A novel property of a mitochondrial presequence

Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential

1985 • 2,037 citations

Mitochondrial targeting sequences may form amphiphilic helices.

1986 • 1,019 citations

Mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles

1974 • 949 citations

A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers.

1986 • 493 citations

Transport of proteins into mitochondria: Translocational intermediates spanning contact sites between outer and inner membranes

1985 • 470 citations

Mitochondrial contact sites. Lipid composition and dynamics.

1990 • 426 citations

70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria.

1988 • 380 citations

Role of an energized inner membrane in mitochondrial protein import. Delta psi drives the movement of presequences.

1991 • 372 citations

Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria.

1982 • 351 citations

Improved methods to isolate and subfractionate rat liver mitochondria. Lipid composition of the inner and outer membrane

1990 • 348 citations

Requirement of a Membrane Potential for the Posttranslational Transfer of Proteins into Mitochondsria

1982 • 292 citations

Amphiphilicity is essential for mitochondrial presequence function.

1988 • 274 citations

Cytoplasmic type 80S ribosomes associated with yeast mitochondria. IV. Attachment of ribosomes to the outer membrane of isolated mitochondria.

1975 • 262 citations

Transport of proteins into mitochondria: a potassium diffusion potential is able to drive the import of ADP/ATP carrier.

1985 • 245 citations

A leader peptide is sufficient to direct mitochondrial import of a chimeric protein.

1985 • 239 citations

The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix.

1984 • 236 citations

Both ATP and an energized inner membrane are required to import a purified precursor protein into mitochondria.

1987 • 206 citations

Phosphodiester bond cleavage outside mitochondria is required for the completion of protein import into the mitochondrial matrix

1987 • 175 citations

A dynamic model of the mitochondrial protein import machinery

1992 • 160 citations

Mitochondrial membrane contact sites of yeast. Characterization of lipid components and possible involvement in intramitochondrial translocation of phospholipids

1991 • 138 citations

Import of cytochrome c heme lyase into mitochondria: a novel pathway into the intermembrane space.

1992 • 133 citations

[65] The use of optical probes to monitor membrane potential

1979 • 122 citations

Adriamycin, a drug interacting with acidic phospholipids, blocks import of precursor proteins by isolated yeast mitochondria

1989 • 120 citations

Polymorphic regulation of membrane lipid composition

1987 • 110 citations

Protein import into the yeast mitochondrial matrix. A new translocation intermediate between the two mitochondrial membranes.

1991 • 107 citations

Membrane insertion and lateral diffusion of fluorescence-labelled cytochrome c oxidase subunit IV signal peptide in charged and uncharged phospholipid bilayers

1990 • 95 citations

Incorporation of a synthetic mitochondrial signal peptide into charged and uncharged phospholipid monolayers

1986 • 90 citations

Mitochondrial preproteins en route from the outer membrane to the inner membrane are exposed to the intermembrane space

1991 • 90 citations

Polymorphic phase behaviour of cardiolipin from bovine heart and from Bacillus subtilis as detected by 31P-NMR and freeze-fracture techniques

1982 • 87 citations

Structural analysis and amphiphilic properties of a chemically synthesized mitochondrial signal peptide.

1986 • 83 citations

The cytosolic factor required for import of precursors of mitochondrial proteins into mitochondria.

1988 • 82 citations

Effects of Synthetic Model Peptides Resembling the Extension Peptides of Mitochondrial Enzyme Precursors on Import of the Precursors into Mitochondria1

1985 • 75 citations

Specific Binding of Mitochondrial Protein Precursors to Liposomes Containing Cardiolipin1

1988 • 69 citations

Melittin induces HII phase formation in cardiolipin model membranes

1987 • 67 citations

Interaction of melittin with negatively charged phospholipids: Consequences for lipid organization

1987 • 65 citations

Presequence binding factor-dependent and -independent import of proteins into mitochondria.

1992 • 63 citations

Targeting of a chemically pure preprotein to mitochondria does not require the addition of a cytosolic signal recognition factor.

1992 • 55 citations

Sequential translocation of an artificial precursor protein across the two mitochondrial membranes.

1992 • 48 citations

Modulation of membrane surface curvature by peptide-lipid interactions

1988 • 48 citations

Isolation and purification of cardiolipin from beef heart.

1985 • 46 citations

The effect of a membrane potential on the interaction of mastoparan X, a mitochondrial presequence, and several regulatory peptides with phospholipid vesicles

1991 • 43 citations

Binding of a mitochondrial presequence to natural and artificial membranes: role of surface potential

1992 • 43 citations

Secondary structure of a mitochondrial signal peptide in lipid bilayer membranes

1990 • 43 citations

The Phosphatide Composition of a Purified Cytochrome Oxidase Preparation

1958 • 42 citations

Import of proteins into mitochondria. Isolated yeast mitochondria and a solubilized matrix protease correctly process cytochrome c oxidase subunit V precursor at the NH2 terminus.

1983 • 40 citations

Interaction of peptides corresponding to mitochondrial presequences with membranes.

1991 • 33 citations

Presence of the cytosolic factor stimulating the import of precursor of mitochondrial proteins in rabbit reticulocytes and rat liver cells

1990 • 25 citations

Ion gradient-induced membrane translocation of model peptides

1991 • 21 citations

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