A Built-in Arginine Finger Triggers the Self-stimulatory GTPase-activating Activity of Rho Family GTPases

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

1997 • 770 citations

Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity.

1990 • 560 citations

Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue

1997 • 487 citations

GTPase-activating proteins: helping hands to complement an active site

1998 • 410 citations

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

1997 • 252 citations

Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.

1990 • 204 citations

Formation of a Transition-State Analog of the Ras GTPase Reaction by Ras·GDP, Tetrafluoroaluminate, and GTPase-Activating Proteins

1996 • 201 citations

The Faciogenital Dysplasia Gene Product FGD1 Functions as a Cdc42Hs-specific Guanine-Nucleotide Exchange Factor

1996 • 158 citations

Characterization of the Interactions between the Small GTPase Cdc42 and Its GTPase-activating Proteins and Putative Effectors

1997 • 99 citations

Actin cytoskeleton organization regulated by the PAK family of protein kinases

1998 • 96 citations

Control of mitotic events by the Cdc42 GTPase, the Clb2 cyclin and a member of the PAK kinase family

1998 • 86 citations

Negative Regulation of Rho Family GTPases Cdc42 and Rac2 by Homodimer Formation

1998 • 83 citations

Regulation of RhoA GTP Hydrolysis by the GTPase-Activating Proteins p190, p50RhoGAP, Bcr, and 3BP-1

1998 • 80 citations

Control of reorganization of the actin cytoskeleton by Rho family small GTP-binding proteins in yeast

1998 • 69 citations

Residues of the Rho Family GTPases Rho and Cdc42 That Specify Sensitivity to Dbl-like Guanine Nucleotide Exchange Factors

1997 • 68 citations

Structural Determinants Required for the Interaction between Rho GTPase and the GTPase-activating Domain of p190

1997 • 68 citations

Interaction of Rac1 with GTPase-activating Proteins and Putative Effectors

1998 • 65 citations

The CDC42 homologue from Caenorhabditis elegans. Complementation of yeast mutation

1993 • 61 citations

Fluoride Activation of the Rho Family GTP-binding Protein Cdc42Hs

1998 • 42 citations

Molecular Characterization of the GTPase-activating Domain of ADP-ribosylation Factor Domain Protein 1 (ARD1)

1998 • 34 citations

Turning off the Ras switch with the flick of a finger

1997 • 18 citations