Activation of Ca2+/calmodulin-dependent protein kinase II and protein kinase C by glutamate in cultured rat hippocampal neurons.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

NMDA receptors - their role in long-term potentiation

1987 • 1,177 citations

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation

1989 • 1,015 citations

[1] Assays of protein kinase

1983 • 832 citations

Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapse.

1985 • 636 citations

Regional distribution of type II Ca2+/calmodulin-dependent protein kinase in rat brain

1985 • 625 citations

Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase.

1983 • 617 citations

Proteolytic activation of calcium-activated, phospholipid-dependent protein kinase by calcium-dependent neutral protease.

1983 • 601 citations

Persistent protein kinase activity underlying long-term potentiation

1988 • 557 citations

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by immunofluorescence in frozen and plastic sections.

1983 • 555 citations

The current excitement in long term potentiation

1988 • 538 citations

Translocation of Protein Kinase C Activity May Mediate Hippocampal Long-Term Potentiation

1986 • 532 citations

The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture

1991 • 463 citations

The activation of inositol phospholipid metabolism as a signal- transducing system for excitatory amino acids in primary cultures of cerebellar granule cells

1986 • 431 citations

Light and electron microscopic studies of the distribution of microtubule‐associated protein 2 in rat brain: A difference between dendritic and axonal cytoskeletons

1984 • 424 citations

Glutamate-induced long-term potentiation of the frequency of miniature synaptic currents in cultured hippocampal neurons

1992 • 421 citations

Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase.

1984 • 389 citations

Postsynaptic factors control the duration of synaptic enhancement in area CA1 of the hippocampus

1991 • 319 citations

MAP2 is localized to the dendrites of hippocampal neurons which develop in culture

1984 • 313 citations

Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons.

1987 • 309 citations

Characterization of synapsin I binding to small synaptic vesicles.

1986 • 304 citations

Immunocytochemical localization of calcium/calmodulin-dependent protein kinase II in rat brain.

1984 • 292 citations

The influence of basic residues on the substrate specificity of protein kinase C.

1987 • 287 citations

Multiple phosphorylation sites in protein I and their differential regulation by cyclic AMP and calcium.

1979 • 284 citations

Sequences of autophosphorylation sites in neuronal type II CaM kinase that control Ca2+-independent activity

1988 • 283 citations

Activation of NMDA receptors induces rapid dephosphorylation of the cytoskeletal protein MAP2

1990 • 220 citations

Identification of the Major Postsynaptic Density Protein as Homologous with the Major Calmodulin‐Binding Subunit of a Calmodulin‐Dependent Protein Kinase

1984 • 220 citations

Ca2+/calmodulin-dependent protein kinase II. Identification of a regulatory autophosphorylation site adjacent to the inhibitory and calmodulin-binding domains.

1988 • 193 citations

Immunohistochemical Localization of Ca²⁺/Calmodulin‐Dependent Protein Kinase II in Rat Brain and Various Tissues

1988 • 185 citations

Ca²⁺, Calmodulin‐Dependent Regulation of Microtubule Formation via Phosphorylation of Microtubule‐Associated Protein 2, τ Factor, and Tubulin, and Comparison with the Cyclic AMP‐Dependent Phosphorylation

1985 • 183 citations

Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity.

1988 • 175 citations

Calcium · calmodulin-dependent protein kinase II and calcium · phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide

1987 • 173 citations

Persistent protein kinase activation in the maintenance phase of long-term potentiation.

1991 • 166 citations

Immunocytochemical localization of beta II subspecies of protein kinase C in rat brain.

1989 • 159 citations

Inhibitors of calmodulin and protein kinase C block different phases of hippocampal long-term potentiation

1988 • 153 citations

Autophosphorylation of type II Ca2+/calmodulin-dependent protein kinase in cultures of postnatal rat hippocampal slices.

1991 • 134 citations

Development and selective neurodegeneration in cell cultures from different hippocampal regions

1989 • 115 citations

Activation of multifunctional Ca2+/calmodulin-dependent kinase in intact hippocampal slices

1991 • 115 citations

Inhibition of Excitatory Amino Acid‐Stimulated Phosphoinositide Hydrolysis in the Neonatal Rat Hippocampus by 2‐Amino‐3‐Phosphonopropionate

1989 • 114 citations

Ca2+/calmodulin-dependent protein kinase II: localization in the interphase nucleus and the mitotic apparatus of mammalian cells.

1990 • 109 citations

Generation of the Ca2+-independent form of Ca2+/calmodulin-dependent protein kinase II in cerebellar granule cells

1989 • 101 citations

Trifluoperazine inhibits hippocampal long-term potentiation and the phosphorylation of a 40,000 dalton protein

1980 • 81 citations

Phencyclidine is a negative allosteric modulator of signal transduction at two subclasses of excitatory amino acid receptors.

1987 • 68 citations

Regional and Temporal Alterations in Ca²⁺/Calmodulin‐Dependent Protein Kinase II and Calcineurin in the Hippocampus of Rat Brain After Transient Forebrain Ischemia

1992 • 65 citations

Monoclonal antibodies against rat brain protein kinase C and their application to immunocytochemistry in nervous tissues

1987 • 64 citations

Serum and growth factors rapidly elicit phosphorylation of the Ca2+/calmodulin-dependent protein kinase II in intact quiescent rat 3Y1 cells.

1988 • 57 citations

Glutamate-stimulated protein phosphorylation in cultured hippocampal pyramidal neurons

1991 • 48 citations

Long-lasting physiological effects of bath applied N-methyl-d-aspartate

1989 • 43 citations

Activation of Ca2+/calmodulin-dependent protein kinase II in cerebellar granule cells by N-methyl-d-aspartate receptor activation

1990 • 41 citations

Regulation of the interaction of actin filaments with microtubule-associated protein 2 by calmodulin-dependent protein kinase II

1988 • 40 citations

Dose-dependent phorbol ester facilitation or blockade of hippocampal long-term potentiation: relation to membrane/cytosol distribution of protein kinase C activity

1989 • 32 citations

Translocation of protein kinase C in rat hippocampal slices

1986 • 28 citations