Nucleotide sequence of the streptothricin acetyltransferase gene from Streptomyces lavendulae and its expression in heterologous hosts

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Experiments in molecular genetics

1972 • 28,260 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

1992 • 4,683 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

The relationship between base composition and codon usage in bacterial genes and its use for the simple and reliable identification of protein-coding sequences

1984 • 820 citations

Translational Initiation in Prokaryotes

1981 • 785 citations

Transformation of Salmonella typhimurium by Plasmid Deoxyribonucleic Acid

1974 • 777 citations

Cloning and Expression of the Tyrosinase Gene from Streptomyces antibioticus in Streptomyces lividans

1983 • 640 citations

Unique features in the ribosome binding site sequence of the gram-positive Staphylococcus aureus beta-lactamase gene.

1981 • 485 citations

Fate of transforming DNA following uptake by competent Bacillus subtilis

1971 • 452 citations

Homology among DNA-binding proteins suggests use of a conserved super-secondary structure

1982 • 432 citations

Plasmids, Recombination and Chromosome Mapping in Streptomyces lividans 66

1983 • 416 citations

Construction and characterisation of a series of multi-copy promoter-probe plasmid vectors for Streptomyces using the aminoglycoside phosphotransferase gene from Tn5 as indicator

1986 • 403 citations

Molecular cloning of the whole biosynthetic pathway of a Streptomyces antibiotic and its expression in a heterologous host

1984 • 358 citations

Cloning and analysis of the promoter region of the erythromycin-resistance gene (ermE) of Streptomyces erythraeus

1986 • 347 citations

Gene Cloning in Streptomyces

1982 • 335 citations

Gene expression in Streptomyces: Construction and application of promoter-probe plasmid vectors in Streptomyces lividans

1982 • 316 citations

Physical analysis of antibiotic-resistance genes from Streptomyces and their use in vector construction

1982 • 229 citations

Resistance, regulatory and production genes for the antibiotic methylenomycin are clustered.

1985 • 192 citations

Nucleotide sequences encoding and promoting expression of three antibiotic resistance genes indigenous to Streptomyces

1985 • 180 citations

The nucleotide sequence of the tyrosinase gene from Streptomyces antibioticus and characterization of the gene product

1985 • 171 citations

RNA polymerase heterogeneity in Streptomyces coelicolor

1985 • 167 citations

Nucleotide sequence of a streptomycete aminoglycoside phosphotransferase gene and its relationship to phosphotransferases encoded by resistance plasmids.

1983 • 157 citations

Nucleotide sequence of tbe hygromycin B phosphotransferase gene fromStreptomyces hygroscopicus

1986 • 124 citations

N-methyl transferase of Streptomyces erythraeus that confers resistance to the macrolidelincosamide-streptogramin B antibiotics: amino acid sequence and its homology to cognate R-factor enzymes from pathogenic bacilli and cocci

1985 • 110 citations

Self-cloning in Streptomyces griseus of an str gene cluster for streptomycin biosynthesis and streptomycin resistance

1985 • 109 citations

Genetic and Biochemical Characterization of the red Gene Cluster of Streptomyces coelicolor A3(2)

1985 • 89 citations

Construction and application of a promoter-probe plasmid that allows chromogenic identification in Streptomyces lividans

1985 • 66 citations

Promoter recognition by sigma-37 RNA polymerase from Bacillus subtilis

1984 • 61 citations

Nucleotide sequence of afsB, a pleiotropic gene involved in secondary metabolism in Streptomyces coelicolor A3(2) and "Streptomyces lividans"

1986 • 48 citations

Developments in Streptomyces Cloning

1983 • 40 citations

Cro Repressor Protein and Its Interaction with DNA

1983 • 37 citations

Molecular cloning of a cellulase gene from Bacillus subtilis and its expression in Escherichia coli.

1986 • 27 citations

Cloning and characterization of the streptothricin-resistance gene which encodes streptothricin acetyltransferase from Streptomyces lavendulae.

1986 • 19 citations

Molecular cloning of Thermus flavus malate dehydrogenase gene.

1986 • 12 citations

Molecular Cloning ofThermus flavusMalate Dehydrogenase Gene

1986 • 9 citations