Priming of the oxidative burst in human neutrophils by physiological agonists or cytochalasin B results from the recruitment of previously non-responsive cells.

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

1983 • 1,808 citations

Stimulation of neutrophils by tumor necrosis factor.

1986 • 847 citations

Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme.

1984 • 612 citations

Cytochalasin B: Effect on Lysosomal Enzyme Release from Human Leukocytes

1973 • 243 citations

Subpopulations of neutrophils with increased oxidative product formation in blood of patients with infection.

1986 • 224 citations

Activation of neutrophils by recombinant interleukin 6

1989 • 222 citations

Lipopolysaccharide priming of human neutrophils for an enhanced respiratory burst. Role of intracellular free calcium.

1989 • 213 citations

Leukotriene production in human neutrophils primed by recombinant human granulocyte/macrophage colony-stimulating factor and stimulated with the complement component C5A and FMLP as second signals.

1988 • 185 citations

Effects of Tumour Necrosis Factor Alpha and Interleukin-1 Alpha and Beta on Human Neutrophil Migration, Respiratory Burst and Degranulation

1988 • 178 citations

Recombinant human tumor necrosis factor-alpha. Regulation of N-formylmethionylleucylphenylalanine receptor affinity and function on human neutrophils.

1988 • 162 citations

Human neutrophil heterogeneity exists, but is it meaningful?

1984 • 134 citations

Tumor necrosis factor alpha priming of phospholipase D in human neutrophils

1991 • 129 citations

The priming of neutrophils by lipopolysaccharide for production of intracellular platelet-activating factor. Potential role in mediation of enhanced superoxide secretion.

1988 • 123 citations

Priming of the human neutrophil respiratory burst by granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha involves regulation at a post-cell surface receptor level. Enhancement of the effect of agents which directly activate G proteins.

1990 • 111 citations

Human Neutrophil Heterogeneity Identified Using Flow Microfluorometry to Monitor Membrane Potential

1981 • 96 citations

Priming of polymorphonuclear neutrophils by tumor necrosis factor alpha in whole blood: identification of two polymorphonuclear neutrophil subpopulations in response to formyl-peptides

1993 • 88 citations

Use of cytochalasin B to distinguish between early and late events in neutrophil activation

1980 • 80 citations

Recombinant human monocyte IL-8 primes NADPH-oxidase and phospholipase A2 activation in human neutrophils.

1992 • 80 citations

Two neutrophil populations in human blood with different chemotactic activities: separation and chemoattractant binding

1982 • 72 citations

Increased Superoxide Generation by Normal Granulocytes Incubated In Sera from Patients with Psoriasis

1981 • 65 citations

Tumor necrosis factor-alpha regulates expression of receptors for formyl-methionyl-leucyl-phenylalanine, leukotriene B4, and platelet-activating factor. Dissociation from priming in human polymorphonuclear neutrophils.

1991 • 62 citations

On the Biological Occurrence and Regulation of 1-Acyl and 1-O-Alkyl-diradylglycerols in Human Neutrophils

1989 • 59 citations

Dynamics of the Diradylglycerol Responses of Stimulated Phagocytes

1989 • 59 citations

Both Recombinant Interleukin-1 (Beta) and Purified Human Monocyte Interleukin-1 Prime Human Neutrophils for Increased Oxidative Activity and Promote Neutrophil Spreading

1989 • 52 citations

The effects of rhGM‐CSF on the neutrophil respiratory burst when studied in whole blood

1990 • 42 citations

The effect of hemodialysis and C5a des arg on neutrophil subpopulations

1980 • 42 citations

Botulinum C₂ toxin potentiates activation of the neutrophil oxidase Further evidence of a role for actin polymerization

1987 • 36 citations

Actin polymerization modifies stimulus-oxidase coupling in rat neutrophils

1987 • 31 citations

Conversion of leukotriene A4 by neutrophils and platelets from patients with atopic dermatitis.

1991 • 30 citations

Involvement of leukotriene B4 and platelet-activating factor in cytokine priming of human polymorphonuclear leucocytes.

1991 • 30 citations

An Elevation in the Concentration of Free Cytosolic Calcium Is Sufficient to Activate the Oxidative Burst of Granulocytes Primed with Recombinant Human Granulocyte-Macrophage Colony-stimulating Factor

1989 • 29 citations

Receptor expression and oxidase activity in human neutrophils: Regulation by granulocyte-macrophage colony-stimulating factor and dependence upon protein biosynthesis

1990 • 27 citations

Homologous priming in chemotactic peptide‐stimulated neutrophils

1993 • 19 citations