Homology among DNA-binding proteins suggests use of a conserved super-secondary structure

A general method applicable to the search for similarities in the amino acid sequence of two proteins

1970 • 11,049 citations

Principles of protein structure

1980 • 1,094 citations

Principles of Protein Structure

1979 • 1,090 citations

Similar Amino Acid Sequences: Chance or Common Ancestry?

1981 • 855 citations

Cleavage of the Escherichia coli lexA protein by the recA protease.

1980 • 550 citations

Structure of the cro repressor from bacteriophage λ and its interaction with DNA

1981 • 545 citations

DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli.

1980 • 534 citations

The operator-binding domain of λ repressor: structure and DNA recognition

1982 • 528 citations

How the λ repressor and cro work

1980 • 452 citations

A THEORY OF MODULAR EVOLUTION FOR BACTERIOPHAGES*

1980 • 437 citations

Mechanism of action of the lexA gene product.

1981 • 424 citations

λ Repressor and cro—components of an efficient molecular switch

1981 • 385 citations

Nucleic Acid-Protein Recognition

1977 • 343 citations

Escherichia coli recA gene product inactivates phage lambda repressor.

1978 • 305 citations

Purified λ regulatory protein cII positively activates promoters for lysogenic development

1981 • 241 citations

The lambda repressor contains two domains.

1979 • 238 citations

A mutant of Escherichia coli showing constitutive expression of the lysogenic induction and error-prone DNA repair pathways.

1977 • 231 citations

How lac Repressor Binds to DNA

1972 • 228 citations

Nucleotide sequence of cro, cII and part of the O gene in phage λ DNA

1978 • 222 citations

Regulation of SOS functions: Purification of E. coli LexA protein and determination of its specific site cleaved by the RecA protein

1981 • 178 citations

Structural similarity in the DNA-binding domains of catabolite gene activator and cro repressor proteins.

1982 • 171 citations

An amino-terminal fragment of lac repressor binds specifically to lac operator

1978 • 164 citations

Properties of hybrids between Salmonella phage P22 and coliphage λ

1974 • 149 citations

Mechanism of action of the cro protein of bacteriophage lambda.

1978 • 145 citations

Regulatory functions of the λ repressor reside in the amino-terminal domain

1979 • 143 citations

Structure of the DNA-binding region of lac repressor inferred from its homology with cro repressor.

1982 • 142 citations

Isolation of the amino-terminal fragment of lactose repressor necessary for DNA binding

1977 • 139 citations

Cleavage of the lambda and P22 repressors by recA protein.

1982 • 139 citations

Nucleotide sequence of the lexA gene of E. coli

1981 • 124 citations

DNA sequence of the bacteriophage λ cI gene

1978 • 121 citations

The N-terminal arms of λ repressor wrap around the operator DNA

1982 • 118 citations

Primary structure of the λ repressor

1978 • 118 citations

Sequence of galR gene indicates a common evolutionary origin of lac and gal repressor in Escherichia coli.

1982 • 108 citations

Amino acid sequence of Cro regulatory protein of bacteriophage lambda

1977 • 104 citations

Kinetics of recA protein-directed inactivation of repressors of phage λ and phage P22

1980 • 94 citations

Mutant lambda phage repressor with a specific defect in its positive control function.

1982 • 93 citations

Sequence of cro gene of bacteriophage lambda

1977 • 84 citations

Primary structure of the phage P22 repressor and its gene c2

1981 • 70 citations

Amino‐Acid Sequence of lac Repressor from Escherichia coli

1975 • 67 citations

Nucleotide sequence of the cro - cII - oop region of bacteriophage 434 DNA

1979 • 59 citations

Lac Repressor: a proton magnetic resonance look at the deoxyribonucleic acid binding fragment

1981 • 49 citations

Iodination of Escherichia coli lac repressor. Effect of tyrosine modification on repressor activity

1975 • 42 citations

Altered Sequences Changing the Operator-Binding Properties of the Lac Repressor: Colinearity of the Repressor Protein with the i -Gene Map

1972 • 36 citations

Primary structure of an EcoRI fragment of λimm434 DNA containing regions cI-cro of phage 434 and cII-O of phage lambda

1979 • 30 citations

Modification of tyrosine residues of the lactose repressor protein

1977 • 27 citations

Similarities between Lac Repressor and Lambda Repressor

1977 • 11 citations