receptor

1992 • 149 citations

Phospholipid binding and biophysical activity of pulmonary surfactant-associated protein (SAP)-35 and its non-collagenous COOH-terminal domains.

1986 • 125 citations

Rabbit aortic smooth muscle cells express inducible macrophage scavenger receptor messenger RNA that is absent from endothelial cells.

1992 • 125 citations

Mode of interaction of different polyanions with the first () the second (C2) and the fourth (C4) component of complement—I

1976 • 117 citations

Binding and complement activation by C-reactive protein via the collagen-like region of C1q and inhibition of these reactions by monoclonal antibodies to C-reactive protein and C1q.

1991 • 112 citations

Localization of sites through which C-reactive protein binds and activates complement to residues 14-26 and 76-92 of the human C1q A chain.

1992 • 106 citations

Phagocytic cell molecules that bind the collagen-like region of C1q. Involvement in the C1q-mediated enhancement of phagocytosis.

1991 • 101 citations

Complementation of mutations in the LDL pathway of receptor-mediated endocytosis by cocultivation of LDL receptor-defective hamster cell mutants

1983 • 93 citations

Secreted extracellular domains of macrophage scavenger receptors form elongated trimers which specifically bind crocidolite asbestos.

1993 • 83 citations

The reaction between the complement subcomponent C1q, IgG complexes and polyionic molecules.

1978 • 73 citations

Biosynthesis of the Collagen-like C1q Molecule and its Receptor Functions for Fc and Polyanionic Molecules on Macrophages

1983 • 67 citations

The type I and type II bovine scavenger receptors expressed in Chinese hamster ovary cells are trimeric proteins with collagenous triple helical domains comprising noncovalently associated monomers and Cys83-disulfide-linked dimers.

1991 • 63 citations

Unusual forms of low density lipoprotein receptors in hamster cell mutants with defects in the receptor structural gene.

1986 • 58 citations

The C1q subunit of the first component of complement binds to laminin: a mechanism for the deposition and retention of immune complexes in basement membrane.

1985 • 55 citations

Interaction of collagen with the lipids of tendon xanthomata.

1978 • 39 citations

Gram-negative Endotoxin: A Biologically Active Lipid

1988 • 33 citations

C1q component of complement binds to fibrinogen and fibrin

1988 • 28 citations

Mouse macrophage receptor for acetylated low density lipoprotein: demonstration of a fully functional subunit in the membrane and with purified receptor.

1992 • 15 citations

The binding of native DNA to the collagen-like segment of Clq.

1988 • 11 citations