Androgen receptors: Structures, mutations, antibodies and cellular dynamics

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

Steroid 5α-Reductase Deficiency in Man: An Inherited Form of Male Pseudohermaphroditism

1974 • 1,241 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

A homologous protein-coding sequence in drosophila homeotic genes and its conservation in other metazoans

1984 • 920 citations

Molecular Cloning of Human and Rat Complementary DNA Encoding Androgen Receptors

1988 • 908 citations

Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA

1986 • 722 citations

The Human Androgen Receptor: Complementary Deoxyribonucleic Acid Cloning, Sequence Analysis and Gene Expression in Prostate

1988 • 575 citations

Polyadenylic Acid Sequences: Role in Conversion of Nuclear RNA into Messenger RNA

1971 • 569 citations

X-linked Gene for Testicular Feminization in the Mouse

1970 • 551 citations

A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily.

1988 • 532 citations

Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors.

1988 • 530 citations

Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein.

1985 • 492 citations

Characterization and expression of a cDNA encoding the human androgen receptor.

1989 • 483 citations

Genomic organization of the human oestrogen receptor gene.

1988 • 480 citations

Common non-hormone binding component in non-transformed chick oviduct receptors of four steroid hormones

1984 • 442 citations

Segmental distribution of bithorax complex proteins during Drosophila development

1985 • 397 citations

Cloning, structure and expression of a cDNA encoding the human androgen receptor

1988 • 371 citations

Androgen receptor locus on the human X chromosome: regional localization to Xq11-12 and description of a DNA polymorphism.

1989 • 301 citations

The segmentation and homeotic gene network in early Drosophila development

1987 • 286 citations

The Rat Androgen Receptor: Primary Structure, Autoregulation of its Messenger Ribonucleic Acid, and Immunocytochemical Localization of the Receptor Protein

1988 • 277 citations

Relationship of the 90-kDa murine heat shock protein to the untransformed and transformed states of the L cell glucocorticoid receptor.

1987 • 267 citations

The N-terminal DNA-binding ‘zinc finger’ of the oestrogen and glucocorticoid receptors determines target gene specificity.

1988 • 265 citations

Messenger and Heterogeneous Nuclear RNA in HeLa Cells: Differential Inhibition by Cordycepin

1970 • 253 citations

Receptor-Proteins for Androgens and the Mode of Action of Androgens on Gene Transcription in Ventral Prostate

1970 • 246 citations

Activation of the glucocorticoid-receptor complex

1982 • 224 citations

Deletion of the steroid-binding domain of the human androgen receptor gene in one family with complete androgen insensitivity syndrome: evidence for further genetic heterogeneity in this syndrome.

1988 • 206 citations

Cellular Receptors and Mechanisms of Action of Steroid Hormones

1975 • 192 citations

Immunological evidence that the nonhormone binding component of avian steroid receptors exists in a wide range of tissues and species

1985 • 188 citations

Locus on human X chromosome for dihydrotestosterone receptor and androgen insensitivity.

1975 • 182 citations

Part II. Androgen Metabolism and Mechanism of Action in Male Pseudohermaphroditism: A Study of Testicular Feminization

1973 • 180 citations

Regulation of growth hormone messenger RNA synthesis by dexamethasone and triiodothyronine

1985 • 173 citations

STRUCTURAL ORGANIZATION OF THE HUMAN ANDROGEN RECEPTOR GENE

1989 • 165 citations

Hormone-dependent phosphorylation of the 1,25-dihydroxyvitamin D3 receptor in mouse fibroblasts

1985 • 142 citations

Regulation of messenger RNA stability in eukaryotic cells

1987 • 139 citations

The N-terminal domain of the human androgen receptor is encoded by one, large exon

1989 • 136 citations

The nuclear-bound form of the progesterone receptor is generated through a hormone-dependent phosphorylation

1985 • 132 citations

Effect of androgen on the transcription of rat prostatic binding protein genes

1982 • 127 citations

A human 200-kDa protein binds selectively to DNA fragments containing G.T mismatches.

1988 • 126 citations

Evidence for intracellular association of the glucocorticoid receptor with the 90-kDa heat shock protein.

1988 • 124 citations

Identification of a new member of the steroid receptor super-family by cloning and sequence analysis

1988 • 116 citations

RNA-dependent release of androgen and other steroidreceptor complexes from DNA.

1980 • 116 citations

Structure of the chromosomal chicken progesterone receptor gene.

1987 • 108 citations

Newly formed mRNA lacking polyadenylic acid enters the cytoplasm and the polyribosomes but has a shorter half-life in the absence of polyadenylic acid.

1982 • 108 citations

Progression to steroid insensitivity can occur irrespective of the presence of functional steroid receptors

1987 • 105 citations

Ribonucleoprotein Binding of Steroid-“Receptor” Complexes

1973 • 104 citations

Association of the Uterine 17β-Estradiol-Receptor Complex with Ribonucleoprotein in Vitro and in Vivo

1974 • 102 citations

Characterization of a hormone receptor defect in the androgen-insensitivity mutant

1974 • 102 citations

Effects of RNA and ribonuclease on the binding of estrogen and glucocorticoid receptors from MCF-7 cells to DNA-cellulose.

1982 • 93 citations

Inactivation of oestrogen receptor in vitro by nuclear dephosphorylation

1981 • 93 citations

Nuclear RNA is spliced in the absence of poly(A) addition

1981 • 84 citations

Isolation and characterization of human TR3 receptor: A member of steroid receptor superfamily

1989 • 84 citations

A mutation that causes lability of the androgen receptor under conditions that normally promote transformation to the DNA-binding state.

1984 • 79 citations

The Effects of Ribonuclease on Rat Liver Dexamethasone Receptor: Increased Affinity for Deoxyribonucleic Acid and Altered Sedimentation Profile*

1983 • 75 citations

RNA inhibits estrogen receptor binding to DNA.

1981 • 73 citations

Nuclear Concentration of Androgens in Rat Seminal Vesicles and Prostate Demonstrated by Dry-Mount Autoradiography1¹

1970 • 69 citations

Kinetics of Calcium Transport by Fragmented Sarcoplasmic Reticulum

1970 • 67 citations

Biochemistry of steroid hormones

1977 • 66 citations

Translation of Glucocorticoid Receptor mRNA in Vitro Yields a Nonactivated Protein

1989 • 65 citations

RNA induced reversal of glucocorticoid receptor activation

1982 • 62 citations

Purification and structural analysis of the modulator of the glucocorticoid-receptor complex. Evidence that modulator is a novel phosphoglyceride.

1988 • 60 citations

Chick heat-shock protein of Mr = 90,000, free or released from progesterone receptor, is in a dimeric form

1989 • 60 citations

Activation of cytosolic glucocorticoid-receptor complexes in intact WEHI-7 cells does not dephosphorylate the steroid-binding protein.

1987 • 57 citations

Sexual Differentiation: Early Hormone Synthesis and Action1

1980 • 53 citations

Prostate androgen receptor: Immunohistological localization and MRNA characterization

1989 • 50 citations

The use of a hydroxylapatite-filter steroid receptor assay method in the study of the modulation of androgen receptor interaction

1984 • 48 citations

Steroid hormone regulation of the gene encoding the chicken heat shock protein hsp 108.

1987 • 45 citations

Autoimmune anti-androgen-receptor antibodies in human serum.

1985 • 37 citations

The possible role of disulfide bond reduction in transformation of the 10 S androgen receptor.

1986 • 36 citations

Cordycepin and xylosyladenine: Inhibitors of methylation of nuclear RNA

1978 • 36 citations

Intracellular inactivation, reactivation and dynamic status of prostate androgen receptors

1982 • 34 citations

Phosphorylation of glucocorticoid receptor-associated and free forms of the ∼90-kDa heat shock protein before and after receptor activation

1989 • 34 citations

Inhibition of ribonucleic acid efflux from isolated SV40-3T3 cell nuclei by 3′-deoxyadenosine (cordycepin)

1979 • 33 citations

Monoclonal Antibodies against the Androgen Receptor: Recognition of Human and Other Mammalian Androgen Receptors*

1988 • 30 citations

Messenger RNA Stabilization and Gene Transcription in the Estrogen Induction of Vitellogenin mRNA

1985 • 26 citations

Genetics of Steroid Receptors and Their Disorders

1987 • 24 citations

Stabilization of glucocorticoid receptor association with RNA by a low molecular weight factor from rat liver cytosol

1985 • 24 citations

Properties of an intermediate-sized androgen receptor: association with RNA

1986 • 23 citations

Interaction of RNA with transformed glucocorticoid receptor. II. Identification of the RNA as transfer RNA.

1987 • 22 citations

A new method for labeling and autoradiographic localization of androgen receptors.

1987 • 21 citations

Estradiol-stimulated nuclear ribonucleoprotein transport in the rat uterus: a molecular basis

1988 • 18 citations

Nucleocytoplasmic transport of RNA. The effect of 3′-deoxyadenosine triphosphate on RNA release from isolated nuclei

1980 • 17 citations

Establishment of Monoclonal Antibody to Human Androgen Receptor and Its Clinical Application for Prostatic Cancers

1988 • 17 citations

Inhibition of the phosphorylation of non-histone chromosomal proteins of rat liver by cordycepin and cordycepin triphosphate.

1978 • 17 citations

Similarity between tyrosyl‐tRNA synthetase and the estrogen receptor

1989 • 14 citations

Resolution of non-activated and activated androgen receptors based on differences in their hydrodynamic properties

1985 • 13 citations

Glucocorticoid receptors are associated with particles containing DNA and RNA in vivo

1987 • 12 citations

RNA-containing nuclear binding sites for glucocorticoid-receptor complexes

1984 • 12 citations

Association of RNA with the Glucocorticoid Receptor and Possible Role in Activation

1986 • 10 citations

Glucocorticoid-receptor complexes are associated with small RNA in vitro

1989 • 9 citations

Quantitative ultrastructural autoradiographic study of RNA transport in rat ventral prostate

1986 • 8 citations

Intracellular inhibition of chromatin binding and transformation of androgen receptor by 3′-deoxyadenosine.

1988 • 4 citations