Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization

1996 • 873 citations

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases.

1996 • 667 citations

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

1998 • 656 citations

A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases

1995 • 625 citations

Rho Family GTPases and Neuronal Growth Cone Remodelling: Relationship between Increased Complexity Induced by Cdc42Hs, Rac1, and Acetylcholine and Collapse Induced by RhoA and Lysophosphatidic Acid

1997 • 601 citations

Rac and Cdc42 Induce Actin Polymerization and G1 Cell Cycle Progression Independently of p65PAK and the JNK/SAPK MAP Kinase Cascade

1996 • 571 citations

Actin-Dependent Propulsion of Endosomes and Lysosomes by Recruitment of N-Wasp✪

2000 • 444 citations

Spatial control of coated-pit dynamics in living cells

1999 • 435 citations

Molecular Links between Endocytosis and the Actin Cytoskeleton

2000 • 417 citations

Mechanisms of actin rearrangements mediating platelet activation.

1992 • 413 citations

EPS8 and E3B1 transduce signals from Ras to Rac

1999 • 329 citations

Endocytic vesicles move at the tips of actin tails in cultured mast cells

1999 • 325 citations

Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling.

1992 • 321 citations

Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product.

1994 • 314 citations

Intersectin, a Novel Adaptor Protein with Two Eps15 Homology and Five Src Homology 3 Domains

1998 • 291 citations

SH3-domain-containing proteins function at distinct steps in clathrin-coated vesicle formation

1999 • 275 citations

Signaling to Actin Dynamics

1999 • 260 citations

The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15

1999 • 236 citations

Dap160, a Neural-specific Eps15 Homology and Multiple SH3 Domain-containing Protein That Interacts with DrosophilaDynamin

1998 • 205 citations

A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways.

1994 • 195 citations

Splice Variants of Intersectin Are Components of the Endocytic Machinery in Neurons and Nonneuronal Cells

1999 • 180 citations

The endocytic machinery in nerve terminals surrounds sites of exocytosis

1999 • 172 citations

Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex

2001 • 172 citations

Characterization of p190RhoGEF, A RhoA-specific Guanine Nucleotide Exchange Factor That Interacts with Microtubules

2001 • 172 citations

Identification of the Major Synaptojanin-binding Proteins in Brain

1997 • 169 citations

EHSH1/Intersectin, a Protein That Contains EH and SH3 Domains and Binds to Dynamin and SNAP-25

1999 • 163 citations

Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift

2001 • 162 citations

Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I.

1994 • 160 citations

Synaptojanin Forms Two Separate Complexes in the Nerve Terminal

1997 • 138 citations

Phosphatidylinositol 3-Kinase, Cdc42, and Rac1 Act Downstream of Ras in Integrin-Dependent Neurite Outgrowth in N1E-115 Neuroblastoma Cells

2000 • 125 citations

Two Pathways through Cdc42 Couple the N-Formyl Receptor to Actin Nucleation in Permeabilized Human Neutrophils

2000 • 116 citations

Two Isoforms of a Human Intersectin (ITSN) Protein Are Produced by Brain-Specific Alternative Splicing in a Stop Codon

1998 • 102 citations

The endocytic protein intersectin is a major binding partner for the Ras exchange factor mSos1 in rat brain

2000 • 94 citations

Intersectin 2, a new multimodular protein involved in clathrin‐mediated endocytosis

2000 • 91 citations

G protein βγ subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25 ^Mm

1999 • 83 citations

CdGAP, a Novel Proline-rich GTPase-activating Protein for Cdc42 and Rac

1998 • 81 citations