Activation of the growth arrest and DNA damage-inducible gene gadd 153 by nephrotoxic cysteine conjugates and dithiothreitol.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Oncogenes and signal transduction

1991 • 2,816 citations

Epidermal growth factor.

1990 • 1,645 citations

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli

1984 • 1,608 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

PRIMARY RESPONSE GENES INDUCED BY GROWTH FACTORS AND TUMOR PROMOTERS

1991 • 1,078 citations

Abnormal Proteins Serve as Eukaryotic Stress Signals and Trigger the Activation of Heat Shock Genes

1986 • 904 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation

1990 • 869 citations

Growth factors in development, transformation, and tumorigenesis

1991 • 695 citations

REGULATION AND EXPRESSION OF THE ADAPTIVE RESPONSE TO ALKYLATING AGENTS

1988 • 645 citations

The origin and characteristics of a pig kidney cell strain, LLC-PK1

1976 • 604 citations

INDUCIBLE DNA REPAIR SYSTEMS

1985 • 586 citations

The cyclic AMP-mediated stimulation of cell proliferation

1989 • 464 citations

Poly(A), poly(A) binding protein and the regulation of mRNA stability

1989 • 355 citations

REGULATED mRNA STABILITY

1990 • 279 citations

Transforming growth factor-β: Multiple effects on cell differentiation and extracellular matrices

1988 • 271 citations

Mechanisms of cell death

1989 • 237 citations

SIGNAL TRANSDUCTION BY GUANYLYL CYCLASES

1991 • 217 citations

Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity

1986 • 208 citations

The role of calcium in cell killing

1990 • 199 citations

Activation of the gadd153 promoter by genotoxic agents: a rapid and specific response to DNA damage.

1992 • 175 citations

A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K.

1986 • 153 citations

Bioactivation of Nephrotoxic Haloalkenes by Glutathione Conjugation: Formation of Toxic and Mutagenic Intermediates by Cysteine Conjugate β-Lyase

1989 • 151 citations

RNA metabolism: strategies for regulation in the heat shock response

1990 • 142 citations

The role of calcium in lethal cell injury

1990 • 128 citations

Isolation and characterization of the hamster gadd153 gene. Activation of promoter activity by agents that damage DNA.

1990 • 120 citations

Phosphatidylinositol-Derived Precursors and Signals

1990 • 103 citations

The role of glutathione conjugate metabolism and cysteine conjugate beta-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells.

1986 • 103 citations

Review of the current status of calcium and thiols in cellular injury

1990 • 98 citations

The mechanism of cysteine conjugate cytotoxicity in renal epithelial cells. Covalent binding leads to thiol depletion and lipid peroxidation.

1990 • 97 citations

Reactivity of the phosphopyridoxal groups of cystathionase.

1976 • 92 citations

Cysteine conjugate toxicity, metabolism, and binding to macromolecules in isolated rat kidney mitochondria.

1990 • 79 citations

Molecular and biochemical mechanisms of chemically induced nephrotoxicity: a review

1990 • 76 citations

Perturbations of intracellular calcium distribution in kidney cells by nephrotoxic haloalkenyl cysteine S-conjugates.

1990 • 51 citations

Inhibition of iodoacetamide and t-butylhydroperoxide toxicity in LLC-PK1 cells by antioxidants: A role for lipid peroxidation in alkylation induced cytotoxicity

1991 • 51 citations

Oncogenes and cellular signal transduction

1989 • 44 citations

Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine

1991 • 27 citations