Correlation between two effects of high density lipoproteins on vascular endothelial cells. The induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and the support of cellular proliferation.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1977 • 2,481 citations

Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth.

1980 • 1,195 citations

Regulation of Plasma Cholesterol by Lipoprotein Receptors

1981 • 958 citations

Receptor-Mediated Control of Cholesterol Metabolism

1976 • 957 citations

Regulation of HMG-CoA Reductase

1976 • 743 citations

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

1978 • 556 citations

Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity in Cultured Human Fibroblasts

1974 • 545 citations

Purification of the fibroblast growth factor activity from bovine brain.

1978 • 498 citations

Clonal growth of bovine vascular endothelial cells: fibroblast growth factor as a survival agent.

1976 • 423 citations

Relative importance of high and low density lipoproteins in the regulation of cholesterol synthesis in the adrenal gland, ovary, and testis of the rat.

1978 • 386 citations

Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1980 • 353 citations

Subfractionation of human high density lipoproteins by heparin-Sepharose affinity chromatography.

1980 • 349 citations

Stimulation of corneal endothelial cell proliferation in vitro by fibroblast and epidermal growth factors

1977 • 335 citations

Essential role for mevalonate synthesis in DNA replication

1979 • 297 citations

3-Hydroxy-3-methylglutaryl Coenzyme A Reductase

1973 • 240 citations

Extracellular Matrix and Control of Proliferation of Vascular Endothelial Cells

1980 • 229 citations

The role of high density lipoproteins in rat adrenal cholesterol metabolism and steroidogenesis.

1980 • 229 citations

Sterol Biosynthesis

1981 • 206 citations

Cholesterol content and sterol synthesis in human skin fibroblasts and rat aortic smooth muscle cells exposed to lipoprotein-depleted serum and high density apolipoprotein/phospholipid mixtures

1976 • 196 citations

Inhibition of cholesterol synthesis with compactin renders growth of cultured cells dependent on the low density lipoprotein receptor.

1979 • 186 citations

Effect of high and low density lipoproteins on proliferation of cultured bovine vascular endothelial cells.

1980 • 185 citations

Biochemistry of Polyisoprenoid Biosynthesis

1976 • 178 citations

Role of contact inhibition in the regulation of receptor-mediated uptake of low density lipoprotein in cultured vascular endothelial cells.

1978 • 177 citations

Factors controlling the proliferative rate, final cell density, and life span of bovine vascular smooth muscle cells in culture.

1981 • 156 citations

Body Cholesterol Removal: Role of Plasma High-Density Lipoproteins1 1Supported by National Health Service Grants HL 18673, HL 07291, and HL 22682, and a Grant-In-Aid from the American Heart Association (316–3070–2286).

1980 • 156 citations

Synthesis of ubiquinone and cholesterol in human fibroblasts: Regulation of a branched pathway

1979 • 152 citations

Control of proliferation of bovine vascular endothelial cells

1977 • 139 citations

Separate mechanisms for the uptake of high and low density lipoproteins by mouse adrenal gland in vivo.

1979 • 136 citations

Isopentenyladenine as a mediator of mevalonate-regulated DNA replication.

1980 • 91 citations

Effect of contact inhibition on the regulation of cholesterol metabolism in cultured vascular endothelial cells.

1979 • 88 citations

High density lipoproteins and the growth of vascular endothelial cells in serum-free medium

1981 • 76 citations

Control of sterol synthesis and of hydroxymethylglutaryl CoA reductase in skin fibroblasts grown from patients with homozygous type II hyperlipoproteinemia

1975 • 75 citations

Characteristics of chylomicron binding and lipid uptake by endothelial cells in culture.

1979 • 73 citations

Factors involved in the control of proliferation of bovine corneal endothelial cells maintained in serum‐free medium

1982 • 67 citations

Kinetic parameters of the lipoprotein transport systems in the adrenal gland of the rat determined in vivo. Comparison of low and high density lipoproteins of human and rat origin.

1981 • 67 citations

Up‐Regulation in Vascular Endothelial Cells of Binding Sites of High Density Lipoppppprotein Induced by 25‐Hydroxycholesterol

1981 • 65 citations

The coating of bovine and rabbit corneas denuded of their endothelium with bovine corneal endothelial cells

1979 • 64 citations

Biological and pharmacological activity of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase

1981 • 56 citations

Effect of cell density and confluency on cholesterol metabolism in cancer cells in monolayer culture.

1981 • 55 citations

Stimulation and suppression of 3-hydroxy-3-methylglutaryl coenzyme a reductase in normal human fibroblasts by high density lipoprotein subclasses

1980 • 49 citations

The Interaction of the High‐Density Lipoprotein with Cultured Cells of Bovine Vascular Endothelium

1981 • 47 citations

The activity of 3-hydroxy-3-methylglutaryl coenzyme a reductase and the rate of sterol synthesis diminish in cultures with high cell density

1981 • 42 citations

The contribution of the cholesterol biosynthetic pathway to intermediary metabolism and cell function

1981 • 25 citations

Changes in sterol biosynthesis accompanying cessation of glial cell growth in serum-free medium

1980 • 16 citations

Changes in synthesis of sterols and fatty acids associated with inhibition of growth of L-M cells at high cell density

1981 • 15 citations