Activation of Na+/H+ exchange and the expression of cellular proto-oncogenes in mitogen- and phorbol ester-treated lymphocytes.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Mapping Patterns of c- fos Expression in the Central Nervous System After Seizure

1987 • 1,771 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

Mechanisms of regulation of the Na+/H+ exchanger

1986 • 685 citations

Kinetic Properties of the Plasma Membrane Na+ -H+ Exchanger

1985 • 670 citations

A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH.

1984 • 544 citations

Effects of Growth Factors on Intracellular pH Regulation

1986 • 498 citations

Cytoplasmic pH regulation in thymic lymphocytes by an amiloride-sensitive Na+/H+ antiport.

1984 • 434 citations

Blockade of the Na+/H+ antiport abolishes growth factor-induced DNA synthesis in fibroblasts. Structure-activity relationships in the amiloride series.

1984 • 305 citations

Structure of the FBJ murine osteosarcoma virus genome: molecular cloning of its associated helper virus and the cellular homolog of the v-fos gene from mouse and human cells.

1983 • 282 citations

Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport.

1985 • 254 citations

Cytoplasmic pH, a key determinant of growth factor‐induced DNA synthesis in quiescent fibroblasts

1985 • 247 citations

Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.

1985 • 203 citations

Activation of a heterologous promoter in response to dexamethasone and cadmium by metallothionein gene 5′-flanking DNA

1984 • 195 citations

Amiloride Directly Inhibits the Na,K-ATPase Activity of Rabbit Kidney Proximal Tubules

1983 • 172 citations

Amiloride directly inhibits growth factor receptor tyrosine kinase activity.

1985 • 155 citations

Transmembrane Ion Fluxes during Activation of Human T Lymphocytes: Role of Ca²⁺, Na⁺/H⁺ Exchange and Phospholipid Turnover

1987 • 154 citations

Requirements for the simultaneous presence of phorbol esters and calcium ionophores in the expression of human T lymphocyte proliferation-related genes.

1987 • 122 citations

Cytoplasmic [Ca2+] and intracellular pH in lymphocytes. Role of membrane potential and volume-activated Na+/H+ exchange.

1987 • 98 citations

The fos Gene as "Master Switch"

1987 • 94 citations

IONIC TRIGGERS IN THE FERTILIZATION OF SEA URCHIN EGGS

1980 • 82 citations

Amiloride blocks cell-free protein synthesis at levels attained inside cultured rat hepatocytes

1982 • 77 citations

Mitogenic effect of alkaline pH on quiescent, serum-starved cells.

1981 • 64 citations

Volume regulation by human lymphocytes. Identification of differences between the two major lymphocyte subpopulations.

1982 • 57 citations

Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport

1987 • 50 citations

Amiloride intercalates into DNA and inhibits DNA topoisomerase II.

1987 • 45 citations

Sodium ion influx in proliferating lymphocytes: An early component of the mitogenic signal

1987 • 42 citations

Activation of the Na+/H+ antiport is not required for lectin-induced proliferation of human T lymphocytes.

1986 • 41 citations

A sodium requirement for mitogen-induced proliferation in human peripheral blood lymphocytes

1981 • 37 citations

Avian retrovirus S13: Properties of the genome and of the transformation-specific protein

1985 • 28 citations

Amiloride inhibition of DNA synthesis and immunoglobulin production by activated human peripheral blood mononuclear cells is independent of sodium/hydrogen antiport.

1986 • 22 citations

The Na⁺‐H⁺ Antiport Is a Mediator of Cell Proliferation

1987 • 12 citations

Inhibition of T‐lymphocyte activation by amiloride

1987 • 10 citations