Non‐Genomic Mechanisms of Action of Steroid Hormones

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

1985 • 1,911 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

‘Pheromones’: a New Term for a Class of Biologically Active Substances

1959 • 1,320 citations

Neuroactive steroids

1992 • 1,260 citations

Neurosteroids: Endogenous bimodal modulators of the GABAA receptor mechanism of action and physiological significance

1992 • 1,098 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Molecular biology of GABA _A receptors

1990 • 947 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells

1977 • 686 citations

A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization.

1966 • 680 citations

Dopaminergic and Ligand-Independent Activation of Steroid Hormone Receptors

1991 • 577 citations

A corticosteroid Receptor in Neuronal Membranes

1991 • 522 citations

Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor.

1991 • 521 citations

Molecular cloning and charcterization of rat estrogen receptor cDNA

1987 • 488 citations

Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

1991 • 464 citations

Long-term and short-term electrophysiological effects of estrogen on the synaptic properties of hippocampal CA1 neurons

1992 • 449 citations

A new, nongenomic estrogen action: the rapid release of intracellular calcium.

1992 • 372 citations

Steroid binding to synaptic plasma membrane: Differential binding of glucocorticoids and gonadal steroids

1983 • 349 citations

Cell surface-binding sites for progesterone mediate calcium uptake in human sperm.

1991 • 291 citations

Membrane Effects of Thyrotropin-Releasing Hormone and Estrogen Shown by Intracellular Recording from Pituitary Cells

1979 • 282 citations

Androgens increase intracellular calcium concentration and inositol 1,4,5-trisphosphate and diacylglycerol formation via a pertussis toxin-sensitive G-protein.

1994 • 281 citations

Progesterone modulates a neuronal nicotinic acetylcholine receptor.

1992 • 272 citations

Non-genomic effects of steroids Interactions of steroid molecules with membrane structures and functions

1983 • 268 citations

Steroid-induced meiotic division in Xenopus laevis oocytes: surface and calcium

1978 • 268 citations

Mechanism of the Rapid Effect of 17β-Estradiol on Medial Amygdala Neurons

1986 • 266 citations

STEROIDS AND CELL SURFACES

1961 • 265 citations

A novel zinc finger coiled-coil domain in a family of nuclear proteins

1992 • 260 citations

Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene.

1988 • 246 citations

Progesterone inhibits membrane-bound adenylate cyclase in Xenopus laevis oocytes

1981 • 218 citations

Mechanism of Mineral Formation in Bone

1990 • 210 citations

An influx of extracelluar calcium is required for initiation of the human sperm acrosome reaction induced by human follicular fluid

1988 • 207 citations

Steroid modulation of the GABA/benzodiazepine receptor-linked chloride lonophore

1988 • 187 citations

Estrogen receptors in dendrites and axon terminals in the guinea pig hypothalamus.

1992 • 180 citations

Olfactory receptors are displayed on dog mature sperm cells.

1993 • 179 citations

Glucocorticoid Receptor-Like Antigen in Lymphoma Cell Membranes: Correlation to Cell Lysis

1987 • 177 citations

Plasma Steroid-Binding Proteins

1991 • 177 citations

Cell signaling and estrogens in female rat osteoblasts: A possible involvement of unconventional nonnuclear receptors

1993 • 175 citations

Olfaction in humans with special reference to odorous 16-androstenes: their occurrence, perception and possible social, psychological and sexual impact

1993 • 175 citations

INTERACTION OF NUCLEIC ACIDS, I. PHYSICAL BINDING OF THYMINE, ADENINE, STEROIDS, AND AROMATIC HYDROCARBONS TO NUCLEIC ACIDS

1964 • 174 citations

Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein.

1993 • 163 citations

Partial purification and characterization of oestrogen receptors in subfractions of hepatocyte plasma membranes

1980 • 160 citations

Guanyl nucleotides modulate binding to steroid receptors in neuronal membranes.

1992 • 153 citations

The human vomeronasal system

1994 • 152 citations

A new, nongenomic estrogen action: the rapid release of intracellular calcium

1992 • 151 citations

rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1.

1988 • 150 citations

Development of a highly efficient expression cDNA cloning system: application to oncogene isolation.

1991 • 145 citations

Characterization of membrane receptor activity for 17α,20β,21-trihydroxy-4-pregnen-3-one in ovaries of spotted seatrout (Cynoscion nebulosus)

1990 • 139 citations

The specificity of the response of preoptic-septal area neurons to estrogen: 17?-estradiol versus 17?-estradiol and the response of extrahypothalamic neurons

1977 • 136 citations

Studies on the mechanism of action of estrogens.

1958 • 132 citations

Progesterone receptor characterized by photoaffinity labelling in the plasma membrane of Xenopus laevis oocytes

1984 • 109 citations

A cell line (HBL-100) established from human breast milk

1982 • 108 citations

A specific membrane binding protein for progesterone in rat brain: sex differences and induction by estrogen.

1993 • 107 citations

Locally applied estrogens potentiate glutamate-evoked excitation of cerebellar Purkinje cells

1988 • 107 citations

Ultrastructural localization of the progesterone receptor by an immunogold method: effect of hormone administration.

1986 • 106 citations

Latent transforming growth factor-beta is produced by chondrocytes and activated by extracellular matrix vesicles upon exposure to 1,25-(OH)2D3.

1994 • 102 citations

Progesterone and RU486: opposing effects on human sperm.

1994 • 102 citations

Evidence for a Specific Estradiol Binding Site on Rat Pituitary Membranes

1986 • 101 citations

Expression of the K-fgf proto-oncogene is controlled by 3' regulatory elements which are specific for embryonal carcinoma cells.

1990 • 93 citations

17 beta-estradiol mimics ligand activity of the c-erbB2 protooncogene product.

1993 • 89 citations

A unique bipartite cysteine-histidine motif defines a subfamily of potential zinc-finger proteins

1991 • 82 citations

The interfacial activity of steroid hormones and synthetic estrogens

1957 • 67 citations

Androgen receptors: Structures, mutations, antibodies and cellular dynamics

1989 • 64 citations

A progesterone metabolite stimulates the release of gonadotropin-releasing hormone from GT1-1 hypothalamic neurons via the gamma-aminobutyric acid type A receptor.

1995 • 63 citations

Cell membrane, a target for steroid hormones

1978 • 62 citations

Studies of a plasma membrane steroid receptor in Xenopus oocytes using the synthetic progestin RU 486

1985 • 57 citations

Size and steroid-binding characterization of membrane-associated glucocorticoid receptor in S-49 lymphoma cells

1991 • 52 citations

Isolation of estrogen receptor-binding sites in human genomic DNA

1991 • 49 citations

Aldosterone-specific membrane receptors and rapid non-genomic actions of mineralocorticoids

1992 • 47 citations

Does the guanine nucleotide regulatory protein Ni mediate progesterone inhibition of Xenopus oocyte adenylate cyclase?

1984 • 45 citations

Molecular biology of egg maturation

1984 • 45 citations

Coordinate regulation of glucocorticoid receptor and c-jun mRNA levels: evidence for cross-talk between two signaling pathways' at the transcriptional level.

1994 • 44 citations

Non-reproductive actions of sex steroids

1996 • 37 citations

Receptor transformation, the key to estrogen action

1975 • 26 citations

Coordinate regulation of glucocorticoid receptor and c-jun mRNA levels: evidence for cross-talk between two signaling pathways' at the transcriptional level

1994 • 22 citations

Inhibition of Hypothalamic and Pituitary Muscarinic Receptor Binding by Progesterone

1988 • 21 citations

Membrane Receptors for Aldosterone: A New Concept of Nongenomic Mineralocorticoid Action

1993 • 14 citations