Subtype-specific Translocation of Diacylglycerol Kinase α and γ and Its Correlation with Protein Kinase C

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

1992 • 4,480 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

1986 • 999 citations

Diglyceride lipase: a pathway for arachidonate release from human platelets.

1979 • 696 citations

Taxonomy and function of C1 protein kinase C homology domains

1997 • 350 citations

Phosphatidic acid activation of protein kinase C-ζ overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids

1994 • 308 citations

Mammalian Diacylglycerol Kinases, a Family of Lipid Kinases with Signaling Functions

1999 • 284 citations

Protein kinase C regulates the nuclear localization of diacylglycerol kinase-ζ

1998 • 256 citations

Direct Visualization of the Translocation of the γ-Subspecies of Protein Kinase C in Living Cells Using Fusion Proteins with Green Fluorescent Protein

1997 • 228 citations

Porcine diacylglycerol kinase sequence has zinc finger and E–F hand motifs

1990 • 218 citations

Molecular Cloning of a Novel Human Diacylglycerol Kinase Highly Selective for Arachidonate-containing Substrates

1996 • 205 citations

The regulation of phospholipase C-gamma 1 by phosphatidic acid. Assessment of kinetic parameters.

1993 • 181 citations

Molecular Cloning and Characterization of a Novel Human Diacylglycerol Kinase ζ

1996 • 167 citations

Molecular Cloning of a Novel Diacylglycerol Kinase Isozyme with a Pleckstrin Homology Domain and a C-terminal Tail Similar to Those of the EPH Family of Protein-tyrosine Kinases

1996 • 163 citations

A Cytoplasmic Protein Inhibits the GTPase Activity of H-Ras in a Phospholipid-Dependent Manner

1990 • 153 citations

Residues in the Second Cysteine-rich Region of Protein Kinase C δ Relevant to Phorbol Ester Binding as Revealed by Site-directed Mutagenesis

1995 • 149 citations

Distinct Effects of Fatty Acids on Translocation of γ- and ε-Subspecies of Protein Kinase C

1998 • 137 citations

Molecular Basis for Protein Kinase C Isozyme-Selective Binding: The Synthesis, Folding, and Phorbol Ester Binding of the Cysteine-Rich Domains of All Protein Kinase C Isozymes

1998 • 136 citations

Three Distinct Mechanisms for Translocation and Activation of the δ Subspecies of Protein Kinase C

1998 • 135 citations

Molecular cloning and expression of a 90-kDa diacylglycerol kinase that predominantly localizes in neurons.

1993 • 133 citations

Increases in intracellular calcium via activation of an endogenous P₂‐purinoceptor in cultured CHO‐K1 cells

1993 • 132 citations

Porcine 80-kDa diacylglycerol kinase is a calcium-binding and calcium/phospholipid-dependent enzyme and undergoes calcium-dependent translocation.

1991 • 131 citations

Electron microscopic localization of type I protein kinase C in rat Purkinje cells

1988 • 118 citations

Cloning of a Novel Human Diacylglycerol Kinase (DGKθ) Containing Three Cysteine-rich Domains, a Proline-rich Region, and a Pleckstrin Homology Domain with an Overlapping Ras-associating Domain

1997 • 105 citations

Cloning and expression of a cytoskeleton-associated diacylglycerol kinase that is dominantly expressed in cerebellum.

1994 • 99 citations

The Cloning and Characterization of a Novel Human Diacylglycerol Kinase, DGKι

1998 • 82 citations

Translocation of diacylglycerol kinase in response to chemotactic peptide and phorbol ester in neutrophils

1987 • 54 citations

Phosphorylation of diacylglycerol kinase in vitro by protein kinase C

1989 • 53 citations

Purification and Characterization of Diacylglycerol Lipase from Human Platelets

1999 • 51 citations

Phorbol ester-induced translocation of diacylglycerol kinase from the cytosol to the membrane in Swiss 3T3 fibroblasts

1989 • 50 citations

Phospholipase A2 and its products are involved in the purinergic receptor-mediated translocation of protein kinase C in CHO-K1 cells

2000 • 23 citations

Phosphorylation of pig brain diacylglycerol kinase by endogenous protein kinase

1986 • 19 citations

Variant Forms of Green and Blue Fluorescent Proteins Adapted for the Use in Mammalian Cells

1998 • 17 citations

Receptor-mediated diacylglycerol kinase translocation dependent on both transient increase in the intracellular calcium concentration and modification by protein kinase C

1997 • 10 citations