RB and Cdc2 expression in brain: correlations with 3H-thymidine incorporation and neurogenesis

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Temporal profile of neuronal damage in a model of transient forebrain ischemia

1982 • 2,695 citations

Effects of an Rb mutation in the mouse

1992 • 1,779 citations

The E2F transcription factor is a cellular target for the RB protein

1991 • 1,461 citations

Neurogenesis in the Adult Rat: Electron Microscopic Analysis of Light Radioautographs

1977 • 1,438 citations

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1992 • 1,285 citations

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1989 • 1,031 citations

Requirement for a functional Rb-1 gene in murine development

1992 • 1,015 citations

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

1989 • 990 citations

The density and distribution of ischemic brain injury in the rat following 2?10 min of forebrain ischemia

1984 • 968 citations

Abnormalities in Structure and Expression of the Human Retinoblastoma Gene in SCLC

1988 • 905 citations

Migration and distribution of two populations of hippocampal granule cell precursors during the perinatal and postnatal periods

1990 • 805 citations

Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement

1988 • 786 citations

Adrenal hormones suppress cell division in the adult rat dentate gyrus

1992 • 638 citations

Inactivation of the Retinoblastoma Susceptibility Gene in Human Breast Cancers

1988 • 608 citations

Suppression of Tumorigenicity of Human Prostate Carcinoma Cells by Replacing a Mutated RB Gene

1990 • 606 citations

Neurons in the Rat Dentate Gyrus Granular Layer Substantially Increase During Juvenile and Adult Life

1982 • 589 citations

Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells.

1990 • 543 citations

Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

1991 • 541 citations

Cell Cycle-Dependent Regulation of Phosphorylation of the Human Retinoblastoma Gene Product

1989 • 457 citations

Second Nonocular Tumors in Retinoblastoma Survivors

1984 • 442 citations

The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells

1989 • 439 citations

Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections

1988 • 429 citations

Structural Rearrangement of the Retinoblastoma Gene in Human Breast Carcinoma

1988 • 423 citations

The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T

1990 • 402 citations

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

1990 • 364 citations

The retinoblastoma protein is phosphorylated on multiple sites by human cdc2.

1991 • 343 citations

Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase.

1991 • 304 citations

Changes in the total number of dentate granule cells in juvenile and adult rats: A correlated volumetric and 3H-thymidine autoradiographic study

1982 • 275 citations

Oncogenes in development

1987 • 250 citations

Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein.

1989 • 248 citations

Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleotides.

1991 • 243 citations

Association of cdk2 Kinase with the Transcription Factor E2F During S Phase

1992 • 239 citations

Golgi studies on the development of granule cells of the rat olfactory bulb with reference to migration in the subependymal layer

1987 • 182 citations

Cell cycle control genes in fission yeast and mammalian cells

1988 • 168 citations

Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer

1991 • 158 citations

Unraveling of mitotic control mechanisms

1988 • 150 citations

The postnatal development of the main olfactory bulb of the rat.

1979 • 108 citations

Subgranular Zone of the Dentate Gyrus of Young Rabbits As a Secondary Matrix

1982 • 104 citations

Antibodies detecting abnormalities of the retinoblastoma susceptibility gene product (pp110RB) in osteosarcomas and synovial sarcomas.

1989 • 88 citations

Requirement for p34cdc2 kinase is restricted to mitosis in the mammalian cdc2 mutant FT210

1992 • 65 citations

The Retinoblastoma Gene Product Regulates Sp1-Mediated Transcription

1992 • 55 citations

DNA-binding activity of retinoblastoma protein is intrinsic to its carboxyl-terminal region.

1990 • 37 citations

Expression of proto-oncogenes in neural tissues

1988 • 34 citations

Regulated expression of the RB “tumor suppressor gene” in normal lymphocyte mitogenesis: Elevated expression in transformed leukocytes and role as a “status quo” gene

1991 • 16 citations