Organization of the transcriptional control region of the E1b gene of adenovirus type 5

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

PROTEIN-DNA RECOGNITION

1984 • 1,649 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

Promoter-specific activation of RNA polymerase II transcription by Sp1

1986 • 1,054 citations

[17] A rapid alkaline extraction method for the isolation of plasmid DNA

1983 • 983 citations

Enhanced autoradiographic detection of ³²P and ¹²⁵I using intensifying screens and hypersensitized film

1977 • 947 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

Transcriptional selectivity of viral genes in mammalian cells

1986 • 722 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

Structure of the adenovirus 2 early mRNAs

1978 • 591 citations

Enhancer elements

1983 • 576 citations

A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity

1984 • 537 citations

Multiple sequence motifs are involved in SV40 enhancer function.

1986 • 511 citations

Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast

1987 • 476 citations

Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.

1980 • 471 citations

The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element

1983 • 467 citations

ADENOVIRUS PROMOTERS AND E1A TRANSACTIVATION

1986 • 460 citations

Regulation of the human interleukin-2 receptor α chain promoter: Activation of a nonfunctional promoter by the transactivator gene of HTLV-I

1987 • 423 citations

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

1987 • 394 citations

POSITIVE CONTROL OF TRANSCRIPTION INITIATION IN BACTERIA

1984 • 369 citations

Factors involved in specific transcription in mammalian RNA polymerase II. Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site.

1987 • 355 citations

Common Control of the Heat Shock Gene and Early Adenovirus Genes: Evidence for a Cellular E1A-like Activity

1984 • 331 citations

[35] In Vitro transcription: Whole-cell extract

1983 • 311 citations

The SV40 enhancer is composed of multiple functional elements that can compensate for one another

1986 • 293 citations

The 2.2 kb E1b mRNA of human Ad12 and Ad5 codes for two tumor antigens starting at different AUG triplets

1981 • 290 citations

Promoters and heterogeneous 5′ termini of the messenger RNAs of adenovirus serotype 2

1981 • 289 citations

Extracellular nucleases of Pseudomonas BAL 31. III. Use of the double-strand deoxyriboexonuclease activity as the basis of a convenient method for the mapping of fragments of DNA produced by cleavage with restriction enzymes

1978 • 234 citations

A TATA box implicated in E1A transcriptional activation of a simple adenovirus 2 promoter

1987 • 227 citations

E1a regions of the human adenoviruses and of the highly oncogenic simian adenovirus 7 are closely related

1985 • 213 citations

The ribonuclease activity of crystallized pancreatic deoxyribonuclease

1966 • 211 citations

A cellular transcription factor E4F1 interacts with an E1a-inducible enhancer and mediates constitutive enhancer function in vitro.

1987 • 208 citations

Polyomavirus enhancer contains multiple redundant sequence elements that activate both DNA replication and gene expression.

1985 • 206 citations

Regulation of the appearance of cytoplasmic RNAs from region 1 of the adenovirus 2 genome

1978 • 184 citations

Regulation of the Primary Expression of the Early Adenovirus Transcription Units

1979 • 184 citations

Cis-acting induction of adenovirus transcription

1983 • 180 citations

A Genetic Approach to Promoter Recognition During trans Induction of Viral Gene Expression

1986 • 163 citations

Identification of a promoter component involved in positioning the 5' termini of simian virus 40 early mRNAs.

1981 • 162 citations

Functional Analysis of Adenovirus-5 Host-range Deletion Mutants Defective for Transformation of Rat Embryo Cells

1980 • 162 citations

Mammalian Deoxyribonucleic Acid-dependent Ribonucleic Acid Polymerases

1973 • 158 citations

Cloning of a DNA fragment from the left-hand terminus of the adenovirus type 2 genome and its use in site-directed mutagenesis

1981 • 157 citations

Specific protein binding to the simian virus 40 enhancer in vitro.

1986 • 135 citations

Proteins and messenger RNAs of the transforming region of wild-type and mutant adenoviruses

1980 • 132 citations

Physical mapping of a large-plaque mutation of adenovirus type 2

1979 • 125 citations

In vitro translation products specified by the transforming region of adenovirus type 2

1979 • 117 citations

Comparison of nucleotide sequences of the early E1a regions for subgroups A, B and C of human adenoviruses

1980 • 107 citations

The use of exonuclease III for preparing single stranded DNA for use as a template in the chain terminator sequencing method

1979 • 101 citations

Mapping of RNA initiation sites by high doses of uv irradiation: Evidence for three independent promoters within the left 11% of the Ad-2 genome

1979 • 100 citations

Downstream sequences affect transcription initiation from the adenovirus major late promoter.

1986 • 97 citations

Stimulation of in vitro transcription from heterologous promoters by the simian virus 40 enhancer.

1984 • 95 citations

Transformation by and Oncogenicity of Human Adenoviruses

1984 • 94 citations

The E4 transcilpilonal unit of Ad2: far upstream sequences are required for its transactivation by E1A

1984 • 86 citations

A transcription enhancer acts in vitro over distances of hundreds of base-pairs on both circular and linear templates but not on chromatin-reconstituted DNA

1984 • 86 citations

Adenovirus 5 E2 transcription unit: an E1A-inducible promoter with an essential element that functions independently of position or orientation.

1984 • 86 citations

Transcriptional analysis of the adenovirus-5 EIII promoter: absence of sequence specificity for stimulation by EIa gene products

1985 • 70 citations

Control of adenovirus late promoter expression in two human cell lines.

1985 • 69 citations

Specific Protein Binding to the Simian Virus 40 Enhancer in Vitro

1986 • 68 citations

Accumulation of early and intermediate mRNA species during subgroup C adenovirus productive infections

1984 • 67 citations

The E1b promoter of Ad12 in mouse L tk- cells is activated by adenovirus region E1a.

1983 • 60 citations

Organization of early region 1B of human adenovirus type 2: identification of four differentially spliced mRNAs

1985 • 56 citations

Molecular cloning of the murine adenosine deaminase gene from a genetically enriched source: identification and characterization of the promoter region.

1986 • 55 citations

The Structure of the Genome

1984 • 52 citations

Regulation of adenovirus gene expression in human WI38 cells by an E1B-encoded tumor antigen.

1986 • 50 citations

Proximal and distal domains that control in vitro transcription of the adenovirus IVa2 gene.

1984 • 50 citations

Downstream Sequences Affect Transcription Initiation from the Adenovirus Major Late Promoter

1986 • 48 citations

DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2.

1982 • 46 citations

The structure and functions of the adenovirus early region 1 proteins

1987 • 44 citations

Far upstream sequences are required for efficient transcription from the adenovirus-2 E1A transcription unit

1983 • 42 citations

The E4 promoter of adenovirus type 2 contains an E1A dependent cis-actlng element

1986 • 42 citations

Adenovirus 5 E2 Transcription Unit: an E1A-Inducible Promoter with an Essential Element That Functions Independently of Position or Orientation

1984 • 40 citations

Functional analysis of the nucleotide sequence surrounding the cap site for adenovirus type 5 region E1A messenger RNAs

1983 • 39 citations

Genetic analysis of the human thymidine kinase gene promoter.

1986 • 38 citations

Control of Adenovirus Late Promoter Expression in Two Human Cell Lines

1985 • 36 citations

Expression of adenoviral genetic information in productively infected cells

1982 • 36 citations

Sequence analysis in the E1 region of adenovirus type 4 DNA

1986 • 32 citations

The sequence motifs that are involved in SV40 enhancer function also control SV40 late promoter activity

1987 • 32 citations

The role of tyrosyl-hydrogen bonds in the quaternary structure of the glutamate dehydrogenase molecule

1962 • 31 citations

Control of Cellular and Viral Transcription During Adenovirus Infectio

1986 • 27 citations

Selective inhibition of adenovirus type 2 early region II and III transcription by an anisomycin block of protein synthesis.

1982 • 24 citations

Requirement for distal upstream sequences for maximal transcription in vitro of early region IV of adenovirus.

1984 • 23 citations

Genetic Analysis of the Human Thymidine Kinase Gene Promoter

1986 • 22 citations

Molecular Cloning of the Murine Adenosine Deaminase Gene from a Genetically Enriched Source: Identification and Characterization of the Promoter Region

1986 • 19 citations

Regulation of Adenovirus Gene Expression in Human WI38 Cells by an E1B-Encoded Tumor Antigen

1986 • 19 citations

Adenovirus-2 E1a and E1b gene products regulate enhancer mediated transcription

1986 • 19 citations

Selective Inhibition of Adenovirus Type 2 Early Region II and III Transcription by an Anisomycin Block of Protein Synthesis

1982 • 11 citations

Transcription of adenovirus 5 early region 1b is elevated in permissive cells infected by a mutant with an upstream deletion

1982 • 11 citations

Requirement for Distal Upstream Sequences for Maximal Transcription In Vitro of Early Region IV of Adenovirus

1984 • 10 citations