Sphingosine inhibits phosphatidate phosphohydrolase in human neutrophils by a protein kinase C-independent mechanism

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Functions of Sphingolipids and Sphingolipid Breakdown Products in Cellular Regulation

1989 • 1,251 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Sphingomyelin turnover induced by vitamin D3 in HL-60 cells

1989 • 629 citations

Lysosphingolipids Inhibit Protein Kinase C: Implications for the Sphingolipidoses

1987 • 593 citations

Growth factor-like action of phosphatidic acid

1986 • 531 citations

Phosphatidylcholine Hydrolysis by Phospholipase D Determines Phosphatidate and Diglyceride Levels in Chemotactic Peptide-stimulated Human Neutrophils

1989 • 429 citations

Cellular ras activity and phospholipid metabolism

1988 • 331 citations

Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst.

1986 • 294 citations

Regulation of Phospholipase D in HL-60 Granulocytes

1989 • 250 citations

Sphingosine stimulates cellular proliferation via a protein kinase C-independent pathway.

1990 • 230 citations

Intracellular translocation of phosphatidate phosphohydrolase and its possible role in the control of glycerolipid synthesis

1984 • 228 citations

Phosphatidic acid may stimulate membrane receptors mediating adenylate cyclase inhibition and phospholipid breakdown in 3T3 fibroblasts.

1987 • 219 citations

1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells.

1987 • 211 citations

Regulation of phospholipid metabolism in differentiating cells from rat brain cerebral hemispheres in culture. Patterns of acetylcholine phosphocholine, and choline phosphoglycerides labeling from (methyl-14C)choline.

1976 • 164 citations

Formation of diacylglycerol by a phospholipase D-phosphatidate phosphatase pathway specific for phosphatidylcholine in endothelial cells

1988 • 149 citations

Activation of phospholipase D by sphingoid bases in NG108-15 neural-derived cells.

1990 • 134 citations

Free Sphingosine Formation from Endogenous Substrates by a Liver Plasma Membrane System with a Divalent Cation Dependence and a Neutral pH Optimum

1989 • 102 citations

Complement C5a activation of phospholipase D in human neutrophils. A major route to the production of phosphatidates and diglycerides.

1990 • 101 citations

Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors.

1988 • 97 citations

Mg2+-dependent phosphatidate phosphohydrolase of rat lung: Development of an assay employing a defined chemical substrate which reflects the phosphohydrolase activity measured using membrane-bound substrate

1985 • 94 citations

Phospholipase D in homogenates from HL-60 granulocytes: Implications of calcium and G protein control

1989 • 91 citations

Phorbol diesters and dioctanoylglycerol stimulate accumulation of both diacylglycerols and alkylacylglycerols in human neutrophils.

1988 • 79 citations

K252a, a new inhibitor of protein kinase C, concomitantly inhibits 40K protein phosphorylation and seroton in secretion in a phorbol ester-stimulated platelets

1987 • 61 citations

Sphingosine inhibits thyrotropin-releasing hormone binding to pituitary cells by a mechanism independent of protein kinase C.

1988 • 56 citations

Phorbol-12-myristate-13-acetate activation of phospholipase D in human neutrophils leads to the production of phosphatides and diglycerides

1990 • 48 citations

Protein kinase C inhibition by sphingoid long-chain bases: Effects on secretion in human neutrophils

1987 • 42 citations

Persistent activity modification of phosphatidate phosphohydrolase and fatty acyl‐CoA synthetase on incubation of adipocytes with the tumour promoter 12‐O‐tetradecanoylphorbol 13‐acetate

1985 • 17 citations