On the Biological Occurrence and Regulation of 1-Acyl and 1-O-Alkyl-diradylglycerols in Human Neutrophils

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

1986 • 999 citations

Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis.

1975 • 749 citations

1-O-alkyl-2-arachidonoyl-sn-glycero-3-phosphocholine. A common source of platelet-activating factor and arachidonate in human polymorphonuclear leukocytes.

1984 • 296 citations

R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet.

1985 • 270 citations

A novel mechanism of diglyceride formation. 12-O-tetradecanoylphorbol-13-acetate stimulates the cyclic breakdown and resynthesis of phosphatidylcholine.

1986 • 267 citations

Polyphosphoinositide micelles and polyphosphoinositide-containing vesicles dissociate endogenous gelsolin-actin complexes and promote actin assembly from the fast-growing end of actin filaments blocked by gelsolin.

1987 • 256 citations

The alk-1-enyl group content of mammalian myelin phosphoglycerides by quantitative two-dimensional thin-layer chromatography

1968 • 254 citations

Choline-linked Phosphoglycerides

1989 • 234 citations

1-O-alkyl-linked glycerophospholipids of human neutrophils: distribution of arachidonate and other acyl residues in the ether-linked and diacyl species.

1984 • 173 citations

Activation of phospholipase D by chemotactic peptide in HL-60 granulocytes

1988 • 163 citations

Receptor-cytoskeleton interactions and membrane traffic may regulate chemoattractant-induced superoxide production in human granulocytes.

1986 • 144 citations

Multiple forms of myeloperoxidase from human neutrophilic granulocytes: Evidence for differences in compartmentalization, enzymatic activity, and subunit structure

1983 • 134 citations

Cytochalasin B enhancement of the diacylglycerol response in formyl peptide-stimulated neutrophils.

1986 • 133 citations

Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols

1988 • 128 citations

Sphinganine effects on chemoattractant-induced diacylglycerol generation, calcium fluxes, superoxide production, and on cell viability in the human neutrophil. Delivery of sphinganine with bovine serum albumin minimizes cytotoxicity without affecting inhibition of the respiratory burst.

1988 • 119 citations

Mono- and dimethyl phosphatidates from different subtypes of choline and ethanolamine glycerophosphatides

1968 • 115 citations

Diacylglycerol accumulation and superoxide anion production in stimulated human neutrophils.

1987 • 103 citations

Phorbol myristate acetate (PMA) augments chemoattractant-induced diglyceride generation in human neutrophils but inhibits phosphoinositide hydrolysis. Implications for the mechanism of PMA priming of the respiratory burst.

1988 • 101 citations

Structural and chemical specificity of diradylglycerols for protein kinase C activation

1984 • 92 citations

Differential stimulation of the respiratory burst and lysosomal enzyme secretion in human polymorphonuclear leukocytes by synthetic diacylglycerols.

1986 • 85 citations

Membrane‐cytoskeleton interactions and the regulation of chemotactic peptide‐induced activation of human granulocytes: The effects of dihydrocytochalasin B

1985 • 84 citations

Protein kinase C and cAMP‐dependent protein kinase induce opposite effects on actin polymerizability

1987 • 83 citations

Purified protein kinase C phosphorylates microtubule-associated protein 2.

1986 • 82 citations

Phorbol diesters and dioctanoylglycerol stimulate accumulation of both diacylglycerols and alkylacylglycerols in human neutrophils.

1988 • 79 citations

1-O-hexadecyl-2-acetyl-sn-glycerol stimulates differentiation of HL-60 human promyelocytic leukemia cells to macrophage-like cells

1984 • 65 citations

Studies on ether phospholipids

1984 • 63 citations

Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate.

1987 • 63 citations

Alkyl analogs of diacylglycerol as activators of protein kinase C

1987 • 61 citations

Diacylglycerols enhance human neutrophil degranulation responses: Relevancy to a multiple mediator hypothesis of cell function

1984 • 53 citations

Identification of endogenous 1-O-alk-1'-enyl-2-acyl-sn-glycerol in myocardium and its effective utilization by choline phosphotransferase.

1988 • 49 citations

Vimentin, a cytoskeletal substrate of protein kinase C

1988 • 48 citations

A method for the quantitative determination of glycerolipids containing O-alkyl and O-alk-1-enyl moieties

1975 • 48 citations

Changes in the composition of fatty chains of diacyl, alkylacyl and alkenylacyl ethanolamine and choline phosphoglycerides during the development of chick heart ventricular cells High accumulation of 22.carbon fatty acid in ether phospholipids

1982 • 41 citations

The biosynthesis of plasmalogens by rat brain: Involvement of the microsomal electron transport system

1975 • 38 citations

Increased fluorescence polarization of 1,6‐diphenyl‐1,3,5‐hexatriene in the phorbol myristate acetate‐stimulated plasma membrane of human neutrophils

1982 • 29 citations

Ether-phospholipid composition in neutrophile and platelets

1985 • 25 citations