Neuronal Migration, Cerebral Cortical Development, and Cerebral Cortical Anomalies

CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES

1997 • 2,470 citations

Mode of cell migration to the superficial layers of fetal monkey neocortex

1972 • 2,145 citations

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

1995 • 1,720 citations

Interneuron Migration from Basal Forebrain to Neocortex: Dependence on Dlx Genes

1997 • 1,421 citations

Doublecortin Is a Microtubule-Associated Protein and Is Expressed Widely by Migrating Neurons

1999 • 1,297 citations

Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2

1999 • 1,231 citations

Regulation, substrates and functions of src

1996 • 1,173 citations

Isolation of a Miller–Dicker lissencephaly gene containing G protein β-subunit-like repeats

1993 • 1,067 citations

doublecortin, a Brain-Specific Gene Mutated in Human X-Linked Lissencephaly and Double Cortex Syndrome, Encodes a Putative Signaling Protein

1998 • 1,019 citations

Direct Binding of Reelin to VLDL Receptor and ApoE Receptor 2 Induces Tyrosine Phosphorylation of Disabled-1 and Modulates Tau Phosphorylation

1999 • 902 citations

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

1996 • 901 citations

The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons

1995 • 882 citations

Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations

2000 • 867 citations

Mutations in filamin 1 Prevent Migration of Cerebral Cortical Neurons in Human Periventricular Heterotopia

1998 • 858 citations

CENTRAL NERVOUS SYSTEM NEURONAL MIGRATION

1999 • 808 citations

Reelin Is a Ligand for Lipoprotein Receptors

1999 • 803 citations

An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy

1998 • 797 citations

A Novel CNS Gene Required for Neuronal Migration and Involved in X-Linked Subcortical Laminar Heterotopia and Lissencephaly Syndrome

1998 • 740 citations

Src family kinases are required for integrin but not PDGFR signal transduction

1999 • 733 citations

Mice Lacking p35, a Neuronal Specific Activator of Cdk5, Display Cortical Lamination Defects, Seizures, and Adult Lethality

1997 • 727 citations

Embryonic vertebrate central nervous system: Revised terminology

1970 • 716 citations

Principles of neural cell migration

1990 • 659 citations

Scrambler and yotari disrupt the disabled gene and produce a reeler -like phenotype in mice

1997 • 637 citations

Neocortical histogenesis in normal and reeler mice: A developmental study based upon [3H]thymidine autoradiography

1982 • 629 citations

Developmental Neuropathology

1989 • 591 citations

Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality

1998 • 571 citations

Reelin Binds α3β1 Integrin and Inhibits Neuronal Migration

2000 • 564 citations

Expression of Constitutively Active α-PAK Reveals Effects of the Kinase on Actin and Focal Complexes

1997 • 560 citations

Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring.

1990 • 522 citations

Reelin Is a Secreted Glycoprotein Recognized by the CR-50 Monoclonal Antibody

1997 • 512 citations

A LIS1/NUDEL/Cytoplasmic Dynein Heavy Chain Complex in the Developing and Adult Nervous System

2000 • 506 citations

NUDEL Is a Novel Cdk5 Substrate that Associates with LIS1 and Cytoplasmic Dynein

2000 • 482 citations

Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor

1994 • 473 citations

Congenital progressive muscular dystrophy of the fukuyama type — clinical, genetic and pathological considerations —

1981 • 469 citations

The small GTPase RalA targets filamin to induce filopodia

1999 • 449 citations

Architectonic map of neocortex of the normal mouse

1975 • 447 citations

Diagnostic criteria for Walker‐Warburg syndrome

1989 • 446 citations

A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function

2000 • 432 citations

Molecular biology of the cell (2nd edn)

1989 • 424 citations

Mechanisms of actin rearrangements mediating platelet activation.

1992 • 413 citations

N-CAM mutation inhibits tangential neuronal migration and is phenocopied by enzymatic removal of polysialic acid

1994 • 412 citations

Dynamics of Cell Migration from the Lateral Ganglionic Eminence in the Rat

1996 • 405 citations

The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

1998 • 403 citations

Origin and Route of Tangentially Migrating Neurons in the Developing Neocortical Intermediate Zone

1997 • 391 citations

A Classification Scheme for Malformations of Cortical Development

1996 • 389 citations

Neuregulin and erbB Receptors Play a Critical Role in Neuronal Migration

1997 • 381 citations

Cables Links Cdk5 and c-Abl and Facilitates Cdk5 Tyrosine Phosphorylation, Kinase Upregulation, and Neurite Outgrowth

2000 • 378 citations

Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex

1997 • 366 citations

LIS1 and XLIS (DCX) mutations cause most classical lissencephaly, but different patterns of malformation

1998 • 352 citations

Cell Migration from the Ganglionic Eminences Is Required for the Development of Hippocampal GABAergic Interneurons

2000 • 349 citations

NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration.

1995 • 337 citations

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development

1997 • 337 citations

Lissencephaly and Other Malformations of Cortical Development: 1995 Update

1995 • 323 citations

An Olfactory Sensory Map Develops in the Absence of Normal Projection Neurons or GABAergic Interneurons

1998 • 322 citations

Cyclin-Dependent Kinase 5-Deficient Mice Demonstrate Novel Developmental Arrest in Cerebral Cortex

1998 • 315 citations

Periventricular Heterotopia: An X-Linked Dominant Epilepsy Locus Causing Aberrant Cerebral Cortical Development

1996 • 301 citations

LIS1 Regulates CNS Lamination by Interacting with mNudE, a Central Component of the Centrosome

2000 • 296 citations

Periventricular and subcortical nodular heterotopia A study of 33 patients

1995 • 289 citations

Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.

1996 • 286 citations

Proteins of the CNR Family Are Multiple Receptors for Reelin

1999 • 276 citations

Mutations in the X-linked filamin 1 gene cause periventricular nodular heterotopia in males as well as in females

2001 • 274 citations

Doublecortin Is the Major Gene Causing X-Linked Subcortical Laminar Heterotopia (SCLH)

1998 • 262 citations

CNS Gene Encoding Astrotactin, Which Supports Neuronal Migration Along Glial Fibers

1996 • 256 citations

Cellular and Molecular Guidance of GABAergic Neuronal Migration from an Extracortical Origin to the Neocortex

1999 • 243 citations

Separate Progenitors for Radial and Tangential Cell Dispersion during Development of the Cerebral Neocortex

1998 • 237 citations

Muscle-eye-brain disease (MEB)

1989 • 234 citations

Clinical and molecular diagnosis of Miller-Dieker syndrome.

1991 • 232 citations

Differences in the gyral pattern distinguish chromosome 17–linked and X-linked lissencephaly

1999 • 224 citations

DLX-2, MASH-1, and MAP-2 expression and bromodeoxyuridine incorporation define molecularly distinct cell populations in the embryonic mouse forebrain

1994 • 215 citations

Astrotactin provides a receptor system for CNS neuronal migration

1991 • 215 citations

Tenascin promotes cerebellar granule cell migration and neurite outgrowth by different domains in the fibronectin type III repeats.

1992 • 211 citations

Mechanisms of glial-guided neuronal migration in vitro and in vivo

1990 • 199 citations

The architecture of actin filaments and the ultrastructural location of actin-binding protein in the periphery of lung macrophages.

1986 • 196 citations

A Revision of the Lissencephaly and Miller-Dieker Syndrome Critical Regions in Chromosome 17p13.3

1997 • 194 citations

Clinical and genetic distinction between Walker–Warburg syndrome and muscle–eye–brain disease

2001 • 184 citations

LIS1 and dynein motor function in neuronal migration and development

2001 • 169 citations

Characterization of mutations in the genedoublecortin in patients with double cortex syndrome

1999 • 166 citations

Mutation analysis of the DCX gene and genotype/phenotype correlation in subcortical band heterotopia

2001 • 160 citations

Actin-binding protein promotes the bipolar and perpendicular branching of actin filaments.

1980 • 156 citations

Periventricular heterotopia and epilepsy

1994 • 155 citations

Syndromes with lissencephaly. II: Walker‐Warburg and Cerebro‐Oculo‐Muscular syndromes and a new syndrome with type II lissencephaly

1985 • 154 citations

Magnetic resonance imaging in classification of congenital muscular dystrophies with brain abnormalities

1997 • 152 citations

Retrovirally introduced antisense integrin RNA inhibits neuroblast migration in vivo

1992 • 151 citations

Subcortical Band Heterotopia in Rare Affected Males Can be Caused by Missense Mutations in DCX (XLIS) or LIS1

1999 • 145 citations

The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC

1998 • 138 citations

Assignment of the Muscle-Eye-Brain Disease Gene to 1p32-p34 by Linkage Analysis and Homozygosity Mapping

1999 • 137 citations

Somatic and Germline Mosaic Mutations in the doublecortin Gene Are Associated with Variable Phenotypes

2000 • 129 citations

Neuroimaging manifestations and classification of congenital muscular dystrophies.

1998 • 125 citations

Congenital malformations of the brain: Pathological, embryological, clinical, radiological, and genetic aspects

1995 • 115 citations

The location and type of mutation predict malformation severity in isolated lissencephaly caused by abnormalities within the LIS1 gene

2000 • 106 citations

Platelet-Activating Factor Receptor Stimulation Disrupts Neuronal MigrationIn Vitro

1998 • 105 citations

Subcortical laminar heterotopia and lissencephaly in two families: a single X linked dominant gene.

1994 • 104 citations

Antibodies that recognize astrotactin block granule neuron binding to astroglia

1990 • 87 citations

Structure, expression, and function of, Ng‐CAM a member of the immunoglobulin superfamily involved in neuron‐neuron and neuron‐glia adhesion

1992 • 84 citations

Syndromes with lissencephaly.

1996 • 79 citations

Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE

2000 • 79 citations

Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeleton

1999 • 71 citations

Periventricular nodular heterotopia in patients with filamin-1 gene mutations: neuroimaging findings

2000 • 70 citations

Fluorescence in situ hybridization analysis with LIS1 specific probes reveals a high deletion mutation rate in isolated lissencephaly sequence

1998 • 57 citations

Familial periventricular nodular heterotopia

1993 • 50 citations

A Sibship with a Neuronal Migration Defect, Cerebellar Hypoplasia and Congenital Lymphedema

1993 • 47 citations

Cell migration in the developing chick diencephalon

1997 • 45 citations

A new view of early cortical development

1998 • 45 citations

Cell adhesion molecule L1 guides cell migration in primary reaggregation cultures of mouse cerebellar cells

1992 • 44 citations

Clinical spectrum and genetic studies of Fukuyama congenital muscular dystrophy

1994 • 41 citations

Periventricular Heterotopia May Result From Radial Glial Fiber Disruption

2001 • 38 citations

Omphalocele in Miller-Dieker syndrome: Expanding the phenotype

1997 • 35 citations

The role of cytoplasmic dynein in the human brain developmental disease lissencephaly

2000 • 35 citations

Commissural fibers may guide cholinergic neuronal migration in developing rat cervical spinal cord

1995 • 34 citations

Development of the cortical dysplasia of type II lissencephaly

1993 • 33 citations

Incidence and distribution of neomembranes of dura mater

1971 • 33 citations

Familial lissencephaly with cleft palate and severe cerebellar hypoplasia

1999 • 28 citations

Lissencephaly and subcortical band heterotopia: molecular basis and diagnosis

2000 • 27 citations

Familial lissencephaly with cleft palate and severe cerebellar hypoplasia

1999 • 24 citations

Fetal type II lissencephaly: a case report

1993 • 18 citations

The behavior of the reeler neurological mutant mouse.

1968 • 15 citations

Another Arab patient with overlap of Váradi-Papp/Opitz trigonocephaly syndromes?

1997 • 7 citations