Purification and properties of phosphatidic acid phosphatase from porcine thymus membranes.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1984 • 3,959 citations

Assay of proteins in the presence of interfering materials

1976 • 3,217 citations

Signaling through phosphatidylcholine breakdown.

1990 • 1,362 citations

Characterization of membrane proteins in detergent solutions

1976 • 853 citations

Phosphatidylcholine Hydrolysis by Phospholipase D Determines Phosphatidate and Diglyceride Levels in Chemotactic Peptide-stimulated Human Neutrophils

1989 • 429 citations

Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase.

1992 • 368 citations

The Effect of GTPase Activating Protein Upon Ras Is Inhibited by Mitogenically Responsive Lipids

1989 • 287 citations

Kinetic analysis of phospholipase A2 activity toward mixed micelles and its implications for the study of lipolytic enzymes

1975 • 278 citations

Plasma membrane fractions from rat liver contain a phosphatidate phosphohydrolase distinct from that in the endoplasmic reticulum and cytosol.

1991 • 271 citations

Porcine diacylglycerol kinase sequence has zinc finger and E–F hand motifs

1990 • 218 citations

Diacylglycerol kinase: a key modulator of signal transduction?

1990 • 189 citations

sn-1,2-Diacylglycerol kinase of Escherichia coli. Mixed micellar analysis of the phospholipid cofactor requirement and divalent cation dependence.

1986 • 148 citations

The purification and characterization of CTP:phosphorylcholine cytidylyltransferase from rat liver.

1986 • 143 citations

Diacylglycerol kinase from pig brain. Purification and phospholipid dependencies.

1983 • 135 citations

Rapid protein phosphorylation induced by phorbol ester in HL-60 cells. Unique alkali-stable phosphorylation of a 17,000-dalton protein detected by two-dimensional gel electrophoresis.

1983 • 133 citations

Porcine 80-kDa diacylglycerol kinase is a calcium-binding and calcium/phospholipid-dependent enzyme and undergoes calcium-dependent translocation.

1991 • 131 citations

Different effects of sphingosine, R59022 and anionic amphiphiles on two diacylglycerol kinase isozymes purified from porcine thymus cytosol

1989 • 123 citations

Purification and Characterization of Phosphatidate Phosphatase from Saccharomyces cerevisiae

1989 • 104 citations

Complement C5a activation of phospholipase D in human neutrophils. A major route to the production of phosphatidates and diglycerides.

1990 • 101 citations

Sphingosine inhibits phosphatidate phosphohydrolase in human neutrophils by a protein kinase C-independent mechanism

1991 • 97 citations

Inhibition of phosphatidic acid phosphohydrolase activity by sphingosine

1990 • 87 citations

Regulation of phosphatidate phosphatase activity by inositol in Saccharomyces cerevisiae

1988 • 86 citations

Interleukin-1 rapidly stimulates lysophosphatidate acyltransferase and phosphatidate phosphohydrolase activities in human mesangial cells.

1991 • 85 citations

Regulatory role of phosphatidate phosphatase in triacylglycerol synthesis of Saccharomyces cerevisiae

1984 • 66 citations

Partial Purification, Properties, and Subcellular Distribution of Rat Liver Phosphatidate Phosphatase 1

1975 • 65 citations

Phosphatidate phosphatase from Saccharomyces cerevisiae. Isolation of 45- and 104-kDa forms of the enzyme that are differentially regulated by inositol

1991 • 64 citations

Kinetic analysis of yeast phosphatidate phosphatase toward Triton X-100/phosphatidate mixed micelles.

1990 • 59 citations

A rapid assay for measuring the activity and the Mg2+ and Ca2+ requirements of phosphatidate phosphohydrolase in cytosolic and microsomal fractions of rat liver

1987 • 55 citations

Effects of okadaic acid on the activities of two distinct phosphatidate phosphohydrolases in rat hepatocytes

1992 • 54 citations

The regulatory role of EF-hand motifs of pig 80K diacylglycerol kinase as assessed using truncation and deletion mutants

1991 • 51 citations

A novel mechanism for acetylcholine to generate diacylglycerol in brain.

1990 • 50 citations

Divergent effects of propranolol on neutrophil superoxide release: Involvement of phosphatidic acid and diacylglycerol as second messengers

1991 • 49 citations

Phorbol ester-stimulated hydrolysis of phosphatidylcholine and phosphatidylethanolamine by phospholipase D in HeLa cells. Evidence that the basal turnover of phosphoglycerides does not involve phospholipase D.

1991 • 47 citations

Occurrence of immunoreactive 80 kDa and non-immunoreactive diacylglycerol kinases in different pig tissues.

1988 • 46 citations

Bimodal distribution of phosphatidic acid phosphohydrolase in NG108–15 cells

1992 • 30 citations

Counter-regulatory effects of phosphatidic acid on protein kinase C activity in the presence of calcium and diolein

1990 • 29 citations

The effects of Triton X-100 and chlorpromazine on the Mg2+-dependent and Mg2+-independent phosphatidate phosphohydrolase activities of rat lung

1989 • 19 citations

Rapid hydrolysis of diacylglycerol formed during phosphatidate phosphatase assay by lipase activities in rat liver cytosol and microsomes

1989 • 14 citations